具有一阶奇异性解的函数组的边值问题与奇异积分方程组

在光滑封闭曲线条件下，讨论了具有一阶奇性解的函数组的边值问题与奇异积分方程组的解法。推广了原有的结果．     

家用冰箱部件模型的分析与建模思想

依据自顶向下的软件开发方法，从用户对冰箱动态仿真软件的功能需要入手，分析了冰箱整机及各个部件在不同时刻，不同工况下的动态运行特性，提出了各部件的建模思想及模型选取策略，根据当前仿真技术水平及硬件条件，认为压缩机采用稳态模型，蒸发器和冷凝器采用动态分相集中参数模型，毛细管采用稳态模型，箱体负荷计算采用传递函数模型比较合适，根据以上思想建立的冰箱仿真各个部件的模型，已成功地用于冰箱仿真软件的开发。     

Alternative splicing and expression of the insulin-like growth factor （IGF-1） gene in osteoblasts under mechanical stretch

Insulin-like growth factor 1 (IGF-1) promotes osteoblasts differentiation and bone formation, and its expression is induced by mechanical stretch, thus IGF-1 has been considered an effector molecule that links mechanical stimulation and local tissue responses. In this study, a mechanical stretching device was designed to apply physiological level static or cyclic stretching stimulation to osteoblasts. Different isoforms of IGF-1 mRNA were amplified by RT-PCR from the cells using respective primers and these amplified products were sequenced. An iso-form of IGF-1 splicing product was found to be selectively produced by osteoblasts under stretching stimulation. This IGF-1 isoform had identical sequence with the mechano growth factor (MGF) which was originally identified in muscle cells. Regulations of the expression of the liver-type IGF (L.IGF-1) and MGF in osteoblasts under stretch stimulation were further studied using semi-quantitative RT-PCR. Stretch stimulation was found to promot the expression of IGF-1 (L.IGF-1 and MGF), and for both isoforms expression was more effectively stimulated by cyclic stretch than static stretch. MGF was detected only in osteoblasts subjected to mechanical stretch, suggesting MGF was a stretch sensitive growth factor. Expression of MGF peaked earlier than that of L.IGF-1, which was similar to their regulation in muscle and suggested similar roles of MGF and L.IGF-1 in bone as in muscle cells. The functions of MGF and LIGF-1 in osteoblasts shall be established by further experimental studies.     

1-(4-甲基-6-烃基环己-3-烯羰基)吡咯烷-2-酮衍生物的质谱裂解研究

研究了5种1-(4-甲基-6-烃基环己-3-烯羰基)吡咯烷-2-酮衍生物的电子轰击质谱(EI-MS),从所得的质谱数据,探讨了在70 eV下该类化合物的碎片断裂机理.     

Genetic polymorphisms of milk epithelial mucin of yaks

Milk epithelial mucin (MUC1) of yaks was separated by SDS-polyacrylamide gel electrophoresis. A total of nine types of MUC1 were revealed in 427 yaks from five yak breeds including Maiwa yak, Jiulong yak, Tianzhu white yak, Qinghai yak and Tibetan yak. The molecular weights of MUC1 are from 163 kD to 208 kD, most of which are larger than those of bovine. Population genetic analysis shows that the gene frequency and genotype frequency of yak MUC1 differ among breeds, with relatively high gene heterozygosity. The five yak breeds studied fall into two groups according to their milk MUC1 gene frequency, suggesting that milk MUC1 exhibits specificities for local yak groups.     

对U检验法使用的探讨

本文就假设检验中U检验法的使用不慎而对检验效果的影响通过数学推导逆行了分析探讨。指出在总体均值的假设检验中,当检验时采用的总体方差不是其真值时,必会导致检验的势函数值发生变化,检验中犯第一、二类错误的概率增大,同时对总体均值进行区间估计的置信度也受到影响。因此,左进行生产或工程实验中,为提高检验效果,少犯错误,应尽可能正确地推定新生产工艺或工程变更后的总体方差,不要盲目、简单地套用U检验法的检验程序。如果新总体的方差不易推定,则应采用T检验法进行检验。     

河南西峡恐龙18srDNA片段质疑

按照ｒＤＮＡ的结构特点，将ＤＡ１８Ｓ１，７与其他８种生物的ｒＤＮＡ序列进行排列比较，结果表明这２个序列不是恐龙ｒＤＮＡ片段，ＤＡ１８Ｓ７看来更接近一种植物ｒＤＮＡ片段（与金虎尾的同源性达９４％以上），而ＤＡ１８Ｓ１与２种参与比较的真菌ｒＤＮＡ序列有很高的同源性（８８．３％和８９％），它们与脊椎动物ｒＤＮＡ的同源性分别只在６７．８％～７４．１％之间。     

齐齐哈尔市农业发展灰色分析

本文以齐齐哈尔市农业经济发展实际为背景,应用灰色系统理论对农业经济发展进行了系统分析,获得了许多有价值的信息,具有实际意义。     

合成药物盐酸洛非西定及其中间体的结构鉴定

本文用ＩＲ，ＮＭＲ，ＭＳ及ＵＶ四大谱对合成药物盐酸洛非西定的化学结构进行了研究，四大谱表明了该化合物与中间体的不同结构特征，确认了该化合物的化学结构。     

Species-specific differences in the mitogenic activity of heparin-binding growth factors in the sera of various mammals

Sera from different mammalian species displayed great differences in mitogenic activity, as measured by stimulation of DNA synthesis in BALB/c 3T3 cells (3T3 cells). Among the sera examined, fetal bovine serum was least active, and increasing activity was detected in calf serum, human serum, rat serum and mouse serum, in that order. Rat and mouse sera exhibited extremely high mitogenic activity with 3T3 cells, but when TIG-1 human fetal lung fibroblasts were used for the DNA assay instead, the activity levels of all of the sera were lower, and the differences between them were smaller. To determine the reasons for these differences, the heparin-binding growth factors in each serum were separated on a heparin affinity column. Five peaks of DNA-stimulating activity were obtained. Three of these were found in all sera examined, with both 3T3 cells and TIG-1 cells. Two other peaks were found only with 3T3 cells; one was peculiar to rat and mouse sera, with extremely high activity in the rat, and the other was specific to fetal serum. The dependence of the activity of these peaks on the cells used for the test was confirmed using normal rat lung fibroblasts and immortalized rat kidney cells. These findings adequately explain the species-specific differences in mitogenic activity of whole sera, and the variation in activity depending on the cells used for assay of DNA synthesis.