一种新的模糊神经网络删剪策略

模糊规则的数量直接决定模糊神经网络结构的复杂度和效率.基于神经网络自构行学习(NNSCL)算法,用共轭剃度预条件正则方程算法求取删除隐层神经元后的剩余权值,得到改进的NNSCL-1算法.将此算法应用到模糊神经网络的规则推理层,可以极大地优化网络的规则及结构,并且结构优化后不需要重新训练也能保持网络的精确度和泛化能力.仿真结果显示了此算法的有效性和可行性.     

Lidstone边值问题多个单调正解的存在性

对含有各阶导数的2m阶微分方程:y(2m)(t)=f(t,y(t),y′(t),…,y(2m-2)(t),y(2m-1)(t)),t∈(0,1),y(2i+1)(0)=y(2i)(1)=0,0≤i≤m-1,其中(-1)mf:[0,1]×R2m→[0,∞)是连续的。笔者首先给出方程的Green函数及其一些性质,并赋予f一定的增长条件,利用5个泛函的不动点定理,然后给出上述边值问题的3个单调正解的存在性。     

弦振泛频分析及演奏中的泛音

根据弦振驻波的规律,证明了弦乐器振动中各次振动的振幅递减之规律,给出了演奏中准确的泛音触弦位置,揭示了拉弦类乐器泛音的物理本质,是设计扩展音域、增加自然泛音的理论根据。     

存储过程在管理信息系统开发中的应用

存储过程是一种重要的数据库对象,恰当地使用存储过程可以简化应用程序的开发,增强管理信息系统的灵活性及安全性.     

用MATLAB求解Butterworth最优传递函数

采用MATLAB语言编写函数bwden,通过主程序调用该函数可求出任意阶Butterworth最优传递函数分母多项式的系数,绘制出Butterworth最优传递函数的极点分布图,阶跃响应曲线及波德图.8阶Butter-worth最优传递函数的求解和仿真表明,可有效且简便地用MATLAB求解Butterworth最优传递函数.     

DNA methylation of fly genes and transposons

The use of anti-5-methylcytosine antibodies in affinity columns allowed the identification of methylated sequences in the genome of Drosophila melanogaster adults. In view of the presence of transposable elements amongst the identified sequences, it has been suggested that DNA methylation is involved in transposon control in the fly genome. On the contrary, a reanalysis of these data furnishes several intriguing elements that could raise new questions about the role that DNA methylation plays in the fly genome. The aim of the present paper is to discuss some features that emerge from the analysis of the identified methylated sequences. Received 26 January 2006; received after revision 8 May 2006; accepted 2 June 2006     

Betaine homocysteine S-methyltransferase: just a regulator of homocysteine metabolism?

Betaine homocysteine methyltransferase (BHMT), a Zn²⁺-dependent thiolmethyltransferase, contributes to the regulation of homocysteine levels, increases in which are considered a risk factor for cardiovascular diseases. Most plasma homocysteine is generated through the liver methionine cycle, in which BHMT metabolizes approximately 25% of this non-protein amino acid. This process allows recovery of one of the three methylation equivalents used in phosphatidylcholine synthesis through transmethylation, a major homocysteine-producing pathway. Although BHMT has been known for over 40 years, the difficulties encountered in its isolation precluded detailed studies until very recently. Thus, the last 10 years, since the sequence became available, have yielded extensive structural and functional data. Moreover, recent findings offer clues for potential new functions for BHMT. The purpose of this review is to provide an integrated view of the knowledge available on BHMT, and to analyze its putative roles in other processes through interactions uncover to date. Received 26 May 2006; received after revision 3 July 2006; accepted 24 August 2006     

Lipid-lowering drugs

Although a change in life-style is often the method of first choice for lipid lowering, lipid-lowering drugs, in general, help to control elevated levels of different forms of lipids in patients with hyperlipidemia. While one group of drugs, statins, lowers cholesterol, the other group, fibrates, is known to take care of fatty acids and triglycerides. In addition, other drugs, such as ezetimibe, colesevelam, torcetrapib, avasimibe, implitapide, and niacin are also being considered to manage hyperlipidemia. As lipids are very critical for cardiovascular diseases, these drugs reduce fatal and nonfatal cardiovascular abnormalities in the general population. However, a number of recent studies indicate that apart from their lipidlowering activities, statins and fibrates exhibit multiple functions to modulate intracellular signaling pathways, inhibit inflammation, suppress the production of reactive oxygen species, and modulate T cell activity. Therefore, nowadays, these drugs are being considered as possible therapeutics for several forms of human disorders including cancer, autoimmunity, inflammation, and neurodegeneration. Here I discuss these applications in the light of newly discovered modes of action of these drugs. Received 5 September 2005; received after revision 29 December 2005; accepted 26 January 2006     

一种逐步优化灰导数背景值的GM(1,1)建模方法

证明了离散齐次指数函数经一次累加生成后为离散非齐次指数.进而在GM(1,1)以均值生成作为灰导数背影值的基础上,进一步提出了一种逐步优化灰导数背景值的方法,提高了建模精度,特别对于绝对灰度为0(或很小)的具有齐次灰指数律的数据,应用该方法可以得到十分理想的预测模型.     

航天器控制过程中离散事件动态控制策略研究

对离散事件系统动态控制理论进行了阐述,对航天飞行器控制过程进行了分析研究,指出了航天器控制过程中包含了一系列的离散事件,具有离散事件动态控制的特性,是一种广义的离散事件系统控制.测控专家和测控人员共同完成对整个航天器测控过程的分析判断,提出相应的控制策略,实施对航天器系统的控制.在此基础上,根据广义情况下离散事件动态控制的特点,提出了一种适用于航天器控制过程的离散事件动态控制模型,指出了此模型在航天器控制过程中应用的优点,并进一步指出广义离散事件系统动态控制模型可以应用于其它相关领域.