New partial skeleton of Homo habilis from Olduvai Gorge, Tanzania

A new partial skeleton of an adult hominid from lower Bed I (about 1.8 Myr ago), Olduvai Gorge, is described. This specimen's craniodental anatomy indicates attribution to Homo habilis, but its postcranial anatomy, including small body size and relatively long arms, is strikingly similar to that of some early Australopithecus individuals.     

Molecular forms of dopamine beta-hydroxylase in rat superior cervical ganglion and adrenal gland

Summary Dopamine beta-hydroxylase (DBH) enzyme activity was associated in rat superior cervical ganglion with tetrameric DBH-A (294,000 D) and dimeric DBH-B (147,000 D) and in rat adrenal gland with DBH-A and a novel molecular form of DBH, defined as DBH-C, with a molecular weight of 125,000 D. Pretreatment of the rats with cycloheximide markedly reduced DBH activity without altering the molecular heterogeneity.     

Chemotherapy of parasite infections.

Although several good antiparasitic agents are available, new drugs are needed for the treatment of diseases such as chloroquine-resistant malaria, Chagas' disease, leishmaniasis and filariasis. The 'semirational approach' should be the basis for their synthesis.     

Métaplasie épidermoïde de l'épithélium mammaire humain,en culture organotypique à long-terme

Summary Squamous metaplasia of the mammary epithelium was observed in human breast tissue maintained in long-term organ culture. The phenomenon occurred only in the synthetic medium 199 with Earle's salts. Insulin and/or glucose enrichment enhanced its occurrence.