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1.
轻型钢木混合楼盖水平荷载转移性能 总被引:1,自引:0,他引:1
通过水平集中荷载作用下一层两跨的钢木混合结构拟静力试验,研究轻型钢木混合楼盖弹性状态下平面内刚度及其对水平荷载的分配.为了量化楼盖平面内刚度对水平荷载分配的影响,定义了楼盖水平荷载转移能力系数β,探讨了楼盖平面内刚度与竖向抗侧力构件抗侧刚度比值α与β的关系,并根据α及β数值大小定义刚性楼盖.试验结果表明,轻型钢木混合楼盖在仅铺设SPF(云杉-松木-冷杉)规格材面板且竖向抗侧力构件仅为钢框架时,α在0.5~1.0之间,β为64.0%左右,楼盖已能较好地分配水平荷载;铺设水泥砂浆面层后,α增至3.0以上,β增至90.0%左右,结构有很强的空间协同作用,楼盖为刚性楼盖;当竖向钢框架间加上轻型木剪力墙后,α下降至1.0~2.0之间,β下降至78.0%左右,楼盖不再为刚性. 相似文献
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无线AdHo网络是现阶段运用较广的一种对等式网络,具有良好自治性、快速组网和无基础设施的特点,可通过多个节点转发和无线信道实现数据间的传送。为更好地避免节点间能量的浪费,以AODV路由协议的节点思想为基础,根据各个节点剩余能量划分三类节点,以便选择出符合实际需求的、更优的传输路径,达到节省网络能耗、均衡节点能耗和提高带宽资源的目的。 相似文献
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Yingxin Yu Zenghua Qi Shengtao Ma Lin Xu Jing Zheng Yanpeng Gao Xiantao Shen Yaqi Cai Weiping Zhang Guiying Li Taicheng An 《科学通报(英文版)》2021,(17):1705-1708
Rapid economic development and industrialization have left many risk sites around the world with significant or potential soil contamination due to industrial p... 相似文献
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Taxonomy of a tetrigid genus Saussurella Bolivar is reviewed. One new species, Saussurella brachycornis sp. nov. is described from China and an updated identification key to all known species of the genus is given, as well as brief comments on phylogenetic relationships and distributions of the genus. 相似文献
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Jing Qu Shuqing Yu Yuan Zheng Yan Zheng Hui Yang Jianliang Zhang 《Cellular and molecular life sciences : CMLS》2017,74(4):683-695
Aptamers are small single-stranded DNA or RNA oligonucleotide fragments or small peptides, which can bind to targets by high affinity and specificity. Because aptamers are specific, non-immunogenic and non-toxic, they are ideal materials for clinical applications. Neurodegenerative disorders are ravaging the lives of patients. Even though the mechanism of these diseases is still elusive, they are mainly characterized by the accumulation of misfolded proteins in the central nervous system. So it is essential to develop potential measures to slow down or prevent the onset of these diseases. With the advancements of the technologies, aptamers have opened up new areas in this research field. Aptamers could bind with these related target proteins to interrupt their accumulation, subsequently blocking or preventing the process of neurodegenerative diseases. This review presents recent advances in the aptamer generation and its merits and limitations, with emphasis on its applications in neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, transmissible spongiform encephalopathy, Huntington’s disease and multiple sclerosis. 相似文献
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Danielle Kamato Muhamad Ashraf Rostam Rebekah Bernard Terrence J. Piva Nitin Mantri Daniel Guidone Wenhua Zheng Narin Osman Peter J. Little 《Cellular and molecular life sciences : CMLS》2015,72(4):799-808
G protein-coupled receptor (GPCR) signalling is mediated through transactivation-independent signalling pathways or the transactivation of protein tyrosine kinase receptors and the recently reported activation of the serine/threonine kinase receptors, most notably the transforming growth factor-β receptor family. Since the original observation of GPCR transactivation of protein tyrosine kinase receptors, there has been considerable work on the mechanism of transactivation and several pathways are prominent. These pathways include the “triple membrane bypass” pathway and the generation of reactive oxygen species. The recent recognition of GPCR transactivation of serine/threonine kinase receptors enormously broadens the GPCR signalling paradigm. It may be predicted that the transactivation of serine/threonine kinase receptors would have mechanistic similarities with transactivation of tyrosine kinase pathways; however, initial studies suggest that these two transactivation pathways are mechanistically distinct. Important questions are the relative importance of tyrosine and serine/threonine transactivation pathways, the contribution of transactivation to overall GPCR signalling, mechanisms of transactivation and the range of cell types in which this phenomenon occurs. The ultimate significance of transactivation-dependent signalling remains to be defined but it appears to be prominent and if so will represent a new cell signalling frontier. 相似文献
10.
Resistive Random Access Memory(ReRAM)-based neural network accelerators have potential to surpass their digital counterparts in computational efficiency and performance. However, design of these accelerators faces a number of challenges including imperfections of the Re RAM device and a large amount of calculations required to accurately simulate the former. We present XB-SIM, a simulation framework for Re RAM-crossbar-based Convolutional Neural Network(CNN) accelerators. XB-SIM can be flexibly configured to simulate the accelerator's structure and clock-driven behaviors at the architecture level. This framework also includes an Re RAM-aware Neural Network(NN) training algorithm and a CNN-oriented mapper to train an NN and map it onto the simulated design efficiently. Behavior of the simulator has been verified by the corresponding circuit simulation of a real chip. Furthermore, a batch processing mode of the massive calculations that are required to mimic the behavior of Re RAM-crossbar circuits is proposed to fully apply the computational concurrency of the mapping strategy. On CPU/GPGPU, this batch processing mode can improve the simulation speed by up to 5.02 or 34.29. Within this framework, comprehensive architectural exploration and end-to-end evaluation have been achieved, which provide some insights for systemic optimization. 相似文献