一类资源分配问题的最优化方法的研究

建立了树型生产系统的一类资源分配问题的数学模型和计算法,并给出一般网络简化为树型网络的树化变换。然后建立了一般生产系统资源分配问题的网络优化算法。     

城市土地规划的优化方法研究

以多目标决策理论、组合优化理论以及预测科学技术为依据 ,首先建立了土地功能配置模型 ,帮助规划师对各种不同功能土地的片面布置进行分析 ,从而找到最合理的城市土地布局 ;然后以遗传算法作为优化工具 ,对建立的模型进行了优化。     

一类按学生素质优劣排序的数学方法

用模糊学方法定量评定了学生的综合素质，并按素质的优劣给学生进行了排序，这里是将数学方法引入教学管理的初步尝试。     

反应精馏过程的操作优化与集成优化分析

为优化反应精馏工业装置操作,分析了反应精馏过程优化问题的内容和特点,提出了一套行之有效的优化策略,并建立了典型过程的以经济效益为目标、符合过程约束和质量及转化率约束的优化数学模型。对MTBE装置进行了操作优化分析,可提高年经济效益1.62%。提出了反应精馏过程的集成优化思想,通过对乳酸提纯反应精馏装置进行集成优化分析,可有效确定过程的最优设计参数,并提高年经济效益8.23%。计算结果表明:该模型及其算法可有效用于反应精馏过程的优化分析。通过优化计算可取得明显的经济效益。     

Specific anti-tumor effect induced by attenuated Salmonella typhimurium vaccine expressing extracellular region of vascular endothelial growth factor receptor 2

The purposes of this research were to study the stable expression of exogenous gene encoding therapeutic protein in attenuated Salmonella typhimurium, observe the metabolism of oral gene vaccine carried by attenuated Salmonella typhimurium in BALB/c mouse, and investigate the feasibility of prevention and treatment of tumors by the recombinant bacteria. Recombinant plasmid pcDNA3.1 VEGFR2(n1-7) was transformed into competent attenuated Salmonella typhimurium SL3261 to develop oral DNA vaccine SL3261-pcDNA3.1 VEGFR2(n1-7). To observe whether the exogenous gene can be expressed in the recombinant bacteria, PCR was performed to amplify the CMV promoter of the eukaryotic expression vector as the proof of stable expression of exogenous protein; transmission elec- tron microscopy (TEM) was applied to observe the morphology of the recombinant bacteria to confirm that the exogenous gene has no impact on the growth of the bacteria, and then BALB/c mice were immunized with the gene vaccine. After inoculation of the gene vaccine, the recombinant bacteria SL3261 could be detected in the tissues such as small intestine, colon, liver and spleen. And then, mice in each group were challenged with tumor cells. The results of animal experiment showed that tumor growth of the mice in experimental group was inhibited and survival time of immunized mice was prolonged compared with control groups. A higher lymphocyte infiltration in tumors from animals treated with DNA vaccine was observed. Immunohistochemical analysis of tumor samples revealed an en- hanced accumulation of CD8 cytotoxic T lymphocytes, as well as an increase in CD4 cells in the tumors of animals treated with the oral gene vaccine compared to tumors from control group mice. Ultrastructure of the tumor tissue showed that tumor cells in the samples of the immunized mice were well-differentiated. Our research confirmed that the exogenous gene can be stably expressed in the attenuated Salmonella typhimurium and has no impact on the growth of the recombinant bacteria; the exogenous gene can de delivered to the host by attenuated Salmonella typhimurium to produce anti-tumor effect with no obvious cytotoxity to the host. In this study, it is established that attenuated Salmonella typhimurium could be used as a vector for oral gene vaccine, and our study provided a theoretical basis for the body distribution and the metabolism of the recombinant bacteria. This strategy may provide a simple, safe and effective way for the prevention and treatment of tumors.     

处理优化约束条件的微分方程法

在文[1]中,作者曾提出求解一般约束优化问题的一种新方法。本文利用微分方程对约束条件做进一步的讨论,证明了从一可行点的某邻域出发的该微分方程组的解关于部分变元总收敛到问题(1.1)的可行点。     

电子线路的数值优化设计

研究了电子线路的数值化设计方法.它是一种自动化程度高、通用性强、精度高的电路设计方法。介绍了电子线路数值优化设计软件系统YJX—1.它具有广泛的通用性和快速收敛的特点。     

发电厂相变干冷排热系统优化与不确定性分析初探

通过火力发电厂相变空气干式冷却排热系统的热经济学分析，提出了相变干式冷却系统优化的目标函数和优化参数，利用数值计算的可变容差法进行优化计算，取得了满意的结果，为了保证优化在可变经济环境的可靠性动力稳定性， 对优化结果进行了不确定性分析。     

椭圆偏振光理论中一个问题的证明

本文从椭偏光合矢量旋转角速度Ω的表达式出发，对只有沿椭圆长、短轴方向的椭偏光合矢量间的相位差才为的难点给出了证明     

改进QDPSO算法在BP网络训练中的应用

QDPSO（Quantum Delta-Potential-Well-based Particle Swarm Optimization）算法是基于量子空间的粒子群算法，对QDPSO算法进行了改进，结合Iris分类问题，应用到BP网络的权值优化中，并和基于标准PSO算法的方法进行了比较。实验结果表明：该算法性能优于所比较的两种算法，并且具有良好的收敛性和稳定性。