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71.
Urinary excretion of glycated albumin was quantitated in genetically hyperglycemic mice (C57BL-Ks-J, db/db mice), a model for non-insulin-dependent diabetes mellitus, and compared with their non-diabetic littermates. The data indicated a preferential excretion of glycated albumin in non-diabetic mice. This phenomenon of 'editing' of glycated albumin is decreased significantly in diabetic mice. Quantitative measurements of overall excretion of glycated albumin suggested that the loss of editing in diabetic mice is due to the dilution of glycated albumin by the unmodified albumin which is excreted in large amounts in diabetic mice. Therefore, the loss of editing observed in this model resembled the one we characterized in insulin-dependent diabetic humans and a streptozotocin-diabetic rat model. 相似文献
72.
By using optical microstructure(OM), X-ray diffractometer analyses and mechanical properties testing, the abnormal damage of pipe coil in remaining heat boiler has been investigated. The damage is the result of the melting of tube base metal at high temperature caused by the ignition inside the tube. 相似文献
73.
根据1986~1987年逐月调查和1987年以来结合教学实习采集的朱家尖海滨底栖无脊椎动物资料,并参考前人对该岛的调查,叙述了朱家尖岛海滨底栖无脊椎动物10门257种,分析了生活潮区、栖息底质等,提出了该岛潮间带生物资源保护的建议。 相似文献
74.
Nicholas R. Farnum 《Journal of forecasting》1992,11(1):47-56
When using simple exponential smoothing on a given time series the nature of the relationship between the optimal smoothing constant and the autocorrelation structure of the series remains an unresolved question. Although numerical search routines can easily be used to find optimal values of the smoothing constant, they offer little insight into the nature of the relationship between the estimated smoothing constant and the structure of the underlying time series. We suggest that renewed investigations of the ex-post sum of squares function may prove helpful in this pursuit. Results are presented that illustrate how the optimal smoothing constant depends upon the value used to initialize the smoothing and upon the sample autocorrelation coefficients of the observed series. These results are based on a new formula for the derivative of the ex-post sum of squares function. In particular, the derivative is examined near 0 and 1, where great simplifications occur in its form, thereby facilitating investigations near these points. A necessary and sufficient condition is stated for when the ex-post sum of squares must have a positive derivative at 0 and the autocorrelation coefficients of the differenced series are shown to affect the sign of the derivative near 1. Based on these results, a general algorithm is presented as an alternative to grid search routines for minimizing the ex-post sum of squares. 相似文献
75.
本文讨论一些Fuzzy映象的重合度的存在性,得出了一些新的重合度定理.本文所得结果统一和发展了引文[5~9]中的许多重要结果. 相似文献
76.
为了得到高反射率的回归反射涂层产品,本项目通过大量实验,生产出最佳的粘合剂及优选出其用量,并利用扫描电镜照片进行了分析。 相似文献
77.
本文研究了枯草杆菌AS1.398发酵培养制备中性蛋白酶,对发酵培养基配比,培养条件,金属离子的影响等进行了摇瓶试验。制备的AS1.398中性蛋白酶有如下性质:最适PH7.2-7.4,在PH6.5-8.0稳定。最适温度42-44℃,35℃下处理2小时能保持约85%酶活力,60℃下10分钟酶完全失活,此酶被EDTA和Cu2+所抑制 相似文献
78.
将快速傅里叶变换技术和数字滤波器设计技术应用于铝电解过程控制信号的滤波与噪声解析模型中,在160kA中间点式下料预焙槽上的试验结果表明了模型的有效性。 相似文献
79.
Nuclear localization and signalling activity of phosphoinositidase C beta in Swiss 3T3 cells. 总被引:14,自引:0,他引:14
The hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdInsP2) is a widespread receptor-coupled signalling system at the plasma membrane of most eukaryotic cells. The existence of an entirely separate nuclear phosphoinositide signalling system is suggested from evidence that purified nuclei synthesize PtdInsP2 and phosphatidylinositol 4-phosphate (PtdInsP) in vitro and that a transient decrease in the mass of these lipids occurs when Swiss 3T3 cells are cultured in the presence of insulin-like growth factor-1 (IGF-1). These IGF-1-dependent changes in inositol lipids coincide with an increase in nuclear diacyglycerol and precede translocation to the nucleus and activation of protein kinase C (refs 5, 6). Circumstantial evidence that links these changes with mitosis comes from the isolation of a 3T3 clone that expresses the type-1 IGF receptor and binds IGF-1 peptide but does not respond mitogenically or show transient mass changes in nuclear inositol lipids. A key question is how IGF-1 initiates the rapid breakdown of PtdInsP and PtdInsP2 in the nucleus. Here we present evidence that nuclei of 3T3 cells contain the beta-isozyme of phosphoinositidase C, whereas the gamma-isozyme is confined to the cytoplasm and that IGF-1 treatment stimulates exclusively the activity of nuclear phosphoinositidase C. 相似文献
80.
非线性生物种群方程解的性质 总被引:1,自引:0,他引:1
讨论一类非线性生物种群方程,证明了解的存在性和唯一性,同时,讨论了系统的稳定性,利用临界增生率,得到了系统渐近稳定、不稳定的充分条件. 相似文献