羧基淀粉的制备及其吸附性能的研究

本文研究羧基淀粉的制备条件与吸附重金属离子的容量关系,并研究它的使用条件和性能。     

Trying times for human insulin.

The introduction of human insulin to treat diabetics seemed straightforward. What can account for the problems that have followed?     

上皮生长因子预防心脏术后心包粘连的实验及临床研究

目的探讨上皮生长因子(EGF)对心脏术后心包粘连的预防作用.方法术中对犬心包内喷洒上皮生长因子3个月后,观察心包粘连情况;选先天性心脏病、房缺及室缺病人40例,术中心包内喷洒上皮生长因子,术后6个月、12个月经CT检查,判定心包粘连、增厚结果.结果在动物实验和临床研究中,实验组粘连程度显著低于对照组(P<0.01).结论 EGF心包内应用有明显预防心脏术后心包粘连的作用.     

二氧化氯在炼油循环水中的杀菌除泥作用

采用强氧化剂二氧化氯对炼油循环水进行杀菌灭藻、除垢和减缓腐蚀现场试验研究 ,且对试验结果进行了分析 .结果表明 :稳定性二氧化氯可有效控制炼油循环水中微生物量 ,加药量约 1mg/L ,2 4h后杀菌率达 10 0 % ;同时减少粘泥在热交换设备上的形成 ,有效除去污垢 ,使缓蚀剂发挥作用 ,腐蚀速率明显减小 (小于 0 .1mm /a) ,循环水浊度小于 10mg/L ;加药量小于 1mg/L时其对有机磷水稳定剂的影响小 .     

Growth hormone signal transduction

Growth hormone (GH) promotes animal growth by stimulating bone and cartilage cell proliferation, and influences carbohydrate and lipid metabolism. Some of these effects are brought about indirectly via somatomedin induction in hepatocytes, others by acting directly on the target cells. In either case, GH first binds to specific receptors on cells to trigger a sequence of biochemical events culminating in a biological response. Recently much has been learnt about the molecular structure of GH receptor, its binding to ligand, and the ensuing signal transduction events.     

Periodic paralysis in quarter horses: a sodium channel mutation disseminated by selective breeding.

We recently reported on a linkage study within a Quarter Horse lineage segregating hyperkalaemic periodic paralysis (HYPP), an autosomal dominant condition showing potassium-induced attacks of skeletal muscle paralysis. HYPP co-segregated with the equine adult skeletal muscle sodium channel alpha subunit gene, the same gene that causes human HYPP. We now describe the Phe to Leu mutation in transmembrane domain IVS3 which courses the horse disease. This represents the first application of molecular genetics to an important horse disease, and the data will provide an opportunity for control or eradication of this condition.     

Short alanine-based peptides may form 3(10)-helices and not alpha-helices in aqueous solution.

Short alanine peptides, containing 16 or 17 residues, appear to form alpha-helices in aqueous solution. But the main spectroscopic analyses used on helical peptides (circular dichroism and nuclear magnetic resonance) cannot distinguish between an alpha-helix (in which the ith residue is hydrogen-bonded to residue i + 4; ref. 9) and the next most common peptide helix, the 3(10)-helix10 (i-->i + 3 hydrogen-bonding). To address this problem we have designed single and doubly spin-labelled analogues of alanine-based peptides in which the nitroxide spin label forms an unbranched side chain extending from the sulphur atom of a cysteine residue. Here we report the circular dichroism, Fourier-transform infrared and electron-spin resonance spectra of these peptides under helix-forming conditions. The infrared absorbance gives an amide I' band with a frequency that is substantially different from that observed for alpha-helices. The electron-spin resonance spectra of doubly labelled helices show that the ranking of distances between side chains, around a single turn (residues 4-8), is inconsistent with an alpha-helical structure. Our experiments suggest that the more likely peptide geometry is a 3(10)-helix.     

生物序列分析

这次演讲将回顾近 1 0多年来应用某些随机模型于生物序列分析的研究工作 .这些模型本身有很长的历史 ,可追溯到 3 0多年以前 ,尽管从那时起 ,这些模型已经产生了很多新的变种 .在生物序列分析中模型的作用是归总那些涉及到在生物信息学中已知的模体 (motif)或域 (domain)的信息 ,并且提供一种工具在另一序列片段中寻找模体或域的实例 (instance) .我们将逐步介绍模体模型 ,从非常简单的 ,非随机情况开始 ,进而是更复杂的情况 ,直至近来的关于模体的剖面隐马氏模型 .第二个例子是来自利用一个或两个物种的序列数据进行基因发现 ,其中广义隐马氏模型或广义成对 (pair)隐马氏模型已被证实非常有效     

ON THE OPTIIMAL REACTIONS ASSEMBLAGE OF COMPLEX REACTION SYSTEMS

In this paper, the author analyzes distinguishing features of complex reaction systems and single reversible reaction, and optimizes complex reaction systems starting from set theory.The method of constructing the optimal reactions assemblage and calculating the potential maximum equilibrium yield (PMEY) of objective products is proposed here. This paper points out clearly that the euqilibrium yield of objective products calculated by means of conventional method is the global equilibrium yield (GEY).It is not the thermodynamic constraint, and could be exceeded by observed yield of objective products; only PMEY is the thermodynamic constraint. It gives information on potential and possible optimal yield and thereby improving production. This paper also points out the way in which the real complex reaction system approached the optimal reactions assemblage. The new concept of PMEY and optimal reaction assemblage proposed by this Paper is universally applicable for the important complex reaction systems, such as the pyrolysis of alkane to produce ethylene, steam reforming of methane to produce syngas, production of formaldehyde from methanol, epoxidation of ethylene to produce ethylene oxide, hydrogenation of benzene to produce cyclohexane.