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841.
Xiuli Liu 《系统科学与复杂性》2018,31(6):1554-1570
The paper established a double filtering method (DFM) to visualize the skeleton industrial structure (SIS) of one economy and find its evolution rule. Different with the previous researches, this method is from a new view of industrial conjunctions combined by leading sectors to depict the industrial structure. It was proved that the leading sector selected by DFM must be key sector selected by Hirschman-Rasmussen method. Applied DFM to input-output tables of China, Japan and USA and MFA to Japan and USA, the results analysis showed that DFM could overtake the two main shortcomings of minimum flow analysis (MFA), scratch SIS of each economy with its own characteristics, visualize the general evolution rules of the industrial structure with crisscrossed conjunctions among leading sectors. 相似文献
842.
Progress in research on endocannabinoid signaling has greatly advanced our understanding of how it controls neural circuit excitability in health and disease. In general, endocannabinoid signaling at excitatory synapses suppresses seizures by inhibiting glutamate release. In contrast, endocannabinoid signaling promotes seizures by inhibiting GABA release at inhibitory synapses. The physiological distribution of endocannabinoid signaling molecules becomes disrupted with the development of epileptic focus in patients with mesial temporal lobe epilepsy and in animal models of experimentally induced epilepsy. Augmentation of endocannabinoid signaling can promote the development of epileptic focus at initial stages. However, at later stages, increased endocannabinoid signaling delays it and suppresses spontaneous seizures. Thus, the regulation of endocannabinoid signaling at specific synapses that cause hyperexcitability during particular stages of disease development may be effective for treating epilepsy and epileptogenesis. 相似文献
843.
Quantitative analysis has always been a difficult problem in security analysis of intrusion tolerance systems. An intrusion tolerance model based on multiple recovery mechanisms is introduced in this paper and how to quantify the security attributes of the model is proposed. A state transition model with recovery states more accurately describes the dynamic behavior of the system. Considering that recovery mechanisms have a great impact on the security performance of the system, we set up the cost models corresponding to different recovery mechanisms. We propose a feasible security measure based on mean cost to security failure in order to evaluate the system cost during the recovery phase. The experimental results confirmed the feasibility of the proposed methods. 相似文献
844.
In this paper, a life-cycle model with retirement is set up to study how an individual chooses the optimal retiring age on account of wage growth rate, longevity and healthy state. It is proved that there exists optimal retiring age under given conditions. The numerical simulations are given to show how wage growth rate, longevity and healthy state affect retiring age. 相似文献
845.
Naomi Joy Godden 《Systemic Practice and Action Research》2018,31(1):55-73
Co-operative inquiry is an under-explored method in community-based research. Its democratic approach involves a group of “co-researchers” collaboratively inquiring into a mutually-agreed research topic through systematic cycles of reflection and action. This article shares the process, outcomes, and methodological reflections of three co-operative inquiries that were conducted as part of an international study regarding love in community work. Groups of up to 10 community workers in rural villages in Timor-Leste, Australia, and Peru engaged in co-operative inquiry to collaboratively develop new knowledge to inform practice. The article analyses data regarding co-inquirer experiences of the methodology, and identifies the strengths and challenges of the co-operative inquiry method to support the collective generation of new knowledge. The article concludes that co-operative inquiry involves shared power, participation, action, and contextual reflexivity, and is a useful method for community workers to collaboratively develop innovative approaches to community work practice through cycles of reflection and action. 相似文献
846.
Data fitting is an extensively employed modeling tool in geometric design. With the advent of the big data era, the data sets to be fitted are made larger and larger, leading to more and more leastsquares fitting systems with singular coefficient matrices. LSPIA (least-squares progressive iterative approximation) is an efficient iterative method for the least-squares fitting. However, the convergence of LSPIA for the singular least-squares fitting systems remains as an open problem. In this paper, the authors showed that LSPIA for the singular least-squares fitting systems is convergent. Moreover, in a special case, LSPIA converges to the Moore-Penrose (M-P) pseudo-inverse solution to the leastsquares fitting result of the data set. This property makes LSPIA, an iterative method with clear geometric meanings, robust in geometric modeling applications. In addition, the authors discussed some implementation detail of LSPIA, and presented an example to validate the convergence of LSPIA for the singular least-squares fitting systems. 相似文献
847.
End-use energy consumption can reflect the industrial development of a country and the living standards of its residents. The study of end-use energy consumption can provide a solid basis for industrial restructuring, energy saving, and emission reduction. In this paper, we analyzed the end-use energy consumption of a region in Northwestern China, and applied the Markov prediction method to forecast the future demand of different types of end-use energy. This provides a reference for the energy structure optimization in the Northwestern China. 相似文献
848.
849.
Lígia O. Martins Paulo Durão Vânia Brissos Peter F. Lindley 《Cellular and molecular life sciences : CMLS》2015,72(5):911-922
The ubiquitous members of the multicopper oxidase family of enzymes oxidize a range of aromatic substrates such as polyphenols, methoxy-substituted phenols, amines and inorganic compounds, concomitantly with the reduction of molecular dioxygen to water. This family of enzymes can be broadly divided into two functional classes: metalloxidases and laccases. Several prokaryotic metalloxidases have been described in the last decade showing a robust activity towards metals, such as Cu(I), Fe(II) or Mn(II) and have been implicated in the metal metabolism of the corresponding microorganisms. Many laccases, with a superior efficiency for oxidation of organic compounds when compared with metals, have also been identified and characterized from prokaryotes, playing roles that more closely conform to those of intermediary metabolism. This review aims to present an update of current knowledge on prokaryotic multicopper oxidases, with a special emphasis on laccases, anticipating their enormous potential for industrial and environmental applications. 相似文献
850.
Multicellular organisms contain numerous symbiotic microorganisms, collectively called microbiomes. Recently, microbiomic research has shown that these microorganisms are responsible for the proper functioning of many of the systems (digestive, immune, nervous, etc.) of multicellular organisms. This has inclined some scholars to argue that it is about time to reconceptualise the organism and to develop a concept that would place the greatest emphasis on the vital role of microorganisms in the life of plants and animals. We believe that, unfortunately, there is a problem with this suggestion, since there is no such thing as a universal concept of the organism which could constitute a basis for all biological sciences. Rather, the opposite is true: numerous alternative definitions exist. Therefore, comprehending how microbiomics is changing our understanding of organisms may be a very complex matter. In this paper we will demonstrate that this pluralism proves that claims about a change in our understanding of organisms can be treated as both true and untrue. Mainly, we assert that the existing concepts differ substantially, and that only some of them have to be reconsidered in order to incorporate the discoveries of microbiomics, while others are already flexible enough to do so. Taking into account the plurality of conceptualisations within different branches of modern biology, we will conduct our discussion using the developmental and the cooperation–conflict concepts of the organism. Then we will explain our results by referring to the recent philosophical debate on the nature of the concept of the organism within biology. 相似文献