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991.
Frustrations of fur-farmed mink 总被引:5,自引:0,他引:5
992.
Most interpretations of early hominin phylogeny recognize a single early to middle Pliocene ancestral lineage, best represented by Australopithecus afarensis, which gave rise to a radiation of taxa in the late Pliocene. Here we report on new fossils discovered west of Lake Turkana, Kenya, which differ markedly from those of contemporary A. afarensis, indicating that hominin taxonomic diversity extended back, well into the middle Pliocene. A 3.5 Myr-old cranium, showing a unique combination of derived facial and primitive neurocranial features, is assigned to a new genus of hominin. These findings point to an early diet-driven adaptive radiation, provide new insight on the association of hominin craniodental features, and have implications for our understanding of Plio-Pleistocene hominin phylogeny. 相似文献
993.
Nuclear fission modes and fragment mass asymmetries in a five-dimensional deformation space 总被引:1,自引:0,他引:1
Nuclei undergoing fission can be described by a multi-dimensional potential-energy surface that guides the nuclear shape evolution--from the ground state, through intermediate saddle points and finally to the configurations of separated fission fragments. Until now, calculations have lacked adequate exploration of the shape parameterization of sufficient dimensionality to yield features in the potential-energy surface (such as multiple minima, valleys, saddle points and ridges) that correspond to characteristic observables of the fission process. Here we calculate and analyse five-dimensional potential-energy landscapes based on a grid of 2,610,885 deformation points. We find that observed fission features--such as the distributions of fission fragment mass and kinetic energy, and the different energy thresholds for symmetric and asymmetric fission--are very closely related to topological features in the calculated five-dimensional energy landscapes. 相似文献
994.
Enhancement of the high-magnetic-field critical current density of superconducting MgB2 by proton irradiation 总被引:2,自引:0,他引:2
Bugoslavsky Y Cohen LF Perkins GK Polichetti M Tate TJ Gwilliam R Caplin AD 《Nature》2001,411(6837):561-563
Magnesium diboride, MgB2, has a relatively high superconducting transition temperature, placing it between the families of low- and high-temperature (copper oxide based) superconductors. Supercurrent flow in MgB2 is unhindered by grain boundaries, making it potentially attractive for technological applications in the temperature range 20-30 K. But in the bulk material, the critical current density (Jc) drops rapidly with increasing magnetic field strength. The magnitude and field dependence of the critical current are related to the presence of structural defects that can 'pin' the quantized magnetic vortices that permeate the material, and a lack of natural defects in MgB2 may be responsible for the rapid decline of Jc with increasing field strength. Here we show that modest levels of atomic disorder induced by proton irradiation enhance the pinning of vortices, thereby significantly increasing Jc at high field strengths. We anticipate that either chemical doping or mechanical processing should generate similar levels of disorder, and so achieve performance that is technologically attractive in an economically viable way. 相似文献
995.
The Earth's mantle 总被引:6,自引:0,他引:6
Seismological images of the Earth's mantle reveal three distinct changes in velocity structure, at depths of 410, 660 and 2,700 km. The first two are best explained by mineral phase transformations, whereas the third-the D" layer-probably reflects a change in chemical composition and thermal structure. Tomographic images of cold slabs in the lower mantle, the displacements of the 410-km and 660-km discontinuities around subduction zones, and the occurrence of small-scale heterogeneities in the lower mantle all indicate that subducted material penetrates the deep mantle, implying whole-mantle convection. In contrast, geochemical analyses of the basaltic products of mantle melting are frequently used to infer that mantle convection is layered, with the deeper mantle largely isolated from the upper mantle. We show that geochemical, seismological and heat-flow data are all consistent with whole-mantle convection provided that the observed heterogeneities are remnants of recycled oceanic and continental crust that make up about 16 and 0.3 per cent, respectively, of mantle volume. 相似文献
996.
Homo neanderthalensis has a unique combination of craniofacial features that are distinct from fossil and extant 'anatomically modern' Homo sapiens (modern humans). Morphological evidence, direct isotopic dates and fossil mitochondrial DNA from three Neanderthals indicate that the Neanderthals were a separate evolutionary lineage for at least 500,000 yr. However, it is unknown when and how Neanderthal craniofacial autapomorphies (unique, derived characters) emerged during ontogeny. Here we use computerized fossil reconstruction and geometric morphometrics to show that characteristic differences in cranial and mandibular shape between Neanderthals and modern humans arose very early during development, possibly prenatally, and were maintained throughout postnatal ontogeny. Postnatal differences in cranial ontogeny between the two taxa are characterized primarily by heterochronic modifications of a common spatial pattern of development. Evidence for early ontogenetic divergence together with evolutionary stasis of taxon-specific patterns of ontogeny is consistent with separation of Neanderthals and modern humans at the species level. 相似文献
997.
Late blight, caused by the oomycete plant pathogen Phytophthora infestans, is a devastating disease of potato and was responsible for epidemics that led to the Irish potato famine in 1845 (refs 1,2,3,4,5). Before the 1980s, worldwide populations of P. infestans were dominated by a single clonal lineage, the US-1 genotype or Ib mitochondrial DNA (mtDNA) haplotype, and sexual reproduction was not documented outside Mexico, the centre of diversity of the pathogen. Here we describe the amplification and sequencing of 100-base-pair fragments of DNA from the internal transcribed spacer region 2 from 28 historic herbarium samples including Irish and British samples collected between 1845 and 1847, confirming the identity of the pathogen. We amplified a variable region of mtDNA that is present in modern Ib haplotypes of P. infestans, but absent in the other known modern haplotypes (Ia, IIa and IIb). Lesions in samples tested were not caused by the Ib haplotype of P. infestans, and so theories that assume that the Ib haplotype is the ancestral strain need to be re-evaluated. Our data emphasize the importance of using historic specimens when making inferences about historic populations. 相似文献
998.
999.
Dinosaurian growth rates and bird origins 总被引:7,自引:0,他引:7
Dinosaurs, like other tetrapods, grew more quickly just after hatching than later in life. However, they did not grow like most other non-avian reptiles, which grow slowly and gradually through life. Rather, microscopic analyses of the long-bone tissues show that dinosaurs grew to their adult size relatively quickly, much as large birds and mammals do today. The first birds reduced their adult body size by shortening the phase of rapid growth common to their larger theropod dinosaur relatives. These changes in timing were primarily related not to physiological differences but to differences in growth strategy. 相似文献
1000.
Fernandez-Lopez S Kim HS Choi EC Delgado M Granja JR Khasanov A Kraehenbuehl K Long G Weinberger DA Wilcoxen KM Ghadiri MR 《Nature》2001,412(6845):452-455
The rapid emergence of bacterial infections that are resistant to many drugs underscores the need for new therapeutic agents. Here we report that six- and eight-residue cyclic d,l-alpha-peptides act preferentially on Gram-positive and/or Gram-negative bacterial membranes compared to mammalian cells, increase membrane permeability, collapse transmembrane ion potentials, and cause rapid cell death. The effectiveness of this class of materials as selective antibacterial agents is highlighted by the high efficacy observed against lethal methicillin-resistant Staphylococcus aureus infections in mice. Cyclic d,l-alpha-peptides are proteolytically stable, easy to synthesize, and can be derived from a potentially vast membrane-active sequence space. The unique abiotic structure of the cyclic peptides and their quick bactericidal action may also contribute to limit temporal acquirement of drug resistant bacteria. The low molecular weight d,l-alpha-peptides offer an attractive complement to the current arsenal of naturally derived antibiotics, and hold considerable potential in combating a variety of existing and emerging infectious diseases. 相似文献