MSTP在镇江电力通信传输网的应用

文章介绍了基于SDH的多业务传送设备MSTP的概念特点及关键技术,分析了MSTP在镇江电力通信传输网以太网业务的应用。     

In vivo genome editing restores haemostasis in a mouse model of haemophilia

Editing of the human genome to correct disease-causing mutations is a promising approach for the treatment of genetic disorders. Genome editing improves on simple gene-replacement strategies by effecting in situ correction of a mutant gene, thus restoring normal gene function under the control of endogenous regulatory elements and reducing risks associated with random insertion into the genome. Gene-specific targeting has historically been limited to mouse embryonic stem cells. The development of zinc finger nucleases (ZFNs) has permitted efficient genome editing in transformed and primary cells that were previously thought to be intractable to such genetic manipulation. In vitro, ZFNs have been shown to promote efficient genome editing via homology-directed repair by inducing a site-specific double-strand break (DSB) at a target locus, but it is unclear whether ZFNs can induce DSBs and stimulate genome editing at a clinically meaningful level in vivo. Here we show that ZFNs are able to induce DSBs efficiently when delivered directly to mouse liver and that, when co-delivered with an appropriately designed gene-targeting vector, they can stimulate gene replacement through both homology-directed and homology-independent targeted gene insertion at the ZFN-specified locus. The level of gene targeting achieved was sufficient to correct the prolonged clotting times in a mouse model of haemophilia B, and remained persistent after induced liver regeneration. Thus, ZFN-driven gene correction can be achieved in vivo, raising the possibility of genome editing as a viable strategy for the treatment of genetic disease.     

完全支持数据更新的XML压缩编码

为了有效地更新和查询XML数据,提出了一种新的XML编码方案-分数路径编码(简写为FAPE).FAPE充分利用在两个分数间可以插入无穷多个分数这一特点,支持XML结点数据的无限更新,同时FAPE将结点的相关信息保存在相应的表中,避免记录重复的信息.实验表明:FAPE节省了存储空间,提高了查询效率,更新所花的时间更少.     

可约矩阵特征值的扰动

主要研究可约矩阵特征值的扰动.对于可约矩阵,给出了Bauer-Fike型的一些结果,这些结果推广了文献[3-5]中相应的结果.     

基于熵值法的长株潭城市中心性研究

从城市的商贸、服务、空间作用、制造业和对外开放5个系统,选取了10个具有代表性的评价指标,采用2006-2008年长株潭城市群的相关数据,构建城市中心性评价指标体系,并运用熵值法时长株潭城市群中8个主要城市中心性进行了综合评价,并将长株潭3城市中心性的评判结果进行了分析,从而进一步对长株潭城市群城市中心性的特征和演变过...     

Sea surface temperature east of Australia： A predictor of tropical cyclone frequency over the western North Pacific？

The relationship between sea surface temperature (SST) east of Australia and tropical cyclone frequency over the western North Pacific (WNPTCF) is analyzed by use of observation data.The WNPTCF from June to October is correlated negatively to spring SST east of Australia.When the spring SST is in the positive phase,a cyclonic circulation anomaly in the upper troposphere and an anticyclonic circulation anomaly in the lower troposphere prevail over the western North Pacific from June to October,concurrent with an anomalous atmospheric subsidence and an enlarged vertical zonal wind shear.These conditions are unfavorable for tropical cyclone genesis,and thus WNPTCF decreases.The negative phase of the spring SST east of Australia leads to more tropical cyclones over the western North Pacific.The spring SST east of Australia may give rise to simultaneous change in tropical atmospheric circulation via the teleconnection wave train,and then subsequently affect atmospheric circulation variation over the western North Pacific.     

一种基于标记点的近景摄影测量系统

给出了一种基于标记点的鲁棒三维重建摄影测量系统;采用编码点和非编码点等标记点方式.为了减少不同图像间误匹配的概率,采用一种新的基于编码点的匹配方法,不同图像间非编码点的匹配从编码点开始,并通过相似性准则、模糊度准则和距离误差准则来剔除误匹配,可获得非常高的正确匹配率.采用一种新的基于标记点的加权迭代特征算法,用编码点恢复相机的投影矩阵,从而可以确定相机的外部姿态参数;用非编码点恢复3D坐标.与已有的加权迭代特征算法比较,该算法避免了所有点参与计算相机的投影矩阵,运算速度更快.由于采用标记点的亚像素定位方法,提高了3D重建精度.实验结果表明,在3D重建方面,该系统是强壮和精确的.     

多相移光纤光栅光谱特性分析

为了研究多相移光纤光栅的光谱特性,探究其在光纤通信和光纤传感领域的应用,利用传输矩阵法,通过Matlab编程对多相移光纤光栅中等分相移光栅、相移级联光栅及混合相移光栅在不同相移个数、不同相移量大小、不同位置放置时的传输光谱特性进行了仿真和研究.结论表明:等分相移光栅可以通过增加相移个数来实现多波长的激光输出,相移量不同激光波长的输出也不同.相移级联光栅可用作带宽滤波器,通过增加相移光栅的级联数增加带宽.     

全行驶状态下虚拟轨道列车的动载及道路友好特性

为分析虚拟轨道列车在站间全行驶状态下（牵引、匀速、制动）的动载特性和道路友好性,基于车辆动力学、轮胎动力学、非线性动力学等理论,构建了随机路面激励下的虚拟轨道列车动力学模型,该模型考虑了车辆之间的耦合作用和轮胎-路面的相互作用,并对该动力学模型进行了验证。通过理论分析和数值计算,对虚拟轨道列车在站间全行驶状态下的动载特性和道路友好性进行了探究,同时分析了运行速度、路面等级和加/减速度的影响。结果表明：全行驶状态下的各轮纵向力趋于稳定值,牵引和制动状态下大小相等,方向相反,匀速状态下趋于零。牵引状态下车辆1前轴垂向动载荷均方根值最大,而制动状态下车辆3后轴最大。相较于牵引和制动状态,匀速状态下的道路友好性更优。垂向动载荷均方根值和道路友好性均与运行速度、加/减速度均呈正相关,与路面等级呈负相关。研究内容能够为虚拟轨道列车的运行模式提供建议以提高运行效率,同时,能够为沥青路面的选型提供指导以减缓道路损坏。