翼身融合航行体操纵特性研究

翼身融合航行体以其独特的外形特征和机动性能成为未来海洋发展的重要方向,而人们对这一类型的航行体操纵特点并不了解.本文采用基于半相对坐标系的数值模拟方法对新型航行体操纵特性进行研究,并且通过量纲分析对主要影响参数进行分析.发现水平面回转时给定航速条件下,航行体尾部漩涡会随着旋转半径的变化出现偏转现象,进一步的数值模拟结果表明:旋转半径越小,左右漩涡的不对称性会越明显.当旋转半径给定时,不同航速条件下,航行体尾涡的左右分离位置基本一致.对比发现该类航行体的垂直面回转操纵性要优于水平面回转操纵性,即这类航行体在改变航行深度机动方面具有更大优势.     

数据和知识融合驱动的智能过程系统工程研究进展

智能过程系统工程教育部工程研究中心建设十余年来,开展了一系列卓有成效的基于数据和知识融合驱动的智能化过程系统工程（PSE）科学研究、技术创新和工程应用。本文重点介绍过程工业节能减排降耗和安全运行相关的关键技术——建模与优化、报警管理与故障诊断以及能效分析与评价三大应用的研究进展,最后结合大数据、云计算、工业4.0、智能制造、人工智能等技术展望了PSE的未来发展方向。     

部分线性面板数据模型中个体效应的Bootstrap Hausman检验

对于面板数据模型而言,为了提高估计和预报的精度,区分个体固定效应和个体随机效应非常重要。 针对部分线性面板数据模型,在小样本下采用参数 Hausman 检验方法来识别模型中的个体效应,并通过 Bootstrap 抽样方法求得统计量的上分位点进而构造假设检验的拒绝域。 模拟结果显示,此检验的稳健性和可靠性比现有的非参数检验高,且在计算量和计算时间上有较大优势。     

变系数部分线性EV面板数据模型的效应检验

研究了带测量误差的变系数部分线性面板数据模型中个体效应的检验问题。 基于截面最小二乘方法分别对固定效应模型和随机效应模型中参数部分和非参数部分进行估计,经过纠偏处理后分别得到修正后的估计量,并构造出参数 Hausman 检验统计量和非参 Hausman 检验统计量;进一步,在小样本下结合 Bootstrap 抽样方法和Hausman 检验统计量得到检验的拒绝域,并通过模拟来检验统计量的功效;最后利用本文方法实证分析研究了国内 16 家上市银行绩效影响因素,并给出了实质性建议。     

Specific anti-tumor effect induced by attenuated <Emphasis Type="Italic">Salmonella typhimurium</Emphasis> vaccine expressing extracellular region of vascular endothelial growth factor receptor 2

The purposes of this research were to study the stable expression of exogenous gene encoding therapeutic protein in attenuated Salmonella typhimurium, observe the metabolism of oral gene vaccine carried by attenuated Salmonella typhimurium in BALB/c mouse, and investigate the feasibility of prevention and treatment of tumors by the recombinant bacteria. Recombinant plasmid pcDNA3.1＋ VEGFR2（n1-7） was transformed into competent attenuated Salmonella typhimuriurn SL3261 to develop oral DNA vaccine SL3261-pcDNA3.1＋VEGFR2（n1-7）. To observe whether the exogenous gene can be expressed in the recombinant bacteria, PCR was performed to amplify the CMV promoter of the eukaryotic expression vector as the proof of stable expression of exogenous protein; transmission elec- tron microscopy （TEM） was applied to observe the morphology of the recombinant bacteria to confirm that the exogenous gene has no impact on the growth of the bacteria, and then BALB/c mice were immunized with the gene vaccine. After inoculation of the gene vaccine, the recombinant bacteria SL3261 could be detected in the tissues such as small intestine, colon, liver and spleen. And then, mice in each group were challenged with tumor cells. The results of animal experiment showed that tumor growth of the mice in experimental group was inhibited and survival time of immunized mice was prolonged compared with control groups. A higher lymphocyte infiltration in tumors from animals treated with DNA vaccine was observed. Immunohistochemical analysis of tumor samples revealed an enhanced accumulation of CD8^＋ cytotoxic T lymphocytes, as well as an increase in CD4^＋ cells in the tumore of animals treated with the oral gene vaccine compared to tumors from control group mice. UI- trestructure of the tumor tissue showed that tumor cells in the samples of the immunized mice were well-differentiated. Our research confirmed that the exogenous gene can be stably expressed in the attenuated Salmonella typhimurium and has no impact on the growth of the r     

基于分位数回归的企业债信用风险研究

将非参数GARCH模型的方差方程取对数变换后所得的模型用于估计企业债利差波动率。针对模型误差的非对称性，利用更为稳健的分位数回归方法估计改进后的非参数可加GARCH模型。实证分析结果表明，改进后的模型对波动率的估计更为有效；分位数回归方法比最小二乘回归方法能更有效的克服模型误差的非正态影响，对异常值的敏感程度更低，是一种非常稳健的估计方法。     

A bio-inspired approach for cognitive radio networks

The recent increasing interest in cognitive radio networks has motivated the study and development of new approaches capable of coping with the intrinsic challenges of this kind of network, such as dynamic spectrum availability, distributed and heterogeneous network architectures, and soaring complexity. The bio-inspired approaches, with appealing characteristics such as autonomy, adaptation and collective intelligence of collaborative individuals, have been extensively studied. This paper presents a comprehensive survey of bio-inspired approaches for cognitive radio networks, emphasizing their domains of application. Specifically, ant colony optimization and particle warm optimization are further investigated with examples and numerical simulation.     

变系数固定效应面板数据模型的估计

在面板数据下基于变系数固定效应模型，采用两步估计方法和截面核估计方法来估计模型中的变系数部分及固定效应。模拟结果表明，当样本数据较小且观测次数较多时，两步估计法的估计效率略高于截面核估计的；而当样本数据较大且观测次数较少时，截面核估计方法的估计效率比两步估计的略好。本文通过两组不同样本的模拟数据验证了两种估计方法的有效性，说明变系数固定效应模型是处理面板数据的有效工具。     

基于神经网络和粒子群算法的遗传位点与患病信息的关联性分析

基于遗传疾病与某些遗传基因位点存在的较强关联性，并考虑到位点间存在交互作用的情形，提出了关联性最强的位点组合的筛选方法。将每个候选位点组合对应的基于神经网络的预报准确率作为评价标准，用粒子群算法（PSO）通过迭代逼近找出最优的位点组合，并与神经网络权重分析法进行比较。结果表明，由本文方法得到的位点组合预报精度更高，对患病情况有着较好的识别效果，可为遗传疾病诊断等提供参考方法。     

Coupling of thermocapillary convection and evaporation effect in a liquid layer when the evaporating interface is open to air

The coupling mechanism of thermocapillary convection and evaporation effect in evaporating liquids was studied experimentally. The experiments were carried out to study a thin evaporating liquid layer in a rectangular test cell when the upper surface was open to air. By altering the imposed horizontal temperature differences and heights of liquid layers, the average evaporating rate and interfacial temperature profiles were measured. The flow fields were also visualized by PIV method. For comparison, the ex...