The three-fingered protein domain of the human genome

Extracellular domains of some cellular receptors expressed in the organisms at different levels of development belong to three-fingered protein (TFP) fold. The Homo sapiens genome encodes at least 45 genes containing from one to three TFP domains (TFPDs), namely diverse paralogues of the Ly6 gene, CD59 and the receptors of activins, bone morphogenetic proteins, Mullerian inhibiting substance and transforming growth factor-β. C4.4a and urokinase/plasminogen activatory receptor contain two and three TFPD repeats, respectively. These diverse proteins have a low overall sequence similarity with each other and their hydrophobicity levels vary to a considerable degree. It is suggested that sequence differentiation within the TFPD led to distinct groups of proteins whose attributes were optimized to fit both the physicochemical properties specific to their functional microenvironment and selective targeting of their highly diversified extracellular cofactors. Electronic supplementary material  The online version of this article (doi:) contains supplementary material, which is available to authorized users. Received 7 August 2008; accepted 29 August 2008     

中国古代循环演化思想探讨

循环演化观念是中国古代自然观的重要组成部分,对传统科学文化产生过广泛影响。本文系统考查了古代有关理论所反映的循环演化思想,初步分析了其基本内涵及科学价值,并指出了其局限性。     

人手柔性触觉感知特性

提出了一种新颖的基于弹性梁有效变形长度控制的柔性触觉感知再现方法,并研制了柔性触觉感知装置.通过在该柔性触觉装置上进行实验,对人手的柔性触觉感知特性进行了研究,得出一些结论.刚度越大,分辨率越低,随着刚度的增大,相比较的2个物体间需具有更大的刚度差异才能够分辨.当人们触摸物体时,习惯的次数为2～6次,按压频率主要分布在0.3～1.3 Hz.实验点的刚度越大越难记忆.连续感知的正确率要明显高于不连续感知的正确率.本实验方法简单有效,得出的实验结论不仅可用来改进触觉再现装置的设计,而且为触觉再现技术的研究提供了生理学依据.     

一类3-紧优双环网无限族

到给定顶点数的双环网的最小直径是图论和计算机工作者广泛研究的问题。虽然大多数双环网可以达到紧优,但仍然有一部分双环网不能达到。本文给出了一类3-紧优的双环网无限族。     

二十一世纪高校图书馆发展刍议

从强化图书馆员专业意识、增强开发利用信息资源意识、改变服务模式、提供高品质服务等方面,论述了图书馆员应如何迎接信息时代的挑战。     

On Collectivism-Individualism dimension in Chinese and Western Family Relationships

Western culture emphasizes on individualism,individual freedom and personal choice,while Chinese people put more emphasis on collectivism.Collectivism-Individualism value differences can also be reflected in Chinese and Western Family Relationships,which may sometimes lead to conflicts between the couples in the cross-cultural marriage and their families.     

闽粤赣客属地区族谱数据库建设构想

介绍了客家族谱的价值,分析了客家族谱数据库建设的必要性及现状,以闽粤赣客属地区族谱数据库建设为例,提出了客家族谱数据库建设构想。     

南社成员程善之家世、生平考述

皖南歙县程氏家族是清代颇负盛名的簪缨仕宦、世代书香之家,其后人程善之不仅是南社成员,还是同盟会会员。上世纪初他在扬州任教;辛亥革命中追随孙中山,任大元帅府评议;二次革命失败后,回扬州继续从事教育事业。1928年起主笔《新江苏报》,直至逝世;"九·一八"后曾积极进行抗战宣传。他喜好佛学,但亦积极进行文学创作,作为南社社员,他的诗、词、小说都颇有影响。然而关于程善之的家世、生平却很少有人谈及,现就其家世、生平作一简单的考述。     

上市公司家族控制对代理成本影响的实证分析

以沪深300家家族控股上市公司为研究样本,建立家族控制对代理成本影响的分析模型,实证分析结果表明:家族持股比例与代理成本呈显著的负相关关系;家族成员担任董事长或总经理有利于降低代理成本;家族董事对代理成本的影响不明显。