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71.
针对MSComm控件的不足,探讨在VB.Net2003中如何利用API函数来定义串行端口类,并通过一个应用实例介绍如何利用该类的声明来实现PC与可编程控制器之间的串行通信.这对开发高质量的串行通信有一定的应用和借鉴价值. 相似文献
72.
运用文献资料法和归纳演绎法,对我国普通高校实施体育俱乐部式教学模式的现状和发展进行分析.浅谈了俱乐部式存在的原因、概况,俱乐部的好处,研究存在的问题以及提出改进的建议,探索一种符合我国国情的体育俱乐部式教学模式的发展方向,使之从萌芽状态走向成熟,更趋完善. 相似文献
73.
The utility F-box for protein destruction 总被引:2,自引:1,他引:2
A signature feature of all living organisms is their utilization of proteins to construct molecular machineries that undertake the complex network of cellular activities. The abundance of a protein element is temporally and spatially regulated in two opposing aspects: de novo synthesis to manufacture the required amount of the protein, and destruction of the protein when it is in excess or no longer needed. One major route of protein destruction is coordinated by a set of conserved molecules, the F-box proteins, which promote ubiquitination in the ubiquitin-proteasome pathway. Here we discuss the functions of F-box proteins in several cellular scenarios including cell cycle progression, synapse formation, plant hormone responses, and the circadian clock. We particularly emphasize the mechanisms whereby F-box proteins recruit specific substrates and regulate their abundance in the context of SCF E3 ligases. For some exceptions, we also review how F-box proteins function through non-SCF mechanisms. 相似文献
74.
Src-family kinases (SFKs) regulate different granulocyte and monocyte/macrophage responses. Accumulating evidence suggests that members of this family are implicated in signal transduction pathways regulating phagocytic cell migration and recruitment into inflammatory sites. Macrophages with a genetic deficiency of SFKs display marked alterations in cytoskeleton dynamics, polarization and migration. This same phenotype is found in cells with either a lack of SFK substrates and/or interacting proteins such as Pyk2/FAK, c-Cbl and p190RhoGAP. Notably, SFKs and their downstream targets also regulate monocyte recruitment into inflammatory sites. Depending on the type of assay used, neutrophil migration in vitro may be either dependent on or independent of SFKs. Also neutrophil recruitment in in vivo models of inflammation may be regulated differently by SFKs depending on the tissue involved. In this review we will discuss possible mechanisms by which SFKs may regulate phagocytic cell migratory abilities. 相似文献
75.
76.
Conti B 《Cellular and molecular life sciences : CMLS》2008,65(11):1626-1630
A modest reduction in body temperature prolongs longevity and may retard aging in both poikilotherm and homeotherm animals. Some of the possible mechanisms mediating these effects are considered here with respect to major aging models and theories. 相似文献
77.
Leung JY Chapman JA Harris JA Hale D Chung RS West AK Chuah MI 《Cellular and molecular life sciences : CMLS》2008,65(17):2732-2739
Olfactory ensheathing cells (OECs) have been shown previously to express Toll-like receptors and to respond to bacteria by translocating nuclear factor-kappaB from the cytoplasm to the nucleus. In this study, we show that OECs extended significantly more pseudopodia when they were exposed to Escherichia coli than in the absence of bacteria (p=0.019). Co-immunoprecipitation showed that E. coli binding to OECs was mediated by Toll-like receptor 4. Lyso-Tracker, a fluorescent probe that accumulates selectively in lysosomes, and staining for type 1 lysosome-associated membrane proteins demonstrated that endocytosed FITC-conjugated E. coli were translocated to lysosomes. They appeared to be subsequently broken down, as shown by transmission electron microscopy. No obvious adherence to the membrane and less phagocytosis was observed when OECs were incubated with inert fluorescent microspheres. The ability of OECs to endocytose bacteria supports the notion that OECs play an innate immune function by protecting olfactory tissues from bacterial infection. 相似文献
78.
高校班主任在大学生思想政治教育和成长成才中发挥了十分积极的作用,但还存在着队伍不稳定、精力投入不足、结构不合理等问题。本文针对班主任的现状,从班主任自我完善、班团干部管理、学生副班主任使用、特殊学生帮扶、奖助学金配置、档案管理等方面进行了思考研究。 相似文献
79.
根据Pegg-Barnett 相位定义,计算了一类叠加相干态的相位概率分布函数,并进行了数值模拟. 结果表明,该量子态的相位概率分布受到叠加参数和相位参数的调制. 相似文献
80.
依托青海大学教育教学研究课题,对当前普通高校公共体育课程改革的理论及青海大学体育课程教学现状进行了分析,认为青海大学体育教学改革应依据《全国普通高等学校体育课程教学指导纲要》及现代高校课程改革新理论,借鉴国内著名高校体育课程改革成功经验,结合青海大学体育工作具体特点,构建课内外一体化整体课程教学体系,是培养大学生体育锻炼习惯和养成终身体育意识的有效途径,也是今后学校体育教学改革发展的方向。 相似文献