四卡问题的新视角——社会契约理论

Cosmides所提出的社会契约理论表明,人的推理能力具有领域特殊性的和内容依赖性。这不仅挑战了传统的推理假设,更以一种超越常规的方式促进了心理学特别是认知和发展心理学的发展。     

构建以职业生涯需求为主导的就业指导体系

大学生处于职业生涯发展的探索期,其职业发展既有理想的成分,又不得不考虑现实条件的限制.因此,大学生的职业生涯发展有其特殊的需求.针对大学生职业生涯发展的特殊需求,开展全程化就业指导,是构建当前高校就业指导体系的有效策略.     

做好导读工作 提高大学生人文素养

阐述了培养大学生人文素养的必要性,分析了大学生阅读的现状,指出高校图书馆应利用馆藏资源做好导读工作,以提高大学生人文素养.     

浅议大学生利用图书馆的3个阶段和对应的阅读指导

探讨了大学生利用图书馆的3个阶段及不同阶段对图书馆的不同需求,根据不同阶段提出了相应的阅读指导措施。     

以经典魅力引导学生前行

马克思主义经典著作,既是一座思想高峰,又是一座思想宝库,具有无穷的魅力。感受经典魅力,不仅可以使学生更好地理解和掌握马克思主义基本原理,深化对中国特色社会主义理论体系的理解,而且可以使人们受到良好的知识营养、思维训练和道德熏陶。因此,如何在教学中展现经典魅力并为大学生所接受,就成为经典教学的重要任务。为此,笔者结合自己的教学体会,从马克思主义经典著作的魅力,如何以经典魅力引导学生前行,教学效果这三方面谈一下自己的体会,以供大家参考和指正。     

Dynamic Niching Genetic Algorithm with Data Attraction for Automatic Clustering

A genetic clustering algorithm was developed based on dynamic niching with data attraction. The algorithm uses the concept of Coulomb attraction to model the attraction between data points. Then, the niches with data attraction are dynamically identified in each generation to automatically evolve the optimal number of clusters as well as the cluster centers of the data set without using cluster validity functions or a variance-covariance matrix. Therefore, this clustering scheme does not need to pre-specify the number of clusters as in existing methods. Several data sets with widely varying characteristics are used to demonstrate the superiority of this algorithm. Experimental results show that the performance of this clustering algorithm is high, effective, and flexible.     

Prediction of sites under adaptive evolution in flavin-containing monooxygenases: Selection pattern revisited

Flavin-containing monooxygenase (FMO), like cytochrome P450 (CYP), is a monooxygenase that uses the reducing equivalents of NADPH to reduce one atom of molecular oxygen to water, while the other atom is used to oxidize the substrate. Recently, it was shown that some CYP isoforms have been subject to positive selection. However, it is unknown whether the highly conserved phase I detoxification enzyme, FMO, has undergone similar positive Darwinian selection. We used maximum-likelihood models of codon substitution, evolutionary fingerprinting, and cross species comparison to investigate the occurrence of adaptive evolution in FMO sequences. We used recent genomic data from a range of species, including vertebrates and invertebrates. We present the evidence for the occurrence of adaptive evolution in mammalian FMO 3, 4, 5, and fugu FMOs but not in mammalian FMO 1, FMO 2, frog FMOs, other fish FMOs and invertebrate FMOs. The sites under adaptive evolution were significantly associated with the insertion domain in mammalian FMO 5. We identified specific amino acid sites in FMOs 3–5 that are likely targets for selection based on the patterns of parallel amino acid change. The most likely role of adaptive evolution is the repair of mutations that permitted optimal NADP+ binding and improved catalytic efficiency. The occurrence of positive selection during the evolution of phase I detoxification enzymes such as FMOs 3–5 and fugu FMO suggests the occurrence of both high selection pressure acting on species within their unique habitats and significant changes in intensity and direction (forms of xenobiotics and drugs) resulting from changes in microhabitat and food.     

泛函微分方程解的唯一性和渐近性

泛函微分方程的渐进理论作为泛函微分方程定性理论的一部分,在最近30年有了迅速的发展,广泛的应用背景是促使这一理论迅速发展的基础.本文结合时滞泛函微分方程的研究现状,对泛函微分方程解的唯一性和渐进性问题进行了分析.     

“双师”结构教师队伍激励机制的研究

高职教育的人才培养目标决定了高职院校教师队伍建设必然走上一条“双师”结构之路。探索一种包含有效的诱导因素、明确的行为导向、合理的奖惩幅度在内的“双师”结构教师队伍激励机制非常重要，其合理的激励机制是“双师”结构教师队伍建设的核心保障，统一明确的行为导向则是建立激励机制的关键。     

对大学生休闲辅导的思考

休闲辅导是指帮助学生确立正确的休闲观念和态度,获得必要的休闲知识和技能,以及学会安排有益的休闲活动方式,从而使自己获得充实而丰富的休闲生活,发展自己的才能与个性。休闲辅导是促进人的全面发展的重要手段,休闲辅导有助于消除目前大学生休闲中存在的问题。辅导大学生休闲活动要把握健康休闲活动的标准,明确大学生休闲辅导的目标,选择适宜的休闲活动内容,遵循大学生休闲活动的原则,拓宽大学生休闲辅导的途径。