Effect of matrix metallo-proteinase-26 (MMP-26) during embryo implantation in the mouse

Matrix metalloproteinase-26 (MMP-26, endometase and matrilysin-2), a novel member of the MMPs family, is detected not only in the placenta and uterus, but is widely expressed in malignant tumors from different sources as well as in diverse tumor cell lines. However, the function of MMP-26 in the reproductive system has never been reported. Expression of MMP-26 in mouse embryos and the function of the MMP-26 antibody during mouse embryo implantation was examined for the first time by injecting the uterine horn, immunohistochemistry,in situ hybridization, co-culture of mouse blastocysts and uterine monolayer epithelial cells, Western blot, RT-PCR, Northern blot and zymography. Our results show that there is strong expression of MMP-26 mRNA and protein in the mouse embryo. Furthermore, the MMP-26 antibody dramatically inhibited mouse embryo implantation and significantly inhibited adhesion and outgrowth of mouse blastocysts onin vitro uterine monolayer epithelial cells. At the same time, the MMP-26 antibody inhibited the expression of integrin αV mRNA and protein in a dose-dependent manner. These data suggest that MMP-26 may play a role in some of the tissue-remodeling events associated with the invasion of the endometrium by trophoblast cells and facilitate successfully embryo implantation.     

Landau theory of martensitic transformation in Fe-Mn-Si based alloys

Considering the features of martensitic transformation in Fe-Mn-Si based alloys, the Landau theory is established by introducing the density of stacking faults as a new order parameter ηand the corresponding free energy function. By using such an order parameter, the stacking fault mechanism of the nucleation and growth for the γ(fcc)→ε(hcp) martensitic transformation can be reasonably explained, and a further detailed mechanism is proposed. The stacking faults are generated and overlapped in an irregular form at the beginning and then becoming regular to create some transition structures till a stable phase forms at a certain temperature. The importance of the interface soliton is to complete the transformations into various structures of martensite but not the twinned one. The thermodynamics of fcc→hcp transformation and those between different transition structures are described by the free energy function established in the present note.     

Regularities of formation and lattice distortion of perovskite-type compounds

Based on 489 known perovskite-type complex oxides and a number of other type complex oxides, the pattern recognition-atomic parameter method is adopted to find regularities of the formation and the lattice distortion of the perovskite structure. It has been found that the restriction on Goldschmidt's t factor constitutes only a necessary but not a sufficient condition to form perovskite-type compounds. A more effective mathematical model, which can precisely sum up the regularities of the formation, the lattice distortion,and the cell constants of known perovskite-type compounds and reliably make corresponding predictions on unknown compounds, can be set up by integrating multiple atomic parameters such as ionic radii, ionic valency, and Basanov's electronegativity of constituent elements. Based on it, an intelligent database has been implemented. Its prediction accuracy is tested by eight newly discovered perovskite-type compounds such as Eu(Mn0.5 Ni0.5)O3, etc. (they are not included in the database during the test). The prediction resuits are in agreement with experimental facts.     

基于存储的矩阵乘积优化算法

提出了一种基于存储的矩阵乘积优化算法.该算法转置矩阵,提高cache命中率,从而降低矩阵乘积时间. 实验结果表明此算法是行之有效的.     

冠的拉普拉斯谱

主要研究冠的拉普拉斯谱.设G1 G2是两个简单连通图G1和G2的冠,L1是G1的拉普拉斯矩阵,μ1,μ2,…,μm是G2的拉普拉斯谱,且0=μ1<μ2≤…≤μm,利用分块矩阵证明了G1 G2的拉普拉斯矩阵L的特征多项式|λI-L|=[Πmi=2(λ-1-μi)n]-L1-(λ-m-1)IλI(λ-1)I,其中|V(G1)|=n,|V(G2)|=m.     

Application of adaptive filtering by selecting the parameter weight factor in precise kinematic GPS positioning

A new method of adaptive filtering by selecting the parameter weight factor is introduced in this paper. Based on the theoretical analysis and research, this method is firstly used for precise kinematic GPS positioning with single frequency double-differenced (DD) carrier phase observations. Two numerical examples are given to illustrate the feasibility and validity of the method. The preliminary results show that precise positioning results can be obtained by using only the GPS single frequency DD carrier phase measurements for short baselines with the new method.     

Research on the magnetic material of Sm-Fe matrix nitrides

In this paper, the types of Sm-Fe matrix compounds and their correlations are introduced, and progress of research on the magnetic materials of Sm-Fe matrix nitrides is also reviewed. Possible research trends of future permanent magnetic materials of SmFe matrix nitrides are briefly predicted.     

Rough set-based feature selection method

A new feature selection method is proposed based on the discern matrix in rough set in this paper. The main idea of this method is that the most effective feature, if used for classification, can distinguish the most number of samples belonging to different classes. Experiments are performed using this method to select relevant features for artificial datasets and real-world datasets. Results show that the selection method proposed can correctly select all the relevant features of artificial datasets and drastically reduce the number of features at the same time. In addition, when this method is used for the selection of classification features of real-world underwater targets,the number of classification features after selection drops to 20% of the original feature set, and the classification accuracy increases about 6% using dataset after feature selection.     

流变荷载试验曲线的模型识别及其应用

基于粘弹性理论,建立了流变荷载试验的Maxwell、广义Kelvin和Burgers3种流变模型的位移反演模式,并给出了根据现场试验流变曲线进行流变模型识别的简便方法。分析了岩体流变荷载试验曲线,给出了能反映试验区域内岩体变形规律的最佳流变模型,反演获得了试验区域内岩体的瞬时弹性模量、长期弹性模量、粘弹性模量和粘弹性系数。结果表明,描述试验点岩体在不同荷载级别情况下的最佳流变模型均为广义Kelvin模型,但其弹性模量有所差异,其量值范围为4194～5235MPa,平均弹性模量为4900.316MPa;平均长期弹性模量为3081.65MPa。计算表明所建立的反演公式是正确的,模型及参数识别过程简便、实用。     

火烧油层干式燃烧数值模拟及参数敏感性分析

利用数值模拟技术对室内燃烧管干式燃烧实验进行了拟合,研究了燃烧管内干式燃烧的动态变化特征,并且进行了参数敏感性分析。以辽河油田欢127块为例,初步设计了该块25-33井组的注气速度。结果表明,网格尺寸的选取应与燃烧带尺寸相当;增加燃烧反应的频率因子、降低活化能、增大注气速度,会加快燃烧反应,增加产液量;油藏初始温度对火烧油层驱油效果影响较大,而油藏初始压力则影响较小。初步设计25-33井组的注气速度为70 000 m3/d。