Regulation of BMP4 on the proliferation and differentiation in SVZa neural stem cells

The neural stem cells in the anterior subventricular zone (SVZa) mainly generate the progenitors that will differentiate into neurons, and along a highly circumscribed migratory access Rostral migratory stream (RMS), they migrate to the olfactory bulbs (OB). To understand the effects of BMPs on SVZa neural stem cells, in this study BMP4 at various concentrations was used to induce SVZa neural stem cells, and the living cell labeling using BMP4 promotor conjugated with red fluorescence protein showed the expression of BMP4 dynamically. The results demonstrated that low BMP4 doses (1-5 ng/mL) promoted while high doses (10-100 ng/mL) inhibited the proliferation of SVZa neural stem cells, and BMP4 promotedneuron differentiation in the early stage (1-3 d), howeverm, it inhibited the neuron commitment after 4 d. Noggin, the antagonist of BMP4, blocked the physiological effects of BMP4. In OB, BMP4 is mainly to accelerate the progenitors to withdraw from the cell cycle and trigger the differentiation, and in RMS, it promotes the proliferation of committed progenitors and not differentiation, further in SVZa, BMP4 enhances astrocyte commitment.     

加速科技进步促进"红三角"经济繁荣

当今社会,科技进步对经济增长的影响越来越深远．实现“红三角”经济繁荣,必须充分重视科技进步对经济增长的促进作用．     

须条与长丝间距对Sirofil成纱结构性能的影响

分析了Sirofil纺纱过程中“V”形区的动态变化及粗纱须条与长丝间距大小对“V”形区形状和单纱受力的影响,认为间距增大会使“V”形区夹角增大、单纱段长度变长,并以此为依据,保持其他工艺参数不变,改变粗纱与长丝间距大小,试纺Sirofil纱,通过理论分析和实验比较讨论间距大小对Sirofil成纱结构性能的影响。结果表明：随着间距增大,成纱直径系数趋小、毛羽减少、强伸性与条干均呈非单调性变化;综合考虑成纱结构和性能,在其他参数相同时,Sirofil最佳成纱间距为12～16mm。     

Magnetic fabrics in fault-related fold and its relation with finite strain: an example from Mingjiang thrust structures in Western Sichuan

The anisotropy of magnetic susceptibility (AMS) is a quick, effective and sensitive technique used to measure the weakly deformed sedimentary rocks, and also a reliable method to reveal the deforming mechanisms of fault-related folds. In Longmenshan front belt, a typical cross-section of fault-related folds is chosen to study the AMS. A total of 224 oriented specimens have been drilled at 23 different sampling sites which were distributed at the key structural positions of this structural section developed in the Xujiahe formation of the upper Triassic. Six elementary types of magnetic fabrics are recognized and established through this AMS study: 1) a sedimentary fabric; 2) an initial deformation fabric; 3) a pencil structure fabric; 4) a weak cleavage fabric; 5) a strong cleavage fabric; 6) a stretching lineation fabric. It has been found that most of magnetic fabrics are characterized by fabrics of weak deformation which belong to the pure-shear results of a pre-folding layer parallel shortening (LPS). In the fault-bend fold, almost all magnetic fabrics are the initial deformation fabrics of weak deformation, and denote that the deformation in the forelimb is stronger than that in the backlimb and no finite strain is shown in the footwall. While in the fault-propagation fold， finite strains are concentrated in the trishear zone where magnetic fabric results are approximately consistent with the estimated consequences of the kinematic model. The tectonic stress field indicated by the magnetic fabrics is basically the same along the whole structural section and shows a NW to SE compression and shortening which is accordant with the regional compressive stress field of the Longmenshan fold-thrust belt.     

黄河大柳树生态经济区老灌区节水潜力综合分析

建设大柳树生态经济区是黄河黑山峡河段开发的主要任务,长期以来,围绕黄河流域突出的水资源供需矛盾,引起了不同学者和有关部门对大柳树生态经济区建设的学术技术争议.结合生态经济区水资源条件,以黄河大柳树生态经济区老灌区节水潜力为主线,系统分析了影响节水潜力的主要因素和敏感性.结果表明,通过输水工程改造、种植结构调整、田间改造、井渠结合、运行管理等方面的节水努力,老灌区节水量为13.18×108～22.69×108 m3,有水资源条件支撑了大柳树生态经济区的建设与开发.     

各向同性Gent-Thomas材料中空穴生成的突变性

研究了由均匀各向同性不可压缩Gent-Thomas材料组成的球体在给定表面拉伸死载荷作用下的球对称变形问题.得到了描述球体内部空穴生成和增长的空穴分岔方程.证明了方程的平凡解支上存在唯一的分岔点,以及非平凡解在分岔点附近可以局部向左或向右分岔.特别地,当材料参数取某些值时,局部向右分岔的非平凡解对应于拉伸死载荷超过某临界值时,球体内部有空穴生成并连续增长;而局部向左分岔的非平凡解支上还存在一个二次转向分岔点,在这种情形下,当拉伸死载荷还未超过临界值时,球体内部便有一个半径相对较大的空穴生成,这与其他各向同性不可压缩超弹性材料有明显的不同.同时给出了相应的数值算例.     

开采扰动区(EDZ)内层状围岩变尺度损伤及失稳预计实验及综合分析

在地下开采中常遇到层裂影响围岩力学行为,考虑到安全支护载荷及衍生动力灾害的可能性及工程应用,基于现场工程调查和室内多尺度煤岩动力破坏规律实验观察,建立了物理相似模型,完成了基于声发射(AE)的采空区覆岩变尺度损伤与断裂的模拟实验,对开采扰动区工作面周期来压(4个阶段)、围岩破裂与损伤的声发射特征参数(总事件与能率以及隐含的临界敏感性)等多元信息进行了综合比较,获得了老顶来压强度及支护阻力的定量化指标,这为工程现场EDZ内顶板大范围破断、围岩稳定性、破碎岩体失稳垮落等监测与控制提供依据。     

带保护区域的捕食-食饵模型平衡解的分歧与稳定性

研究了一类带保护区域的捕食-食饵模型正平衡解的分歧及稳定性.利用特征值分歧理论和谱分析的方法,分别以b、m为分歧参数,证明了系统在半平凡解(a,0)及(0,b)附近出现分歧现象,得到了该模型正平衡解存在的充分条件.同时运用线性特征值的扰动理论和分歧解的稳定性理论给出了该分歧解的稳定性,即系统在(a,0)附近的分歧解是无条件稳定的;当I>0时,系统在(0,b)附近的分歧解是稳定的,而当I<0时,分歧解是不稳定的,其中I是一个积分.     

长江经济带协调发展模式及机制创新

阐述了长江经济带协调发展的基本内涵。从发展模式和机制创新两个方面分析了促进长江经济带协调发展的思路:提出非均衡协调发展模式;实施培育和增强区域竞争力的区域政策,提高区域生产率及竞争力;建立和完善7方面的机制创新。     

卫星遥感资料在潮间带地形和漫滩计算中的应用

提出了利用卫星遥感资料计算潮间带地形和漫滩的方法：选取一组不同潮位的卫星遥感图像，提取潮间带遥感淹水线，由遥感淹水线和数值模式结合推算潮间带地形，将推算的地形用于海水漫滩计算，并用遥感淹水线检验漫滩计算结果.利用该方法，由Landsat 卫星图像提取了我国湛江港潮间带淹水线信息，计算了湛江港潮间带地形和漫滩.