变系数对流扩散方程的交替分段显-隐式方法

应用交替分段显－隐方法求解变系数对流扩散方程，此方法具有很好的并行性且无条件稳定。     

数字调制方式的识别研究

数字调制方式的识别对于通信信号分析有着重要的作用 .此文首先介绍了数字调制方式的识别算法(DMRA) ,即判决理论算法的原理 ;然后提出了一种基于该算法的判决流程 ;最后在软件环境中进行计算机仿真 ,通过实验数据对该算法进行修正 .仿真结果表明 ,该修正算法具有较高的识别率和良好的可行性 .     

Science Letters： A synthetic Toll-like receptor 2 ligand decreases allergic immune responses in a mouse rhinitis model sensitized to mite allergen

It has been proposed that activation of Toll-like receptors （TLRs） plays crucial roles in the polarization of adaptive immune responses. A synthetic Toll-like receptor 2 （TLR2） ligand, Pam3CSK4, has been reported to modulate the balance of Th1/Th2 responses. We evaluated the modulation effect of Pam3CSK4 on allergic immune response in a mouse rhinitis model sensitized to house dust mite allergen （HDM）. Mice were sensitized and challenged with Dermatophagoidesfarinae allergen （Der f）, and then the allergic mice were treated by Pam3CSK4. Nasal allergic symptoms and eosinophils were scored. Der f-specific cytokine responses were examined in the splenocytes and bronchoalveolar lavage fluid （BALF）. Serum level of total IgE was also detected. After establishing a mouse allergic rhinitis model with HDM, we have showed that Pam3CSK4 treatment not only ameliorated the nasal allergic symptoms remarkably but also decreased the eosinophils and total inflammation cells in BALF significantly. Analysis of cytokine profile found that IFN-7 released from either BALF or stimulated splenocytes increased markedly in Pam3CSK4-treated mice, while IL-13 decreased significantly. Moreover, serum level of total IgE was significantly lower in Pam3CSK4-treated mice than in the untreated. Thus, in an allergic rhinitis mouse model developed with HDM, Pam3CSK4 was shown to exhibit an antiallergic effect, indicating its potential application in allergic diseases.     

山西省代县碾子沟金红石矿的成因分析

金红石在基性岩中是由于自变质作用和后期热液作用的结果,使矿体中金红石加富,该区矿床属岩浆矿床。介绍了代县碾子沟矿区金红石矿产的地质特征,就代县碾子沟矿区金红石矿的成矿原因进行了分析。     

漳州某基坑抽水引起地面沉降的初探

由于基坑快速抽水导致基坑周边地面沉降。通过对场地因抽水引起地面沉降的计算和试抽水等方面的前期工作,分析了因基坑降水对地面沉降的影响,并据此来调整完善基坑降水方案,取得了明显的社会和经济效益。     

求解Po-函数非线性互补问题的一个下降牛顿算法

构建了一个新的光滑价值函数来求解Po-函数非线性互补问题.区别于以往所构建的价值函数,构建的新的光滑价值函数不含任何光滑参数.对于Po-函数,可以得到,此价值函数的任一稳定点都是非线性互补问题的解.基于这个简单的光滑价值函数,提出了求解Po-函数非线性互补问题的一个下降牛顿算法.在适当的条件下,该算法的全局收敛性及局部超线性(二次收敛性)也得到了证明.     

Finding finer functions for partially characterized proteins by protein-protein interaction networks

Based on high-throughput data, numerous algorithms have been designed to find functions of novel proteins. However, the effectiveness of such algorithms is currently limited by some fundamental factors, including (1) the low a-priori probability of novel proteins participating in a detailed function; (2) the huge false data present in high-throughput datasets; (3) the incomplete data coverage of functional classes; (4) the abundant but heterogeneous negative samples for training the algorithms; and (5) the lack of detailed functional knowledge for training algorithms. Here, for partially characterized proteins, we suggest an approach to finding their finer functions based on protein interaction sub-networks or gene expression patterns, defined in function-specific subspaces. The proposed approach can lessen the above-mentioned problems by properly defining the prediction range and functionally filtering the noisy data, and thus can efficiently find proteins’ novel functions. For thousands of yeast and human proteins partially characterized, it is able to reliably find their finer functions (e.g., the translational functions) with more than 90% precision. The predicted finer functions are highly valuable both for guiding the follow-up wet-lab validation and for providing the necessary data for training algorithms to learn other proteins.     

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases.

Astacin, a digestive zinc-endopeptidase from the crayfish Astacus astacus L., is the prototype for the 'astacin family', which includes mammalian metallo-endopeptidases and developmentally regulated proteins of man, fruitfly, frog and sea urchin. Here we report the X-ray crystal structure of astacin, which reveals a deep active-site cleft, with the zinc at its bottom ligated by three histidines, a water molecule and a more remote tyrosine. The third histidine (His 102) forms part of a consensus sequence, shared not only by the members of the astacin family, but also by otherwise sequentially unrelated proteinases, such as vertebrate collagenases. It may therefore represent the elusive 'third' zinc ligand in these enzymes. The amino terminus of astacin is buried forming an internal salt-bridge with Glu 103, adjacent to His 102. Astacin pro-forms extended at the N terminus, as observed for some 'latent' mammalian astacin homologues, did not exhibit this 'active' conformation, indicating an activation mechanism reminiscent of trypsin-like serine proteinases.     

弧焊机器人控制系统

本文介绍一种二级计算机控制的弧焊机器人控制系统。在考虑相邻关节影响的条件下，对弧焊机器人控制系统的硬件电路和控制方法进行了分析和设计．     

中药材中孳生粉螨的初步调查

本文采用清水漂浮法和塔氏电热集螨器分离法,共分离中药材样本124种,1240份,从中分离出粉螨45种,隶属7科23属.得出结论:中药材粉螨的污染严重,应加强对中药螨类的防治,以保护中药材及预防人体螨病.