全文获取类型
收费全文 | 55556篇 |
免费 | 259篇 |
国内免费 | 544篇 |
专业分类
系统科学 | 1231篇 |
丛书文集 | 335篇 |
教育与普及 | 285篇 |
理论与方法论 | 535篇 |
现状及发展 | 32413篇 |
研究方法 | 695篇 |
综合类 | 18673篇 |
自然研究 | 2192篇 |
出版年
2013年 | 802篇 |
2012年 | 540篇 |
2011年 | 2578篇 |
2009年 | 611篇 |
2008年 | 753篇 |
2007年 | 818篇 |
2006年 | 956篇 |
2005年 | 1096篇 |
2004年 | 2340篇 |
2003年 | 1859篇 |
2002年 | 1534篇 |
2001年 | 1336篇 |
2000年 | 842篇 |
1999年 | 936篇 |
1998年 | 644篇 |
1997年 | 775篇 |
1996年 | 531篇 |
1994年 | 687篇 |
1993年 | 690篇 |
1992年 | 876篇 |
1991年 | 741篇 |
1990年 | 828篇 |
1989年 | 642篇 |
1988年 | 594篇 |
1987年 | 632篇 |
1986年 | 730篇 |
1985年 | 875篇 |
1984年 | 743篇 |
1983年 | 651篇 |
1982年 | 797篇 |
1981年 | 840篇 |
1980年 | 904篇 |
1979年 | 1411篇 |
1978年 | 1302篇 |
1977年 | 1264篇 |
1976年 | 1122篇 |
1975年 | 1109篇 |
1974年 | 1029篇 |
1973年 | 1228篇 |
1972年 | 1293篇 |
1971年 | 1334篇 |
1970年 | 1445篇 |
1969年 | 1300篇 |
1968年 | 1255篇 |
1967年 | 1127篇 |
1966年 | 929篇 |
1965年 | 779篇 |
1964年 | 499篇 |
1958年 | 605篇 |
1957年 | 516篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
71.
该文报道了所研制的具有AIN/TbFeCo/AIN/AI四层结构磁光光盘的动态性能测试结果.当记录信息位尺寸为1μm时,信息读出载噪比大于45dB,载噪比随盘片径向位置而异.文中根据测试结果,讨论了影响载噪比的诸因素. 相似文献
72.
光纤色散对OFDL器件功能的影响并不总能忽略。对OFDL陷波器,在现有器件水平下,由于色散ND只能达到30dB左右,远低于测量系统的限制(>55dB)。利用陷波器,也可以测量光纤色散、该方法具有步骤简便、对器件要求低、精度高等优点。 相似文献
73.
Growth hormone signal transduction 总被引:1,自引:0,他引:1
Growth hormone (GH) promotes animal growth by stimulating bone and cartilage cell proliferation, and influences carbohydrate and lipid metabolism. Some of these effects are brought about indirectly via somatomedin induction in hepatocytes, others by acting directly on the target cells. In either case, GH first binds to specific receptors on cells to trigger a sequence of biochemical events culminating in a biological response. Recently much has been learnt about the molecular structure of GH receptor, its binding to ligand, and the ensuing signal transduction events. 相似文献
74.
DNA fingerprinting transforms the art of cell authentication. 总被引:4,自引:0,他引:4
The increasing diversity of new cell cultures is seriously stretching the capabilities of traditional methods of identification. DNA fingerprinting is set to play an important role in increasing confidence in the authenticity of cultures in research and industry. 相似文献
75.
We recently reported on a linkage study within a Quarter Horse lineage segregating hyperkalaemic periodic paralysis (HYPP), an autosomal dominant condition showing potassium-induced attacks of skeletal muscle paralysis. HYPP co-segregated with the equine adult skeletal muscle sodium channel alpha subunit gene, the same gene that causes human HYPP. We now describe the Phe to Leu mutation in transmembrane domain IVS3 which courses the horse disease. This represents the first application of molecular genetics to an important horse disease, and the data will provide an opportunity for control or eradication of this condition. 相似文献
76.
对新球虫灵,喹乙醇,免健宝Ⅰ号,Ⅱ号配套复合饲料添加剂进行的幼兔饲养对比试验结果表明:以免健宝Ⅰ、Ⅱ号配套复合饲料添加剂联合效果为最佳,其它依次为单用兔健宝Ⅱ号、兔健宝Ⅰ号、喹乙醇,新球虫灵。而且兔健宝Ⅰ、Ⅱ号配套复合饲料添加剂有易混匀,简化配合饲料工序、节省饲料及增重快等优点。 相似文献
77.
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. 总被引:149,自引:0,他引:149
M M Shull I Ormsby A B Kier S Pawlowski R J Diebold M Yin R Allen C Sidman G Proetzel D Calvin 《Nature》1992,359(6397):693-699
Transforming growth factor-beta 1 (TGF-beta 1) is a multifunctional growth factor that has profound regulatory effects on many developmental and physiological processes. Disruption of the TGF-beta 1 gene by homologous recombination in murine embryonic stem cells enables mice to be generated that carry the disrupted allele. Animals homozygous for the mutated TGF-beta 1 allele show no gross developmental abnormalities, but about 20 days after birth they succumb to a wasting syndrome accompanied by a multifocal, mixed inflammatory cell response and tissue necrosis, leading to organ failure and death. TGF-beta 1-deficient mice may be valuable models for human immune and inflammatory disorders, including autoimmune diseases, transplant rejection and graft versus host reactions. 相似文献
78.
79.
Short alanine peptides, containing 16 or 17 residues, appear to form alpha-helices in aqueous solution. But the main spectroscopic analyses used on helical peptides (circular dichroism and nuclear magnetic resonance) cannot distinguish between an alpha-helix (in which the ith residue is hydrogen-bonded to residue i + 4; ref. 9) and the next most common peptide helix, the 3(10)-helix10 (i-->i + 3 hydrogen-bonding). To address this problem we have designed single and doubly spin-labelled analogues of alanine-based peptides in which the nitroxide spin label forms an unbranched side chain extending from the sulphur atom of a cysteine residue. Here we report the circular dichroism, Fourier-transform infrared and electron-spin resonance spectra of these peptides under helix-forming conditions. The infrared absorbance gives an amide I' band with a frequency that is substantially different from that observed for alpha-helices. The electron-spin resonance spectra of doubly labelled helices show that the ranking of distances between side chains, around a single turn (residues 4-8), is inconsistent with an alpha-helical structure. Our experiments suggest that the more likely peptide geometry is a 3(10)-helix. 相似文献
80.
本文研究了在不同pH值下吐温—80.Tritonx—100.SLS三种表面活性剂四—(对-三甲铵苯基)卟啉Soret带的影响。 相似文献