Preliminary observations of a bacteriophage infectingXenorhabdus luminescens (Enterobacteriaceae)

A bacteriophage infective toXenorhabdus luminescens, a bacterial symbiont of heterorhabditid nematodes, was recovered from insects that supported poor nematode development. Plaque tests showed the phage particles to be infective only to primary and not secondary colonies ofX. luminescens. The phage was not infective toX. nenatophilus primaries or secondaries. The bacteriophage particles ranged 80–90 nm in length, with the head ranging from 40 to 50 nm in diameter. Restriction analysis was performed on isolated bacteriophage DNA. This first report of a bacteriophage fromXenorhabdus species has pratical implications since it could be detrimental to cultures ofHeterorhabditis nematodes that are being produced throughout the world for the biological control of insects.     

Adenovirus type 12 infection of defined mouse-human hybrid cell clones

Summary Human adenovirus type 12 does not multiply in mouse cells; only viral T-antigen is detected. Mouse-human cell hybrid clones containing human chromosomes A3, B5, C7, C11, C12, D14, E17, F19 and F20, support synthesis of adenovirus DNA and capsid antigens.The hybrid clones used in these experiments were kindly supplied by Drs.Carlo Croce andHilary Koprowski of the Wistar Institute, Philadelphia, Pennsylvania. Supported by Grants from National Cancer Institute.     

The effects of cocaine in the production of cardiovascular anomalies inβ-Adrenoreceptor stimulated chick embryos

Summary Cocaine potentiates the effects of epinephrine and norepinephrine in terms of aortic arch malformation in embryonic chicks. Cocaine itself induces aortic arch malformations when administered in large doses.This study was supported by grant No. HL 18050, National Heart and Lung Institute, National Institutes of Health, Bethesda, Maryland.     

Bdelloid rotifers in Dominican amber: Evidence for parthenogenetic continuity

Recently discovered representatives of the Class Bdelloidea from Tertiary amber from the Dominican Republic represent the oldest known fossils of the Phylum Rotifera. Assuming that the fossil bdelloids had a similar mode of reproduction as present day members of the Class (apomictic thelytoky), then contrary to current thought, some lines of parthenogenetic organisms are not doomed to an early extinction and have evolved built-in mechanisms for genetic diversity.     

Additional studies on the effects of neonatal thymectomy and lactate dehydrogenase virus infection on mice

Zusammenfassung Die gegebenen Befunde lassen vermuten, dass neonatale Thymektomie und/oder Infektion mit LDH-Virus einen Effekt auf eine Anzahl von Faktoren wie LDH-Plasma-Spiegel, Gewichtserhöhung und Lebensdauer in Mäusen hervorrufen können. Der Virustiter im Plasma ist vom Zeitpunkt der Infektion abhängig.

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Supported by Public Health Service research grant No. 5 R01 CA05742-06 from the National Cancer Institute.     

Influence of diglycyl-glycine on the radiation sensitivity of catalase

Zusammenfassung Die Veränderung der Strahlenempfindlichkeit von Katalase durch Diglycyl-glycin wurde spektralphotometrisch untersucht. Die Bestrahlungsdosen variierten zwischen 0–2,7 × 10⁶ r. Der Schutzeffekt lässt sich durch einen Radikal-abfangenden Mechanismus erklären. Strahlenbiologische Folgerungen werden diskutiert.     

Inactivation of yeast glucose-6-P dehydrogenase by aspirin

Summary Glucose-6-P dehydrogenase is irreversibly inactivated by treatment with Na salts of aspirin. Kinetic data show that 1 molecule of aspirin reacts with each active unit when the enzyme is inactivated. The rate of inactivation is enhanced with increasing pH but is reduced in the presence of glucose-6-P or NADP⁺. Na salicylate fails to inactivate the enzyme.This work was supported by grant RR-8006 from the General Research Branch, Division of Research Resources, NIH (USA).     

Concerning the free amino acids in the hydroid tubularia

Résumé La composition de l'amine acide libre dans les deux espèces deTubularia a été examinée au moyen de la chromatographie. Les tissus d'hydranthe deT. crocea avaient 21 amines acides libres dont 18 ont été identifiées dans les hydrocauli et dans les hydranthes régénérés deT. crocea, 19 dans les hydranthes deT. spectabilis et 14 dans les hydrocauli deT. spectabilis. La différence principale entre les hydranthes et les hydrocauli réside dans la distribution de certaines taches non-identifiées qui apparurent dans les chromatogrammes developpés avec la ninhydrine et les réactifs pour les groupes des imidazoles, guanidines, ou sulfhydriles.

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Part of a dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy, Florida State University. Aided by a National Science Foundation Predoctoral Fellowship and a National Science Foundation Grant to Dr. C. B.Metz, Contribution number 122 from the Oceanographic Institute, Florida State University.