Zn_(0.85)Co_(0.15)O粉体Rietveld全谱拟合表征

通过Rietveld全谱拟合对采用陶瓷烧结法制备的zn0.85 Co0.15O粉体的结构参数和非结构参数进行了精修,即快又准。得到了zn0.85 Co0.15O的精确峰位、d值、晶格常数、密度和原子位置等结构信息。     

基于科学史分级的高中物理教学策略——以“天然放射现象 原子的结构”为例

以"天然放射现象原子的结构"一节为代表的当前高中物理课程的教材与教学中,对科学史的处理呈现出的是一种"杂糅"的状态。基于科学史分级的教学策略,应针对本节不同的教学内容,对相应的层次采取不同的侧重,重新进行教学设计。从而实现科学史故事与科学史的剥离,区分科学思想史与科学方法史、实现科学史观教育的整体与连续性。     

Pressure gradient evolution in the near-Earth magnetotail at the arrival of BBFs

Using in situ observations from THEMIS A, D and E during the 2008-2011 tail season, we present a statistical study of the evolution of pressure gradients in the near-Earth tail during bursty bulk flow （BBF） convection. We identified 138 substorm BBFs and 2,197 non-substorm BBFs for this study. We found that both the pressure and the Bz component of the magnetic field were enhanced at the arrival of BBFs at the spacecraft locations. We suggest that the increase of Bz during non-substorm BBFs is associated with flux pile-up. However, the much stronger enhancement of Bz during substorm BBFs implies the occurrence of magnetic field dipolarization which is caused by both the flux pile-up process and near-Earth current disruption. Furthermore, a bow-wave-like high pressure appears to be formed at the arrival of substorm BBFs, which is responsible for the formation of region-1-sense FACs. The azimuthal pressure gradient associated with the arrival of substorm BBFs lasts for about 5 min. The enhanced pressure gradient associated with the bow wave is caused by the braking and diversion of the Earthward flow in the inner plasma sheet. The results from this statistical study suggest that the braking and azimuthal diversion of BBFs may commonly create azimuthal pressure gradients, which are related to the forrnation of the FAC of the substorm current wedge.     

稻壳热解油及其酯化产物的GC/MS分析

以酸性树脂作为催化剂,采用CH3OH和C2H5OH分别对稻壳热解油(RHPO)进行催化酯化反应,用正己烷、CCl4、CS2、苯和CH2Cl2分别萃取酯化前后的稻壳热解油,并采用气相色谱/质谱(GC/MS)对稻壳热解油进行表征.结果表明,稻壳热解油在苯中的可溶性最好,但其可溶物中酯类成分含量较低;CH3OH对有机酸的酯化效果优于C2H5OH;在稻壳热解油所检测的成分中,酚类含量最高,其次为酮类和烃类.通过对酯化产物的分析,推测稻壳热解油中可能含有有机酸.     

儿童玩具的情感互动性设计研究

从儿童玩具的情感互动性入手,结合儿童认知发展理论对儿童玩具设计提出新 的要求.文章运用儿童心理学等相关理论对儿童玩具的设计进行研究,从而设计出真正有价值的、人性化的儿童玩具.     

基于贝叶斯网络的停车收费政策评价

应用K2算法和贝叶斯参数估计方法,进行了贝叶斯网络的结构和参数学习,建立了停车行为分析的贝叶斯网络。应用连接树传播算法推断停车费率影响下的停车开始时间、停车时长和停车场类型等选择行为的变化,预测停车收费政策的实施效果,评价政策的可行性.结果表明:随着停车费率的提高,停车者更趋向于选择短时间停车;对不同时段和不同停车场类型实施不均衡收费制度,即高峰停车费率大于非高峰停车费率,路内停车费率大于路外停车费率,可以促使停车者选择非高峰时段停车和路外停车.     

Structural mechanisms of the agrin–LRP4–MuSK signaling pathway in neuromuscular junction differentiation

The neuromuscular junction (NMJ) is the most extensively studied model of neuronal synaptogenesis. Acetylcholine receptor (AChR) clustering on the postsynaptic membrane is a cardinal event in the differentiation of NMJs. AChR clustering and postsynaptic differentiation is orchestrated by sophisticated interactions among three proteins: the neuron-secreted proteoglycan agrin, the co-receptor LRP4, and the muscle-specific receptor tyrosine kinase MuSK. LRP4 and MuSK act as scaffolds for multiple binding partners, resulting in a complex and dynamic network of interacting proteins that is required for AChR clustering. In this review, we discuss the structural basis for NMJ postsynaptic differentiation mediated by the agrin–LRP4–MuSK signaling pathway.     

乙酰肝素酶(HPSE)与肿瘤生长、转移关系的研究进展

目的:通过文献学习,了解乙酰肝素酶与肿瘤的生长和转移的关系。结论:1.乙酰肝素酶的表达(heparananse HPSE)通过降解硫酸乙酰肝素细胞(heparansulfate,HS)和降解硫酸乙酰肝素蛋白聚糖(heparansulfate proteoglycan,HSPG),破坏、改变细胞外基质(extracellular matrix,ECM)和基底膜(basement membranes,BM)结构,促进肿瘤细胞侵袭、转移。2.诱导血管的生成直接作用于内皮细胞以生芽方式促进血管生成,通过释放肿瘤微环境和ECM中储存的高活性的HS-bFGF复合物来诱发直接的血管反应,促进肿瘤的生长。乙酰肝素酶的表达是判断多种肿瘤预后的标记物之一。     

Ordered mesoporous tungsten oxide and titanium oxide composites and their photocatalytic degradation behavior

Highly ordered mesoporous WO3/TiO2 (MWTs) composite materials with tunable chemical compositions were obtained by a surfactant template-assisted evaporation-induced selfassembly (EISA) processes. The structure properties of the MWT materials were characterized by small angle XRD, TEM and N2 sorption. The resultant materials showed large amount of ordered mesopores and high chemical homogeneity. With increasing crystallinity degree, the order degrees of mesostructure turned worse gradually. The MWT hybrids exhibited excellent visible light response due to the addition of WO3 with narrow band gap. Photocatalytic performances of the MWT samples were determined by measuring the photo-degradation of rhodamine B dye and phenol under simulated solar light irradiation. The effect of material parameters such as surface area, crystallinity and chemical compositions in the binary heterostructured system on photocatalytic performance were discussed in details.     

探索和实践国际化专业化的知识产权管理和科技成果转化道路——上海生科院知产中心/上海盛知华知识产权服务有限公司知识产权转化的成功案例概述

中国科学院上海生命科学研究院知识产权与技术转移中心和在其基础上成立的上海盛知华知识产权服务有限公司是具有国际水平的、专业化的知识产权管理与技术转移机构。通过上海生科院知产中心／上海盛知华公司的专业化管理,涌现出了一批知识产权转化的成功案例：近年来多项技术成果向国内外企业转移转化,更重要的是其中多项技术成果实现了向世界制药巨头、农业巨头的技术许可。本文对上海生科院知产中心／盛知华公司的工作模式、成功案例进行了详细介绍和分析,探讨了提高我国知识产权管理水平和转化能力所面临的问题和解决的途径。