金刚煤矿矸石山煤矸石自燃机理分析

通过对金刚煤矿矸石山各类煤矸石样的H2O2氧化升温速率实验、实气氧化升温速率实验研究和对矸石山各类煤矸石各种形态硫的定量分析,以探索金刚煤矿矸石山煤矸石的自燃发火机理,从分析可见金刚煤矿矸石山煤矸石中硫铁矿含量很高,而硫铁矿中FeS2被空气中的氧气氧化并释放出大量的热量。热量不断积累、蓄热,当热量蓄累到一定温度时,煤矸石中的挥发分析出并着火燃烧,从而导致矸石山煤矸石的自然。     

甲胺磷席夫碱及其金属配合物的合成与生物活性研究

合成了甲胺磷席夫碱及其Cu(Ⅱ）,Zn(Ⅱ),Ni(Ⅱ)配合物,对它们进行了元素分析和UV,IR测试,对配体进行了MS和1H NMR等结构表征,另外,还对化合物进行了杀灭棉铃虫活性及影响绿豆幼苗细胞存活率实验。     

内藏电动机形状对前向多叶离心风机性能的影响

为进一步提高风机产品的效率、降低噪声,对内藏电动机式前向多叶离心风机,用3种可伸缩套筒模拟内藏电动机进行了负机性能实验,利用5孔探针对叶轮出口流场进行了测试,并分析了内藏电动机引起风机性能变化的原因。研究结果表明,电动机长度、外径、头部倾角对风机性能和噪声有较大影响,而内藏电动机引起叶轮内部流动损失增大、叶轮水力效率降低是影响风机性能的主要原因。     

Sustainable Community Development: A Brief Introduction to the Multi-Modal Systems Method

There is still no agreement on the concept of sustainable development but, what was initially only seen as an equation of economic growth and protection of environment resources, has now began to include several other dimensions, such as the social, cultural, ethical, legal and political. However, this requires a scientific perspective capable of dealing with ethical and normative questions. The Multi-Modal Systems Method intends to tackle the sustainable issue in a total manner, based on a trans-disciplinary approach and on a method that makes possible practical applications in empirical contexts. This article presents an introduction to this method in the context of the sustainable development of communities.     

How Lemmings on Wheels Can Make a U-Turn Through Social Inclusion and Democracy

The challenge is (a) to balance both centralised control to preserve the global commons and (b) to involve people in policy making so that they feel culturally engaged and committed to the policy. Dictatorships and forms of World government from above to support the global commons are no more of an answer than forms of liberal democracy that do not engage people in between national elections. Passive voting does not help people in diverse democracies to engage in thinking through ‘if then scenarios’ about their social, economic and environmental future.     

Historical variations in δ 13 C leaf of herbarium specimens in the southwestern U.S.

The uncontrolled, global increase in atmospheric CO 2 concentration (ca 80 ppmv) and decline in δ 13 C air (ca 1.5%) since industrialization provide experimental boundary conditions by which to assess physiological response of vegetation. To examine consequences of these global atmospheric changes in the southwestern U.S., 350 specimens of Atriplex confertifolia, A. canescens, Ephedra viridis, Pinus edulis, P. flexilis, Juniperus scopulorum, and Quercus turbinella of precisely known age spanning the last 150 years were acquired from 9 herbaria. Cellulose analysis of δ 13 C plant and estimation of isotopic discrimination (Δ) permitted calculation of water-use efficiency (A/g). The δ 13 C plant chronologies of C 4 Atriplex spp. show some promise as a reliable proxy for δ 13 C air because their mean trends approximate the known δ 13 C air chronology. However, the high variability would necessitate multiple samples at any time period to accurately represent the mean. The generally increasing A/g trends of the 5 C 3 species are particularly pronounced for P. edulis and, after the 1950s, for J. scopulorum, but less evident for P. flexilis, E. viridis, and Q. turbinella, evidencing possible differences in species response to rising CO 2 concentrations. The trends are statistically noisy, however, possibly due to complex microclimates, extreme seasonality, and great interannual variability typical of the southwestern U.S. Herbarium specimens, at least in the Southwest, may be less useful for precise detection of direct CO 2 effects on plant physiology than tree rings, where the variability can be constrained to a single individual over time.     

The influence of salts on the inhibition of the respiration of baker's yeast by basic dyes

Résumé MgCl₂ et d'autres sels à des concentrations définies protègent la respiration de la levure de boulangerie contre l'action inhibitrice de colorants basiques.     

Structure of the insulin receptor ectodomain reveals a folded-over conformation

The insulin receptor is a phylogenetically ancient tyrosine kinase receptor found in organisms as primitive as cnidarians and insects. In higher organisms it is essential for glucose homeostasis, whereas the closely related insulin-like growth factor receptor (IGF-1R) is involved in normal growth and development. The insulin receptor is expressed in two isoforms, IR-A and IR-B; the former also functions as a high-affinity receptor for IGF-II and is implicated, along with IGF-1R, in malignant transformation. Here we present the crystal structure at 3.8 A resolution of the IR-A ectodomain dimer, complexed with four Fabs from the monoclonal antibodies 83-7 and 83-14 (ref. 4), grown in the presence of a fragment of an insulin mimetic peptide. The structure reveals the domain arrangement in the disulphide-linked ectodomain dimer, showing that the insulin receptor adopts a folded-over conformation that places the ligand-binding regions in juxtaposition. This arrangement is very different from previous models. It shows that the two L1 domains are on opposite sides of the dimer, too far apart to allow insulin to bind both L1 domains simultaneously as previously proposed. Instead, the structure implicates the carboxy-terminal surface of the first fibronectin type III domain as the second binding site involved in high-affinity binding.     

Nanog promotes transfer of pluripotency after cell fusion

Through cell fusion, embryonic stem (ES) cells can erase the developmental programming of differentiated cell nuclei and impose pluripotency. Molecules that mediate this conversion should be identifiable in ES cells. One candidate is the variant homeodomain protein Nanog, which has the capacity to entrain undifferentiated ES cell propagation. Here we report that in fusions between ES cells and neural stem (NS) cells, increased levels of Nanog stimulate pluripotent gene activation from the somatic cell genome and enable an up to 200-fold increase in the recovery of hybrid colonies, all of which show ES cell characteristics. Nanog also improves hybrid yield when thymocytes or fibroblasts are fused to ES cells; however, fewer colonies are obtained than from ES x NS cell fusions, consistent with a hierarchical susceptibility to reprogramming among somatic cell types. Notably, for NS x ES cell fusions elevated Nanog enables primary hybrids to develop into ES cell colonies with identical frequency to homotypic ES x ES fusion products. This means that in hybrids, increased Nanog is sufficient for the NS cell epigenome to be reset completely to a state of pluripotency. We conclude that Nanog can orchestrate ES cell machinery to instate pluripotency with an efficiency of up to 100% depending on the differentiation status of the somatic cell.     

Hydroxyproline-rich glycoproteins in plant reproductive tissues: structure, functions and regulation

The plant reproductive process of pollination involves a series of interactions between the male gametophyte (the pollen grain or pollen tube) and extracellular matrix (ECM) molecules secreted by different cell types along the pollen tube growth pathway in the female organ, the pistil. These interactions are believed to signal and regulate the pollen tube growth process to effect successful delivery of the sperm cells to the ovules where fertilization takes place. Hydroxyproline-rich glycoproteins secreted by plant cells are believed to play a broad range of functions, ranging from providing structural integrity to mediating cell-cell interactions and communication. The pistil and pollen tube ECM is enriched in these highly glycosylated proteins. Our discussions here will focus on a number of these proteins for which most information has been available, from Nicotiana tabacum, its self-incompatible relative N. alata, and Zea mays. In addition, the regulation of the synthesis and glyco-modification of one of these proteins, TTS (transmitting tissue-specific) protein from N. tabacum will be discussed in the light of how differential glycosylation may be used to regulate molecular interactions within the ECM.