Thermoelectric power and carrier concentration of La2−xSrxCuO4(0.03 <x <0.17) single crystals

Thermoelectric power (S) measurements have been systematically investigated in high-quality La2-x-Srx-CuO4 single crystals with different Sr concentrations (x =0.03, 0.05, 0.07, 0.1, 0.12). In this doping range studied, S remains positive, and with the increase of Sr concentration,room-temperature thermoelectric power S (290 K) decreases.An empirical formula which presents a relationship between hole concentration P and room-temperature thermoelectric power S (290 K) is reported in this note. Based on the theory of metallic diffusion model, the experimental results are discussed.     

Modeling studies on the changes of the Subtropical High over the Western Pacific during the last 100 years

Intensity index series of Subtropical High over the Western Pacific was constructed according to modeling results by using of CCM3.6 atmospheric model with climatologically SST forcing for 30 years, and with observed SST forcing from 1900 to 2000. The index series constructed by modeling closely correlated to the observations for 1951-1999 (c.c. 0.72) and to the statistically reconstructed one for 1900-1950 (c.c. 0.51). The index series for 1900-1999 showed significant 80 a and 40 a periodicity. A minimum of persistence in seasonal variations of the index occurred in Autumn, which was called "Autumn Barrier". It may relate to the "Spring Barrier", found in the seasonal variations of SST over the Eastern Equatorial Pacific. The increasing trend shown in the index series for the 20th century may associate with the global warming caused by enhancement of greenhouse effect.     

Construction of multivalent DNA vaccines forMycobacterium tuberculosis and its immunogenicity

The coding regions of Ag85B MPT-64, and ESAT-6 secreted proteins were cloned initially into the eukaryotic expression vector pJW4303, then transformed to E. coli Top 10 strain for plasmid DNA extraction and further analysis. Plasmids containing the right insertion were sequenced to confirm their identity. COS7 cells were transfected with a mixture containing serially diluted plasmid DNA encoding three secreted proteins and Lipofectin (Gibco). The supernatants and pellets prepared from various cell lines were run on SDS-PAGE gel and the expression of these proteins in COS7 cells were demonstrated by immunoblot using polyclonal or monoclonal antiserum of M.TBH37Rv. 21 days after first vaccination of C57BL-6 mice by all three recombinant eukaryotic expressing vectors, antibody titer for Ag85B reached 1∶3200. 21 days after second vaccination, the antibody titer reached 1∶102400. The highest antibody levels induced by multivalent vaccines after the second injection were equal to or even greater than the highest antibody levels of single DNA vaccine reported in literature after third injections. Antibody titer of MPT-64 was 1∶50 after the first injection and it reached 1∶200 after the second injection. No antigen-specific antibody against ESAT-6 was detected in sera harvested from immunized mice 21 days after both injections. Antigen-specific IFN-g level of Ag85B was 110 pg/mL while no antigen-specific IFN- g level of ESAT-6 and MPT-64 was detected even after third injections. To our knowledge, it is the first time that studies of polyvalent recombinant DNA vaccines against TB were carried out in C57BL-6 mice. Our results indicated that multiple DNA vaccines could be used to enhance protective responses against M.TB.     

Minimum inductance optimal design for the gradient coil

In MRI (Magnetic Resonance Imaging), a crucial role of gradient coils is to image organism, meanwhile the inductance of the coils determines the speed of imaging. So it is of great importance to optimize designs of the gradient coils. The target field approach is an effective method to design the gradient coils. Having applied this method and performing many numerical tests, we achieved the designs of the x-、y-、z- gradient coils , with the linearity of the fields generated by the coils in a sphere of radius 0.30 m less than 5%, in which the inductance and resistance of the coils also meet the requirements.     

应用Elman神经网络的混沌时间序列预测

利用改进的 Elman神经网络对 3个典型的混沌时间序列在不同的噪声水平下进行预测 ,探讨了神经网络学习与泛化之间的关系 ,通过试凑法给出了 Elman最优的隐节点个数。并利用3种指标对预测结果进行了评估 ,结果显示 Elman网络对混沌时间序列预测的良好特性     

Isolation and purification of BVⅠ-2H from bee venom and analysis of its biological action

The medical use of bee venom for rheumatoid arthritis (RA) has a very long tradition. In this study, isolation and purification of polypeptides from bee venom were carried out on sephadex chromatography, heparin sepharose CL-6B chromatography and HPLC. Several fractions were extracted, and their effects on activation of splenocyte and THP-1 cell were studied. The inhibitory fraction was selected for further studies. Finally, BVⅠ-2H that the HPLC elution profiles was a single peak was isolated by C8 column. ESI- MS detection results showed that BVⅠ-2H was a fraction of bee venom, and the molecular weight of the major component was 644.8. BVⅠ-2H could inhibit ConA-induced splenocyte proliferation, IL-1 production and interfere with splenocyte cycle in mice. Moreover, BVⅠ-2H could inhibit PMA-induced TNFa production in THP-1 cells, which was due to its inhibitory effects on TNFa mRNA expression and protein phosphorylation of IkBa. Our studies indicated that BVⅠ-2H was one of the anti-inflammatory components of bee venom.     

调制-解调技术在光纤传感式电流测量中的应用

本文把调制－解调技术应用到光纤传感式电流测量的研究中，设计了一种新型光纤大电流传感器，它具有很强的电气绝缘和抗电磁辐射干扰能力，适用于高压电网的工频大电流测量。     

关于改善缆道吊箱提升用力的研究

缆道吊箱是中小河流上测取洪水流量的测流设备，就如何减轻吊箱在使用中的提升用力，如何解决好吊箱升速大于洪水上涨速度等问题做了实质性的论述，并在实践中得到验证。收效甚好。     

基于遗传算法的模糊逻辑控制器优化设计

设计了一种新的用于模糊逻辑控制器优化的遗传算法，实现了模糊逻辑控制器参数和结构的同步快速优化。该算法对经典的简单遗传算法进行了改良，设计了一种带区间限制的十进制编码方案，实现了模糊控制器隶属度函数和控制规则的联合编码；并设计了受限分步一致交叉和变异算子，改进了经典赌轮选择法,避免了病态个体产生，加快了收敛速度。通过对典型的一阶和二阶工业对象控制器优化的仿真研究表明，相对于一般的遗传算法，该算法在群体规模较小（20或40）的情况下，能够在20代左右快速收敛到理想结果，并且在进化过程中很少产生病态个体，因此能够在小群体规模下，实现模糊控制器参数和结构的快速同步优化。     

圆柱型水槽内动/静叶相干非定常流动的实验研究

在不同的转速和动／静叶相对位置下，利用粒子图像速度场仪（PIV）对具有动／静叶的圆柱型水槽内瞬态流动非定常相干情况进行了实验研究，为了消除随机因素的干扰，实验采用锁相编码器技术和集平平均技术来处理实验数据，结果表明，圆柱型水槽内部具有较强的动／静叶相干现象，静叶区经常出现旋涡结构，通过集平均处理得到的某一转速及动／静叶相对位置情况下的速度矢量分布，可显示旋涡的位置随动叶和静叶的相对而变化，实验还发现，随着转速的升高，动／静叶相对位置对静叶区旋涡的影响变小。