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891.
公务卡实际应用问题对策研究 总被引:1,自引:0,他引:1
李昕 《济源职业技术学院学报》2011,(3):66-69
公务卡报销制度是现代信息化的标志,是电子政务化的必然结果,近几年应用过程中出现的诸多问题影响公务卡的发展。因此,针对目前公务卡应用中存在的问题进行了详细剖析,并从扩大宣传、改善用卡环境,完善公务卡银行服务体系,推动公务卡制度发展等方面提出了一些应对措施。 相似文献
892.
893.
A role for mitochondria in NLRP3 inflammasome activation 总被引:2,自引:0,他引:2
An inflammatory response initiated by the NLRP3 inflammasome is triggered by a variety of situations of host 'danger', including infection and metabolic dysregulation. Previous studies suggested that NLRP3 inflammasome activity is negatively regulated by autophagy and positively regulated by reactive oxygen species (ROS) derived from an uncharacterized organelle. Here we show that mitophagy/autophagy blockade leads to the accumulation of damaged, ROS-generating mitochondria, and this in turn activates the NLRP3 inflammasome. Resting NLRP3 localizes to endoplasmic reticulum structures, whereas on inflammasome activation both NLRP3 and its adaptor ASC redistribute to the perinuclear space where they co-localize with endoplasmic reticulum and mitochondria organelle clusters. Notably, both ROS generation and inflammasome activation are suppressed when mitochondrial activity is dysregulated by inhibition of the voltage-dependent anion channel. This indicates that NLRP3 inflammasome senses mitochondrial dysfunction and may explain the frequent association of mitochondrial damage with inflammatory diseases. 相似文献
894.
Rothberg JM Hinz W Rearick TM Schultz J Mileski W Davey M Leamon JH Johnson K Milgrew MJ Edwards M Hoon J Simons JF Marran D Myers JW Davidson JF Branting A Nobile JR Puc BP Light D Clark TA Huber M Branciforte JT Stoner IB Cawley SE Lyons M Fu Y Homer N Sedova M Miao X Reed B Sabina J Feierstein E Schorn M Alanjary M Dimalanta E Dressman D Kasinskas R Sokolsky T Fidanza JA Namsaraev E McKernan KJ Williams A Roth GT Bustillo J 《Nature》2011,475(7356):348-352
The seminal importance of DNA sequencing to the life sciences, biotechnology and medicine has driven the search for more scalable and lower-cost solutions. Here we describe a DNA sequencing technology in which scalable, low-cost semiconductor manufacturing techniques are used to make an integrated circuit able to directly perform non-optical DNA sequencing of genomes. Sequence data are obtained by directly sensing the ions produced by template-directed DNA polymerase synthesis using all-natural nucleotides on this massively parallel semiconductor-sensing device or ion chip. The ion chip contains ion-sensitive, field-effect transistor-based sensors in perfect register with 1.2 million wells, which provide confinement and allow parallel, simultaneous detection of independent sequencing reactions. Use of the most widely used technology for constructing integrated circuits, the complementary metal-oxide semiconductor (CMOS) process, allows for low-cost, large-scale production and scaling of the device to higher densities and larger array sizes. We show the performance of the system by sequencing three bacterial genomes, its robustness and scalability by producing ion chips with up to 10 times as many sensors and sequencing a human genome. 相似文献
895.
周凡 《宁夏大学学报(自然科学版)》2011,(3):275-278
从城市的商贸、服务、空间作用、制造业和对外开放5个系统,选取了10个具有代表性的评价指标,采用2006-2008年长株潭城市群的相关数据,构建城市中心性评价指标体系,并运用熵值法时长株潭城市群中8个主要城市中心性进行了综合评价,并将长株潭3城市中心性的评判结果进行了分析,从而进一步对长株潭城市群城市中心性的特征和演变过... 相似文献
896.
Skin collagen fiber-based radar absorbing materials 总被引:2,自引:0,他引:2
By using skin collagen fiber (CF) as raw material,Schiff base structure containing CF (Sa-CF) was synthesized through CF-salicylaldehyde reaction.Then a novel radar absorbing material (Fe-Sa-CF) was prepared by chelating reaction between Sa-CF and Fe 3+.The coaxial transmission and reflection method was used to analyze the complex permittivity and complex magnetic permeability of these CF-based materials,and the radar cross section (RCS) method was used to investigate their radar absorbing properties in the frequency range of 1.0-18.0 GHz.Experimental results indicated that the conductivity of CF increased from initial 1.08×10-11 to 2.86×10-6 S/cm after being transferred into Fe-Sa-CF,and its dielectric loss tangent (tanδ) in the frequency range of 1.0-17.0 GHz also increased.These facts suggest that the Fe-Sa-CF is electric-loss type radar absorbing material.In the frequency range of 3.0-18.0 GHz,Sa-CF (1.0 mm in thickness) exhibited somewhat radar absorbing property with maximum radar reflection loss (RL) of-4.73 dB.As for Fe-Sa-CF,the absorbing bandwidth was broadened,and the absorbing intensity significantly increased in the frequency range of 1.0-18.0 GHz where a maximum radar RL of-9.23 dB was observed.In addition,the radar absorbing intensity of Fe-Sa-CF can be further improved by increasing membrane thickness.When the thickness reached to 2.0 mm,the RL values of Fe-Sa-CF were-15.0-18.0 dB in the frequency range of 7.0-18.0 GHz.Consequently,a kind of novel radar absorbing material can be prepared by chemical modification of collagen fiber,which is characterized by thin thickness,low density,broad absorption bandwidth and high absorption intensity. 相似文献
897.
Sea surface temperature east of Australia: A predictor of tropical cyclone frequency over the western North Pacific? 总被引:7,自引:1,他引:6
The relationship between sea surface temperature (SST) east of Australia and tropical cyclone frequency over the western North Pacific (WNPTCF) is analyzed by use of observation data.The WNPTCF from June to October is correlated negatively to spring SST east of Australia.When the spring SST is in the positive phase,a cyclonic circulation anomaly in the upper troposphere and an anticyclonic circulation anomaly in the lower troposphere prevail over the western North Pacific from June to October,concurrent with an anomalous atmospheric subsidence and an enlarged vertical zonal wind shear.These conditions are unfavorable for tropical cyclone genesis,and thus WNPTCF decreases.The negative phase of the spring SST east of Australia leads to more tropical cyclones over the western North Pacific.The spring SST east of Australia may give rise to simultaneous change in tropical atmospheric circulation via the teleconnection wave train,and then subsequently affect atmospheric circulation variation over the western North Pacific. 相似文献
898.
Feng Wang DongMin Zhang YanFen Ding LiXin Zhang MingShu Yang BaoLiang Jiang ShiMin Zhang MuYang Ai GuangWen Liu ShuJie Zhi LianFeng Huo Xin Ouyang Li Li 《科学通报(英文版)》2011,56(1):14-17
The pipeline transportation of waxy crude oil is a problem both at home and abroad.In this paper,a novel nanohybrid pour-point depressant (PPD) was used to decrease the pour point and viscosity of waxy crude oil.The pour point and apparent viscosity of waxy crude oil was decreased significantly upon addition of the nanohybrid PPD,and the long-term stability of the nanohybrid PPD was superior to that of a conventional ethylene-vinyl acetate copolymer PPD.Polarized optical microscopy and X-ray diffraction were used to study the effect of the nanohybrid PPD on the crystallization of crude oil.Addition of the nanohybrid PPD reduced the amount of wax crystals,prevented their aggregation,and reduced the temperature at which the crude oil started to crystallize.The significant effect of this nanohybrid PPD on the pour point and viscosity depressing of crude oil is of great importance for facilitating the safe,efficient and energy-minimized transportation of waxy crude oil. 相似文献
899.
针对在无人值守的情况下,如何将网络突发故障及时通知给网络管理人员以便快速响应的问题,提出了基于Cacti与飞信的网络实时故障报警平台.利用Cacti的SNMP信息轮询机制,实时获取当前网络中的设备故障与恢复信息,通过发送飞信的方式将故障信息传递到网络管理人员的手机终端.运行结果表明,网络管理人员排除故障时间大大缩短,管... 相似文献
900.
为了定量评估城市绿地吸收CO2改善城市生态环境的效果,2006年4月—2007年3月在北京海淀公园绿地使用涡度相关系统连续观测CO2通量、总辐射、大气温度,并使用冠层分析仪测量叶面积指数,研究CO2通量的变化及其影响因素.结果表明,绿地CO2通量受植被生物活动的影响呈现明显的季节变化特征,晴天天气状况下CO2通量日均值FCO2在4—10月为负值,绿地是CO2汇,在6—9月是CO2强吸收汇,FCO2约-0.100—-0.120mg/m2.s,而在11—3月FCO2为正值,绿地为CO2源,12—2月是CO2强排放源,FCO2约0.100mg/m2.s.绿地CO2通量受总辐射、LAI、大气温度的显著影响,净辐射的影响明显大于大气温度,净辐射越大、LAI越大、大气温度越高,绿地光合作用吸收CO2的能力越强.观测期间一年海淀公园绿地CO2的净吸收量约为615gCO2/m2. 相似文献