The transulfuration of sulfinates by polysulfides

Riassunto È stato dimostrato che la transulfurazione che consegue alla incubazione dei solfinati con zolfo ed un composto tiolico è dovuta in parte alla produzione di un polisolfuro organico, formato dal tiolo e zolfo, ed in parte al polisolfuro inorganico, formato dalla decomposizione di quello organico. L'entità della transulfurazione prodotta direttamente dal polisolfuro organico varia con il tipo di polisolfuro e dipende dalla sua stabilità nelle condizioni usate.     

Teratogenic effects induced in tail ofBufo arenarum tadpoles following treatment with carcinogens

Riassunto Si descrivono gli effetti teratogeni indotti nella coda del girino delBufo arenarum in uno stadio premetamorfosico, come conseguenza dell'impianto di cristalli di idrocarburi cancerigeni. Tanto il MC come il BP o il DMBA producono alette sopranumerarie che ripetono le strutture istologiche delle alette normali; ed inoltre il DMBA induce la formazione di una seconda notocorda parallela alla normale.

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Career investigator of Argentine CNICT.

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Fellow of Argentine CNICT.     

Stimulation of pyruvate carboxylation by gastric secretagogues

Summary Pyruvate carboxylation was stimulated by 2 gastric secretagogues, histamine and dibutyryl cyclic AMP, and by butyrate. Thiocyanate, an inhibitor of acid secretion, produced a slight decrease. Avidin significantly reduced acid secretion and this effect was overcome by biotin and oxalacetate. The results suggest that carboxylation of pyruvate is one of the reactions controlling oxidative metabolism and acid secretion in toad gastric mucosa.This investigation was supported by Consejo de Desarrollo Científico y Humanístico de la Universidad del Zulia, and by CONICIT Grant S1-0455.     

On the synthesis of poliovirus RNA at supraoptimal temperatures

Riassunto La scarsa incorporazione di precursori dello ARN in cellule infette da poliovirus ed incubate a 41,5°C è dovuta ad una inibizione della sintesi dello ARN virale più che non ad una sua digestione ad opera di nucleasi.

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Work supported by a Grant of Consiglio Nazionale delle Ricerche, Rome.     

新一代开放系统及互操作性研究

经历 2 0世纪 90年代的持续实践 ,采用“开放系统”的思想来集成大型的计算机系统已成为技术界不争的事实。然而 ,技术的发展使得传统的开放系统面临严峻的挑战 ,需要新的标准、技术来使开放系统体现高度的智能协作性及移动性。基于完善的开放系统的实际形成有赖于“互操作性”的实现这一原因 ,以互操作性为研究对象 ,以移动agent为研究工具 ,探讨了新一代开放系统实现机制以及未来发展的前景。     

Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans

Wild isolates of Caenorhabditis elegans can feed either alone or in groups. This natural variation in behaviour is associated with a single residue difference in NPR-1, a predicted G-protein-coupled neuropeptide receptor related to Neuropeptide Y receptors. Here we show that the NPR-1 isoform associated with solitary feeding acts in neurons exposed to the body fluid to inhibit social feeding. Furthermore, suppressing the activity of these neurons, called AQR, PQR and URX, using an activated K(+) channel, inhibits social feeding. NPR-1 activity in AQR, PQR and URX neurons seems to suppress social feeding by antagonizing signalling through a cyclic GMP-gated ion channel encoded by tax-2 and tax-4. We show that mutations in tax-2 or tax-4 disrupt social feeding, and that tax-4 is required in several neurons for social feeding, including one or more of AQR, PQR and URX. The AQR, PQR and URX neurons are unusual in C. elegans because they are directly exposed to the pseudocoelomic body fluid. Our data suggest a model in which these neurons integrate antagonistic signals to control the choice between social and solitary feeding behaviour.