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61.
研究有氧运动对青少年骨骼肌細胞葡萄糖代谢的影响,因为青少年骨骼肌細胞葡萄糖氧化代谢规律和青年小鼠是相同的。为了便于采集骨骼肌细胞將青年小鼠作为研究対象,选用3月龄健康雄性Sprague-Dawley小鼠30只,随机将其划分成安静组、中等强度有氧运动组和过度有氧运动组,每组10只洧氧运动方式为游泳。经7周有氧运动后,中等强度有氧运动组体重、体重变化和体重变化率均显著低于对照组(P0.05);过度有氧运动组各体重指标均低于对照组,差异具有非常显著性(P0.01)。经7周有氧运动后,中等强度有氧运动组血糖显著低于对照组(P0.05),血清胰岛素显著高于对照组(P0.05)过度有氧运动组血糖低于对照组血清胰岛素高于对照组差异均具有非常显著性(P0.01)。经7周有氧运动后,中等强度有氧运动组和过度有氧运动组GT4含量均显著高于对照组(P0.05)。经7周有氧运动后,中等强度有氧运动组和过度有氧运动组MEF2mRNA表达均高于对照组差异具有非常显著性(P0.01)。说明适宜有氧运动能够促进青少年骨骼肌細胞葡萄糖代谢,但过度有氧运动会使机体在一定程度上受到损伤。 相似文献
62.
63.
文章通过对舞蹈解剖学的系统阐述,说明人体各个器官、系统的形态、结构特征的相互关系。以及舞蹈训练对人体形态结构产生的影响,初步分析了运用解剖学的基础知识分析舞蹈动作的方法,以及运用舞蹈解剖学知识,预防身体损伤的方法。 相似文献
64.
G. Bailin 《Cellular and molecular life sciences : CMLS》1984,40(11):1185-1188
Summary In smooth muscle the Mr 20,000 light chain of myosin is phosphorylated by a calmodulin-dependent protein kinase. It consists of 2 subunits: calmodulin, an acidic protein of Mr 17,000 that binds 4 moles of Ca2+; and a larger protein of Mr circa 130,000. Activation of the kinase is dependent upon their association in the presence of Ca2+. Cyclic AMP-dependent protein kinase phosphorylation of the myosin light chain kinase occurs at 2 sites. It decreases the affinity of the kinase for calmodulin and a reduction in the rate of light chain phosphorylation occurs. The kinase has an overall asymmetric shape composed of a globular head and tail region for the skeletal muscle enzyme. Trypsin digestion of this kinase releases a fragment of Mr 36,000 from the globular region that contains the catalytic and calmodulin binding sites. Chymotrypsin digestion of the kinase from smooth muscle generates a fragment of Mr 80,000 that does not contain the calmodulin binding or cyclic AMP-dependent protein kinase phosphorylation sites. It is a Ca2+-independent form of the kinase that phosphorylates the light chain of myosin. These structural features indicate a regulatory role for the kinase in smooth muscle phosphorylation and contraction. 相似文献
65.
K. R. Weiss V. Březina E. C. Cropper S. L. Hooper M. W. Miller W. C. Probst F. S. Vilim I. Kupfermann 《Cellular and molecular life sciences : CMLS》1992,48(5):456-463
Despite their ubiquitous presence in the central and peripheral nervous systems, the behavioral functions of peptide co-transmitters remain to be elucidated. The marine molluscAplysia, whose simple nervous system facilitates the study of the neural basis of behavior, was used to investigate the role of peptidergic co-transmission in feeding behavior. Several novel modulatory neuropeptides were purified, and localized to identified cholinergic motorneurons. Physiological and biochemical studies demonstrated that these peptides are released when the motorneourons fire at frequencies that occur during normal behavior, and that the peptides modify the relationship between muscle contraction amplitude and relaxation rate so as to maintain optimal motor output when the intensity and frequency of feeding behavior change. 相似文献
66.
N. Ishii 《Cellular and molecular life sciences : CMLS》1986,42(7):810-812
Summary The maximal unloaded shortening velocity (Vmax) of smooth muscle cells isolated from the pedal retractor muscle ofMytilus was more than twice as large as that of the whole muscle, suggesting the presence of extracellular components which resist the contraction of the whole muscle. The Vmax of the isolated cells was almost constant at cell lengths ranging between 0.5 and 0.8310 (10, optimal length for tension generation) indicating that the intracellular resistance to contraction is negligible within this range of lengths. 相似文献
67.
O. V. Subramanyam 《Cellular and molecular life sciences : CMLS》1984,40(12):1423-1424
Summary Blood sugars and foot muscle glycogen were measured in the mussel,L. marginalis after ablation of the cerebral ganglia, and in mussels injected with cerebral ganglionic extract 3 h after ablation. There is a rise in the blood sugar and decrease in foot muscle glycogen 3 h after operation, but no change in sham-operated controls. The effect of ablation is reversed by injecting brain extract into ablated mussels. No such effect could be seen in the controls. The results are suggestive of the presence, in the cerebral ganglia, of a hypoglycaemic factor similar to insulin. 相似文献
68.
T. A. Robertson J. M. Papadimitriou M. D. Grounds 《Cellular and molecular life sciences : CMLS》1992,48(4):394-395
In this report we demonstrate for the first time that differentiating myogenic cells, geographically located between the plasmalemma and external lamina of myofibres in the satellite cell position3, can fuse directly with the plasmalemma of undamaged segments of mature myofibres. 相似文献
69.
葡萄糖转运体4(GLUT4)是转运葡萄糖的重要蛋白质,与Ⅱ型糖尿病(T2DM)密切相关.从GLUT4对骨骼肌、心肌和脂肪组织,以及肾组织的肾小球系膜细胞的影响等方面进行了综述,研究葡萄糖转运体4与Ⅱ型糖尿病相互关系. 相似文献
70.
气动人工肌肉驱动仿人灵巧手的结构设计 总被引:2,自引:1,他引:1
研究一种气动人工肌肉驱动的多指仿人灵巧手的结构设计. 通过分析正常人体解剖学,针对人类手掌的外形结构、驱动形式及运动规则,设计了一种5指仿人灵巧手. 该灵巧手有5个手指、19个自由度,在外观和功能上与人手接近;手指采用气动人工肌肉驱动,以柔索传动. 实验结果表明,该仿人灵巧手具有很好的柔顺性,并且整体外形和手指关节的运动范围均能达到拟人的效果. 相似文献