投资风险度量初探

从证券投资风险的基本含义及其本质属性出发,提出一种新的风险度量方法,并建立包含损失可能性、损失大小、损失易变性和投资者风险偏好系数的风险度量新指标,从而突出了可能损失大小在风险度量中的重要地位。     

坡体稳定性综合评价：以重庆市北温泉公园后坡为例

在实地观测和分析对比的基础上,按地表物质组成和结构将北温泉公园后坡分为5个样区,选取对坡体稳定性影响较大的地质、地貌、气候等5个因素和10个因子,并对因子作4级划分,采用层次分析法确定各参评因素和因子的权重,对5个样区进行定性定量综合评价.     

SF6的单取代和二取代物中^2JFF的半经验计算

运用最大键级杂化轨道这一计算方法，计算并拟合得到单取代和二取代的ＳＦ６衍生物中＾２ＪＦＦ的具体计算公式，由新公式得到的计算值与实验值基本吻合。     

中文图文电视接收系统的设计

提出了一种中文图文电视接收系统的设计原理与实现方法，并给出了样机的主观评价结果     

VRML在机械设计中的应用

虚现实建模语言是描述虚环境中场景的一种标准，利用它可以在Ｉｎｔｅｒｎｅｔ上建立交互式三维多媒体虚拟现实环境，其应用领域非常广泛，文中介绍了它在机械设计方面的应用。     

集成化CAD／CAM系统

论述了CAD／CAM系统集成技术。从CAD／CAM系统集成方法、CAD／CAM系统集成的关键技术，以及基于特征的产品模型建立等方面对CAD／CAM系统集成技术进行了探讨。     

δ—癸内酯的合成研究

报道了用环戊酮与戊醛经缩合，脱水，加氢及Baeyer-Villiger氧化反应合成δ－癸内酯的方法，总产率为51．36％。     

Improvements of the Computerized Data Acquisition System for 25MWt Experimental Facility of Coal-fired MHD Generator

This paper introduces the design and development of a new computerized data acquisition system for the coal-fired magnetohydrodynamical (MHD) electrical power generation experiments. Compared to the previous system, it has a higher sampling rate and an improved simultaneity performance. It also improves the data collection method and sensor design for the measurement of Faraday voltages and Faraday currents. The system has been successfully used in many regular MHD generator tests. It provides an excellent base for the future research and development of the Coal-fired MHD electrical power generation.     

MiR-205 inhibits the invasion and migration of esophageal squamous cell carcinoma by modulating SMAD1 expression

Esophageal squamous cell carcinoma （ESCC） is one of the most lethal cancers worldwide. In this study, we aimed to investigate the underlying mechanisms of metastasis inhibition by miR-205 in ESCC. In microRNA （miRNA） array and quantitative RT-PCR analyses, we found that the expression level of miR-205 was significantly lower in patients with lymph node metastasis compared with that in patients without lymph node metastasis. After transfection of miR-205 mimics or inhibitors into ESCC cell lines, a significant negative correlation was observed between the expression level of miR-205 and Smad 1. In luciferase reporter assays, we revealed that miR- 205 inhibited the expression of SMAD1 by targeting the 3＇ untranslated region （3＇-UTR） of SMAD1 mRNA in ESCC cells. Furthermore, our results showed that miR-205 sup- pressed the invasion and migration of ESCC cells, whereas Smadl increased their invasion and migration. Taken together, our study demonstrates that miR-205 functions as a suppressor of tumor metastasis by regulating SMAD1 expression through targeting the 3＇-UTR of SMAD1 mRNAin ESCC. Therefore, miR-205 may be a potential therapeutic target for miRNA-based therapy of ESCC.