Inhibitory effect of the adenovirus type 5 E1A protein expressed in the yeast system

The human adenovirus type 5 E1A, a tumor- suppressor gene[1], codes for two major related proteins of 243 amino acids (12S) and 289 amino acids (13S) by al-ternative splicing in two exons[2]. Studies have been shown that E1A can regulate expression of many genes and cell cycle[3]. Both in vitro and in vivo experiments indicated that E1A could induce tumor cells differentia-tion, convert tumor cells into an epithelial phenotype, in-hibit tumor cell growth and metastasis and strongly en-ha…     

Review on aggregation of acid extractants in solvent extraction of metal ions: remark on the general model

The aggregation behavior of various acid extractants in the solvent extraction systems of metal ions is re-examined and explained according to knowledge obtained in recent work. The conclusions are as follows. (1) Complexes formed by the extractants and metal ions can form reversed micelles in organic diluents, depending on the microstructures of the complexes. The dimers of the acid extractant cannot percolate to the metal-extractant aggregates, and the acid-salt complexes are always formed in the aggregates. The reversed micelles or the W/O microemulsions formed by different species cannot be associated with each other to form a unified aggregate. (2) In solvent extraction systems, hydration of the extractants and metal ions can be considered as the driving force of forming reversed micelles. (3) Information of the first approach to the insight of the bicontinuous microemulsion of NaDEHP shows that various components in the aqueous phase behave confined and very similar to the typical AOT/n-heptane W/O microemulsions. (4) In the extraction of lanthanide ions by the W/O microemulsion of sodium naphthenate, the saponification is a process of forming reversed micelle or W/O microemulsion, while the extraction step is a process of destroying reversed micelles or W/O microemulsion droplets.     

Implementation of the finite deformation plastic theory-Tensor derivative and metal forging simulation

It has been shown that the traditional small deformation plasticity can be transplanted to the finite deformation plasticity by using the logarithmic strain measure only. In this way, the mathematical problem of how to find the derivative of a tensor function arises. In this paper, a general method for finding the derivative of a tensor function is proposed. Several metal forging examples are given.During the calculation, the mesh regeneration is not even invoked.     

叠加势V(r)=A_1r~6+A_2r~2+B_2r~(-4)+B_1r(-6)径向Schrdinger方程的解析解

采用连分法得到了幂函数与逆幂函数V(r)=A1r6+A2r2+B2r-4+B1r-6的叠加势径向Schrodinger方程的 解析解.     

地球上远程抛射体的运动轨迹及计算机模拟

本导出了远程抛射体的运动轨迹，建立了一种计算机模拟实验的方法并画出了轨道图像．为理论研究提供了一种实验方法．     

视网膜振荡电位异常改变的临床分析

目的 对多种眼科疾病进行视网膜振荡电位(Ops)的检测及分析，探讨了视网膜振荡电位在眼科多种疾病的诊断及评估方面的临床意义。方法对261例412只眼进行Ops检测，对Ops的检测结果进行分析。结果发现糖尿病及糖尿病性视网膜病变、视网膜中央及分支静脉阻塞、高度近视及高度近视性视网膜病变、视网膜色素变性等均有不同程度的Ops总幅值改变。同时发现，老年性黄斑变性、老年性白内障、弱视、中心性浆液性视网膜脉络膜病变及轻、中度近视者，则Ops总幅值无明显改变。结论视网膜Ops的检测是临床眼科诊断及评估的有力手段。     

利用GMS—5红外资料进行云的分类识别

利用GMS－5 3个红外通道（2个分裂窗区通道和1个水汽通道）的亮温资料，依据各种云不同的辐射特征对其进行分类，由此识别出积雨云（Cb）、浓积云（Cg）、卷云（Ci）、积云（Cu）、中云（Cm）、密云（Dense）等6种主要云类以及雾（Fog）和晴空区域。结合安徽寿县地面观测基准站1998年6、7月份的地面观测资料，对分类结果进行了检验，得到了较为令人满意的结果，准确率接近70％。     

Impact of the closure of Indonesian seaway on climate: A numerical modeling study

Using a global OGCM and its relevant coupled ocean-atmosphere GCM with the contemporary, 6 MaBP and 14 MaBP oceanic topography, respectively, a series of numerical experiments are implemented in order to investigate the effect of the north shift of Australian continent on the tropical oceanic circulation, especially the formation of the western Pacific warm pool. The numerical experiments of the individual OGCM forced by the modern atmospheric circulation indicate that the closure of Indonesian passage results in warming in the tropical Pacific Ocean and cooling in the tropical Indian Ocean; furthermore, it also results in change in source of the Indonesian Through Flow (ITF) water, e.g. ITF mainly originates from the south Pacific at 14 MaBP, but it mainly originates from the north Pacific now. The coupled model shows similar results as the individual OGCM qualitatively.     

Disaster Reduction Decision Support System Against Debris Flows and Landslides Along Highway in Mountainous Area

Highways in mountainous areas are easy to be damaged by such natural disasters as debris flows and landslides and disaster reduction decision support system (DRDSS) is one of the important means to mitigate these disasters. Guided by the theories and technologies of debris flow and landslide reduction and supported by geographical information system (GIS), remote sensing and database techniques, a DRDSS against debris flow and landslide along highways in mountainous areas has been established on the basis of such principles as pertinence, systematicness, effectiveness, easy to use, open and expandability. The system consists of database, disaster analysis models and decisions on reduction of debris flows and landslides, mainly functioning to zone disaster dangerous degree, analyze debris flow activity,simulate debris flow deposition and diffusion, analyze landslide stability, select optimal highway renovation scheme and plan disaster prevention and control ergineering. This system has been applied successfully to the debris flow and landslide treatment works along Palongzangbu Section of Sichuan-Tibet Highway.     

口服转胸腺素α1基因聚球藻对小鼠T细胞亚群作用的研究

为探讨口服后转胸腺α1(Tα1)基因聚球藻对T细胞亚群的作用,将小鼠随机分为空白对照组、野生藻组、转化藻(小剂量、中剂量和大剂量)组和日达仙组,用灌服的方式,给予空白对照组20mL·kg~(-1)的生理盐水,野生藻组0.4g·kg~(-1)的野生聚球藻;转化藻小、中、大剂量组,分别0.2g·kg~(-1)、0.4g·kg~(-1)和0.6g·kg~(-1)的转Tα1基因聚球藻;日达仙组则肌注给予3.2mg·kg~(-1)的胸腺素α1(日达仙)。结果表明转Tα1基因藻口服后可显著提高CD3亚群水平,显著提高CD4亚群水平,明显提高CD4/CD8的比值。提示转Tα1基因聚球藻具有增强机体免疫功能的作用。