An approximate analytical solution to the ultrafiltration profile in a hemodialysis process between parallel porous plates

In a hemodialysis process, the blood that runs through straight channels exchanges substances with the dialysate through a semi-permeable membrane. The waste products, such as urea and creatinine, are therefore removed from the plasma by the membrane. In the analysis of this process, determination of the ultra-filtration profile along the porous membrane surface remains a difficult problem. In this work, an analytical solution to the derivation of such a profile was detailed, and the feasibility of this solution was discussed. The ultra-filtration profile was found to be in a cosine shape.     

一类具有年龄结构的竞争系统的最优输入率控制

研究一类具有年龄结构的竞争系统的最优输入率控制问题．利用特征线法给出了解对控制变量的连续依赖性定理，利用法锥概念和共轭方程导出了最优性条件．所得结果可以为非线性的竞争系统最优控制问题提供必要的理论基础．     

Ethanol and the benzodiazepine-GABA receptor-ionophore complex

Summary Ethanol has a pharmacological profile similar to that of classes of drugs like benzodiazepines and barbiturates, which enhance GABAergic transmission in the mammalian CNS. Several lines of behavioral, electrophysiological and biochemical studies suggest that ethanol may bring about most of its effects by enhancing GABAergic transmission. Recently, ethanol at relevant pharmacological concentrations has been shown to enhance GABA-induced³⁶Cl-fluxes in cultured spinal cord neurons, synaptoneurosomes and microsacs. These enhancing effects of ethanol were blocked by GABA antagonists. Ro15-4513, an azido analogue of classical BZ antagonist Ro15-1788, reversed most of the behavioral effects of ethanol and other effects involving³⁶Cl-flux studies. The studies summarized below indicate that most of the pharmacological effects of ethanol can be related to its effects on GABAergic transmission.     

Exact inference for two exponential populations with competing risks data

In a reliability comparative test, the joint censoring model is usually adopted to evaluate the performances of units with the same facility. However, most researchers ignore the pos- sibility that there is more than one factor for the failure when a test unit fails. To solve this problem, we consider a joint Type-II hybrid censoring model for the analysis of exponential competing failure data. Based on the maximum likelihood theory, we compute the maximum likelihood estimators （MLEs） of parameters and then obtain the condition ensuring MLEs existence for every unknown parameter. Then we derive the conditional exact distributions and corresponding moment properties for parameters by the moment generating function （MGF）. A Monte-Carlo simulation is conducted to compare the performances of different ways. And finally, we conduct a numerical example to illustrate the proposed method.     

多重网络中的创意扩散模型研究

基于线上线下多种渠道的创意扩散研究是企业管理的新兴研究热点之一.为此,引入多重网络理论与传播动力学理论,考虑工作中线下沟通、工作中通过企业社交媒体在线沟通及非工作时间电子沟通三种渠道,构建多种渠道构成的多重网络中的创意扩散模型.研究创意在多重网络中持续扩散的阈值条件,并对创意在多重网络中的扩散过程进行仿真实验.结果表明:1)当员工在单位时间内通过以上各渠道沟通的平均次数较接近时,在多重网络中创意扩散的速度较快,创意扩散的范围较广;2)与匀质网络相比,当非工作时间电子沟通子网络是无标度网络时,在多重网络中创意扩散的速度较快,扩散的范围较广;3)增大子网络层间创意扩散的相互促进作用对整个多重网络中创意的有效扩散有积极影响.     

关于混凝土衬砌渠道遭受冻害的探究

山东气候是海洋性季风气候,属于季节性冻土地区,大部分地区在冬季存在混凝土衬砌渠道冻胀破坏问题。文章主要分析了混凝土衬砌渠道被冻胀破坏的几种形式和具体的成因,并提出防治冻害的措施。     

相关Nakagami衰落信道下SC/MRC系统性能分析

多输入多输出（multiple-input multiple-output,MIMO）系统的发射端天线选择是从多根天线中选择其中信道状况最好的一根用于发射信号,可减少所需要的射频链的个数,从而降低系统的复杂度及实现成本.该文研究发射端进行天线选择、接收端采用最大比合并接收的系统在相关Nakagami衰落信道下的性能,推导出输出信噪比的分布密度函数,进而给出了精确的误比特率（BER）公式,该表达式仅包含非常简单的函数,易于计算.     

基于竞争失效的数控系统PCB性能退化可靠性建模技术

为全面、客观、准确地评估数控系统PCB在外部环境应力和内部线路结构作用下的可靠性水平,验证其是否满足数控系统可靠性设计的要求及其在实际工作环境中能否支持系统可靠的工作,以数控系统PCB为研究对象,从可靠性分析与评估中的核心和关键问题出发,在综述PCB失效机理和退化失效分析的基础上,提出了一种基于多失效机理竞争的数控系统PCB可靠性统计模型的构建思路,结合不同失效机理下的数控系统PCB可靠性分析模型,分析失效机理间的相关性,并通过试验数据量化各失效机理在竞争失效模型中的权重,最终建立数控系统PCB竞争失效可靠性模型,为准确地分析和预测数控系统PCB的可靠性提供了方法和途径。     

苦物质引起去甲肾上腺素预收缩的大鼠主动脉平滑肌舒张的作用机理研究

为研究苦物质舒张预收缩的大鼠胸主动脉平滑肌的作用机制,以测定肌张力为主要手段,结合多种细胞信号通路阻断剂研究了苦物质的作用通路.结果表明:苦物质对于去甲肾上腺素介导的大鼠胸主动脉的收缩具有高效、快速的舒张作用,此舒张作用与IP3受体和L型钙通道的阻断密切相关.故以氯喹和苦精为代表的苦物质因对血管平滑肌具有良好的舒张作用,有望成为针对高血压等血管相关疾病的新的治疗药物.