Thermoelectric power and carrier concentration of La2−xSrxCuO4(0.03 <x <0.17) single crystals

Thermoelectric power (S) measurements have been systematically investigated in high-quality La2-x-Srx-CuO4 single crystals with different Sr concentrations (x =0.03, 0.05, 0.07, 0.1, 0.12). In this doping range studied, S remains positive, and with the increase of Sr concentration,room-temperature thermoelectric power S (290 K) decreases.An empirical formula which presents a relationship between hole concentration P and room-temperature thermoelectric power S (290 K) is reported in this note. Based on the theory of metallic diffusion model, the experimental results are discussed.     

Modeling studies on the changes of the Subtropical High over the Western Pacific during the last 100 years

Intensity index series of Subtropical High over the Western Pacific was constructed according to modeling results by using of CCM3.6 atmospheric model with climatologically SST forcing for 30 years, and with observed SST forcing from 1900 to 2000. The index series constructed by modeling closely correlated to the observations for 1951-1999 (c.c. 0.72) and to the statistically reconstructed one for 1900-1950 (c.c. 0.51). The index series for 1900-1999 showed significant 80 a and 40 a periodicity. A minimum of persistence in seasonal variations of the index occurred in Autumn, which was called "Autumn Barrier". It may relate to the "Spring Barrier", found in the seasonal variations of SST over the Eastern Equatorial Pacific. The increasing trend shown in the index series for the 20th century may associate with the global warming caused by enhancement of greenhouse effect.     

Construction of multivalent DNA vaccines forMycobacterium tuberculosis and its immunogenicity

The coding regions of Ag85B MPT-64, and ESAT-6 secreted proteins were cloned initially into the eukaryotic expression vector pJW4303, then transformed to E. coli Top 10 strain for plasmid DNA extraction and further analysis. Plasmids containing the right insertion were sequenced to confirm their identity. COS7 cells were transfected with a mixture containing serially diluted plasmid DNA encoding three secreted proteins and Lipofectin (Gibco). The supernatants and pellets prepared from various cell lines were run on SDS-PAGE gel and the expression of these proteins in COS7 cells were demonstrated by immunoblot using polyclonal or monoclonal antiserum of M.TBH37Rv. 21 days after first vaccination of C57BL-6 mice by all three recombinant eukaryotic expressing vectors, antibody titer for Ag85B reached 1∶3200. 21 days after second vaccination, the antibody titer reached 1∶102400. The highest antibody levels induced by multivalent vaccines after the second injection were equal to or even greater than the highest antibody levels of single DNA vaccine reported in literature after third injections. Antibody titer of MPT-64 was 1∶50 after the first injection and it reached 1∶200 after the second injection. No antigen-specific antibody against ESAT-6 was detected in sera harvested from immunized mice 21 days after both injections. Antigen-specific IFN-g level of Ag85B was 110 pg/mL while no antigen-specific IFN- g level of ESAT-6 and MPT-64 was detected even after third injections. To our knowledge, it is the first time that studies of polyvalent recombinant DNA vaccines against TB were carried out in C57BL-6 mice. Our results indicated that multiple DNA vaccines could be used to enhance protective responses against M.TB.     

Minimum inductance optimal design for the gradient coil

In MRI (Magnetic Resonance Imaging), a crucial role of gradient coils is to image organism, meanwhile the inductance of the coils determines the speed of imaging. So it is of great importance to optimize designs of the gradient coils. The target field approach is an effective method to design the gradient coils. Having applied this method and performing many numerical tests, we achieved the designs of the x-、y-、z- gradient coils , with the linearity of the fields generated by the coils in a sphere of radius 0.30 m less than 5%, in which the inductance and resistance of the coils also meet the requirements.     

应用Elman神经网络的混沌时间序列预测

利用改进的 Elman神经网络对 3个典型的混沌时间序列在不同的噪声水平下进行预测 ,探讨了神经网络学习与泛化之间的关系 ,通过试凑法给出了 Elman最优的隐节点个数。并利用3种指标对预测结果进行了评估 ,结果显示 Elman网络对混沌时间序列预测的良好特性     

Isolation and purification of BVⅠ-2H from bee venom and analysis of its biological action

The medical use of bee venom for rheumatoid arthritis (RA) has a very long tradition. In this study, isolation and purification of polypeptides from bee venom were carried out on sephadex chromatography, heparin sepharose CL-6B chromatography and HPLC. Several fractions were extracted, and their effects on activation of splenocyte and THP-1 cell were studied. The inhibitory fraction was selected for further studies. Finally, BVⅠ-2H that the HPLC elution profiles was a single peak was isolated by C8 column. ESI- MS detection results showed that BVⅠ-2H was a fraction of bee venom, and the molecular weight of the major component was 644.8. BVⅠ-2H could inhibit ConA-induced splenocyte proliferation, IL-1 production and interfere with splenocyte cycle in mice. Moreover, BVⅠ-2H could inhibit PMA-induced TNFa production in THP-1 cells, which was due to its inhibitory effects on TNFa mRNA expression and protein phosphorylation of IkBa. Our studies indicated that BVⅠ-2H was one of the anti-inflammatory components of bee venom.     

基于遗传算法的模糊逻辑控制器优化设计

设计了一种新的用于模糊逻辑控制器优化的遗传算法，实现了模糊逻辑控制器参数和结构的同步快速优化。该算法对经典的简单遗传算法进行了改良，设计了一种带区间限制的十进制编码方案，实现了模糊控制器隶属度函数和控制规则的联合编码；并设计了受限分步一致交叉和变异算子，改进了经典赌轮选择法,避免了病态个体产生，加快了收敛速度。通过对典型的一阶和二阶工业对象控制器优化的仿真研究表明，相对于一般的遗传算法，该算法在群体规模较小（20或40）的情况下，能够在20代左右快速收敛到理想结果，并且在进化过程中很少产生病态个体，因此能够在小群体规模下，实现模糊控制器参数和结构的快速同步优化。     

水电工程中不锈钢材料冲蚀磨损与腐蚀的交互作用

通过水轮机目前应用较多的不锈钢材料在冲蚀磨损过程中电化学腐蚀及抗冲蚀磨损性能的研究，区分出了纯磨损、纯腐蚀、磨损对腐蚀的促进分量，及其腐蚀对磨损的促进分量等在材料失效过程中各占的比例。考察了试验材料的抗冲蚀磨损特性及其磨损与腐蚀间的交互作用，并对其失效机制进行了探索性分析。结果表明：在不同的冲蚀速度下，0Cr13Ni5Mo不锈钢的冲蚀磨损失重率小于1Cr18Ni9Ti不锈钢材料；试验材料在冲蚀磨损总失重率中，纯磨损率是占主要的；随着冲蚀速度的增加，磨损对腐蚀的促进作用也增加，同时也加强了腐蚀对磨损的促进作用。     

运用遗传算法对制冷蒸发器过热度控制的优化方法

在制冷系统动态仿真的基础上，引入遗传算法对蒸发器过热度模糊控制的隶属度函数进行了优化，并给出了三角形隶属度函数的优化方案，利用MATLAB软件实现了仿真和优化过程，进行了优化模糊控制和比例积分（PI）控制品质的对比实验。结果表明，优化后的模糊控制使过热度的超调量减小，使阀的动作平稳。     

HPLC结合APIMS/MS法研究屏边三七的皂甙成分

应用HPLC与API－MS／MS相结合，分析了屏边三七95％乙醇提取物的三萜皂甙成分，结果表明，屏边三节除含有屏边三七皂甙R1,R2，还含有少量人参皂甙Rb,Rc,Rb3和Rd。