Combining multiple forecasts given multiple objectives

This paper is concerned with expanding the decision support capabilities of computerized forecasting systems. The expansion allows for the systematic combination of multiple forecasts and the explicit consideration of multiple objectives in the forecast selection process. The methodology used is multiple objective linear programming. Selecting an individual forecast based upon a single objective may not make the best use of available information for a variety of reasons. Combined forecasts may provide a better fit with respect to a single objective than any individual forecast. Even if an individual forecast does provide a good fit with respect to a single objective, a combined forecast may provide a better fit with respect to multiple objectives. An example is used to illustrate the expanded decision support system, its outputs and their properties.     

The effects of intraventricular injection of 6-hydroxydopamine on the sleep of kittens during development]

Intraventricular injection of 6-hydroxydopamine does not modify the states of alertness in the Kitten, if it is performed in the first week of postnatal life. At three weeks of age, it induces the same sleep impairments as those observed in the adult Cat. Therefore, in the immediate postnatal period, sleep control is not achieved through the monoaminergic systems.     

delta-9-Tetrahydrocannabinol (THC) inhibition of the membrane transport system for thymidine]

THC decreases 3H-thymidine uptake within 15 sec. after addition of the drug to the culture (L1210 murine lymphoma cells and human lymphocytes). Experiments performed at 0 degrees C indicate that THC has no action on thymidine binding to the carrier. THC in micromolar concentration inhibits DNA synthesis through a alteration of membrane configuration.     

Respiratory function of blood and relative weight of certain organs in two species of shrew: Crocidura russula and Suncus etruscus (Soricidae mammals)]

A high oxygen capacity combined with a low oxygen affinity and a large Bohr effect achieve a high oxygen transport capacity in small shrews. The high metabolic rate (Suncus estruscus: 100 to 350 ml O2/kg. min) can be explained by the combination of the favorable blood parameters with a high relative heart weight (1,2% of body weight) and heart frequencies of 1,000 to 1,350 per minute.