相转移催化剂在合成苯乙哌啶中间体中的应用

用相转移催化剂的方法合成革乙哌啶的中间体,对原生产工艺进行了改进,摸索出中间体合成的最佳条件和最高收率,使改进前后的合成收率由34.6%提高到72.4%。     

用核磁共振量子计算机研究量子退相干问题

量子退相干理象是由系统与环境的纠缠所引起的系统相干性的消失，是一种纯粹量子力学效应[1].     

A Framework to Support Agility Strategy Formulation

In the last decade, turbulent times and uncertainti es in the business environment have made ground for a new business era, and “chang e“ has become a major characteristic of the new era. This has resulted in tirele ss evolution of business systems and the creation of new manufacturing and manag ement philosophies. Agile Manufacturing (AM) is a step forward in generation of new means for better performance and success of business, and in practice is a s trategic approach to manufacturing by considering ...     

非公有制经济参与西部大开发若干问题的研究

我国经济发展机制的重要变化是非公有制经济迅速成长壮大,并以其特有的活力与生机成为经济发展的新的增长空间。注重和加强非公有制经济参与西部大开发的问题研究,对促进以国有经济为主导的西部地区经济高速发展,具有重要的理论意义和实际意义,并能为政府关于区域和西部开发的发展战略提供参考依据。     

A calcium sensor in the sodium channel modulates cardiac excitability.

Sodium channels are principal molecular determinants responsible for myocardial conduction and maintenance of the cardiac rhythm. Calcium ions (Ca2+) have a fundamental role in the coupling of cardiac myocyte excitation and contraction, yet mechanisms whereby intracellular Ca2+ may directly modulate Na channel function have yet to be identified. Here we show that calmodulin (CaM), a ubiquitous Ca2+-sensing protein, binds to the carboxy-terminal 'IQ' domain of the human cardiac Na channel (hH1) in a Ca2+-dependent manner. This binding interaction significantly enhances slow inactivation-a channel-gating process linked to life-threatening idiopathic ventricular arrhythmias. Mutations targeted to the IQ domain disrupted CaM binding and eliminated Ca2+/CaM-dependent slow inactivation, whereas the gating effects of Ca2+/CaM were restored by intracellular application of a peptide modelled after the IQ domain. A naturally occurring mutation (A1924T) in the IQ domain altered hH1 function in a manner characteristic of the Brugada arrhythmia syndrome, but at the same time inhibited slow inactivation induced by Ca2+/CaM, yielding a clinically benign (arrhythmia free) phenotype.     

强S一闭空间

本文从强半开集出发，定义了强Ｓ一闭空间，讨论了强Ｓ一闭空间的特征，它的半正则化及强Ｓ一闭空间的强半连续象。     

FOXBASE~＋与8031单片机系统的接口设计

本文提出一种ＦＯＸＢＡＳＥ＋关系型数据库管理系统与８０３１单片机系统三硬、软接口设计方法．为单片机应用系统后续数据的处理提供了有效的手段．     

Riding on Tyvek-A Case Study about How a New Material Invented by Western Multinational Company Enters China

This paper is a case study about how a new product developed by Western multinational company enters new market ?the Mainland China. In this study, a new fabric ?DuPont's hi-technical Tyvek?PU Coating, is fashionized and developed into a new fashionable and functional casual-rainwear, using the approach of new product development method ( idea generation; screening; business analysis; development; evaluation and testing; commercialization).     

现代区域地理学初论

现代区域地理学与传统区别在于加强应用性。它强调人与自然环境相互关系，承认区域性质或功能发现的认识过程，提倡理论与方法的现代化与多样化。     

基于B/S模式的年度考核管理系统的设计与实现

本文阐述了新疆师范大学年度考核管理系统的功能、设计与实现。