“浙技呼康散”防治肉鸡慢性呼吸道疾病试验

鸡的败血霉形体(MG)引起的慢性呼吸道疾病(CRD)严重影响家禽生长速度、屠体品质及成活率。本文叙述了浙技呼康散药物防治鸡慢性呼吸道疾病情况。该药物预防CRD能明显提高鸡成活率10％--20％,能在2—4无内控制病情,保证良好的屠体品质。通过试验确定浙技呼康散预防剂量为1g/羽粉剂,5ml/羽汤剂;治疗剂量2g/羽粉剂、10ml/羽汤剂。在应用中宜先煎汁饮之,渣拌料服用教果更好。     

上善若水济苍生——记著名脑神经疾病防治专家王文志教授

初识北京市神经外科研究所神经流行病学研究室主任、著名神经疾病防治专家王文志教授,恂恂平雅、淡泊宁静的气质给人一种沉稳、踏实、平易近人的感觉。随着对王文志主任的了解;一个心系大众、兢兢业业、时时惕厉自己,以预防控制疾病为己任的名医形象愈来愈清晰完整起来。笔者想起中医典籍《黄帝内经》中的一句话：“上医治未病;中医治欲病;下医治已病”,即医术最高明的医生并不是擅长治病的人,而是能够预防疾病发生的人。然而,许多人往往只看到为大众治愈疾病的医生,     

Bioinformatical study on the proteomics and evolution of SARS-CoV

A novel coronavirus has been identified as the causative agent of the severe acute respiratory syndrome (SARS). For all the SARS-CoV associated proteins derivated from the SARS-CoV genome, the physiochemical properties such as the molecular weight, isoelectric point and extinction coefficient of each protein were calculated. The transmembrane segments and subeellular localization (SubLoeation) prediction and conserved protein motifs search against database were employed to analyze the function of SARS-CoV proteins. Also, the homology protein sequence alignment and evolutionary distance matrix calculation between SARS-CoV associated proteins and the corresponding proteins of other coronaviruses were employed to identify the classification and phylogenetic relationship between SARS-CoV and other coronaviruses. The results showed that SARS-CoV is a novel coronavirus which is different from any of the three previously known groups of coronviruses, but it is closer to BoCoV and MHV than to other coronaviruses. This study is in aid of experimental determination of SARS-CoV proteomics and the development of antiviral vaccine.     

中国对虾暴发性流行病病原的免疫组织化学研究

对未感染中国对虾，实验感染暴发性流行病病原体后3h,12h,24h和36h及96h和136h，进行了系统的免疫组织化学研究，结果显示感染病虾的多种组织细胞呈阳性反应，说明暴发性流行病病原体具有广泛的宿主靶细胞，其中最易感的靶细胞是鳃、胃、后肠中具有合成和分泌几丁质动能的细胞，于暴发性流行病病原体侵入虾机体的体途径，使对虾致病和死亡的原因进行了探讨。