The heavy chain of human histocompatibility antigen HLA-B7 contains an immunoglobulin-like region.

The 88-residue fragment (ac-2) containing the second disulphide loop from HLA-B7 heavy chain is shown to have statistically significant homology with Ig constant domains, including both matches at invariant positions and conservative substitutions of structurally important residues. Thus, both the light chain (beta 2m) and a segment of the heavy chain of HLA antigens may be structurally and evolutionarily related to immunoglobulins.     

Synthesis of caerulein

Riassunto Viene riportata la sintesi della piroglutamilglutaminil-aspartil-tirosil(O-solfato)-treonil-glicil-triptofanil-metionil-aspartil-fenilalaninamide, un peptide identico per proprietà chimiche, fisiche e biologiche alla caeruleina.     

Technique d'inclusion et d'ultramicrotomie,destinée à l'étude du développement des organelles dans une cellule isolée

Summary (1) Control of cell orientation and knowledge of the plane of sectioning are indispensable (but generally ignored) requirements for studies of the development of cellular constituents. (2) A simple technique that meets these requirements for the electron microscope is given. (3) As applied toParamecium, it is shown that the ciliary complexes of the new gullet develop outside of the old one, and that invagination begins at the anterior end of the gullet anlage.

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Travail effectué dans le cadre d'une recherche faite en collaboration avec les Instituts d'Histologie et de Biophysique, grâce à une subvention de «Fritz Hoffmann-La Roche-Stiftung zur Förderung wissenschaftlicher Arbeitsgemeinschaften in der Schweiz».     

Method for the quantitative evaluation of platelet function in blood coagulation

Zusammenfassung Eine Methode zur Auswertung der funktionellen Plättchenaktivität wird beschrieben. Isolierte Plättchen in konstanter Zahl (300000/cu.mm) werden einem alle übrigen Gerinnungsfaktoren in konstanter Menge enthaltenden Substrat zugesetzt. Prozente können von den Gerinnungszeiten durch eine Eichkurve ermittelt werden.     

Studies of the differences of osmotic pressure between the aqueous humor and the serum in some species of animals

Riassunto L'autore ha eseguito determinazioni della pressione osmotica dell'U. Acqueo e siero in alcune specie animali col metodo diNiederl e Levy. In tutte le specie animali ha riscontrato sempre un'ipertonia dell'Acqueo rispetto al siero di circa 2m/M.Soltanto nella cavia l'acqueo è leggermente ipotonico in rapporto al siero. L'autore spiega questa eccezione con la deficienza di anioni (cloruri e bicarbonati riscontrata nell'acqueo di cavia).