The industrial asymmetry of the stock price prediction with investor sentiment: Based on the comparison of predictive effects with SVR

As a representative emerging financial market, the Chinese stock market is more prone to volatility because of investor sentiment. It is reasonable to use efficient predictive methods to analyze the influence of investor sentiment on stock price forecasting. This paper conducts a comparative study about the predictive performance of artificial neural network, support vector regression (SVR) and autoregressive integrated moving average and selects SVR to study the asymmetry effect of investor sentiment on different industry index predictions. After studying the relevant financial indicators, the results divide the Shenwan first-class industries into two types and show that the industries affected by investor sentiment are composed of young companies with high growth and high operative pressure and there are a great number of investment bubbles in those companies.     

Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

Atopic disease, including atopic dermatitis (eczema), allergy and asthma, has increased in frequency in recent decades and now affects approximately 20% of the population in the developed world. Twin and family studies have shown that predisposition to atopic disease is highly heritable. Although most genetic studies have focused on immunological mechanisms, a primary epithelial barrier defect has been anticipated. Filaggrin is a key protein that facilitates terminal differentiation of the epidermis and formation of the skin barrier. Here we show that two independent loss-of-function genetic variants (R510X and 2282del4) in the gene encoding filaggrin (FLG) are very strong predisposing factors for atopic dermatitis. These variants are carried by approximately 9% of people of European origin. These variants also show highly significant association with asthma occurring in the context of atopic dermatitis. This work establishes a key role for impaired skin barrier function in the development of atopic disease.     

A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis

To identify susceptibility loci for ankylosing spondylitis, we performed a two-stage genome-wide association study in Han Chinese. In the discovery stage, we analyzed 1,356,350 autosomal SNPs in 1,837 individuals with ankylosing spondylitis and 4,231 controls; in the validation stage, we analyzed 30 suggestive SNPs in an additional 2,100 affected individuals and 3,496 controls. We identified two new susceptibility loci between EDIL3 and HAPLN1 at 5q14.3 (rs4552569; P = 8.77 × 10(-10)) and within ANO6 at 12q12 (rs17095830; P = 1.63 × 10(-8)). We also confirmed previously reported associations in Europeans within the major histocompatibility complex (MHC) region (top SNP, rs13202464; P < 5 × 10(-324)) and at 2p15 (rs10865331; P = 1.98 × 10(-8)). We show that rs13202464 within the MHC region mainly represents the risk effect of HLA-B*27 variants (including HLA-B*2704, HLA-B*2705 and HLA-B*2715) in Chinese. The two newly discovered loci implicate genes related to bone formation and cartilage development, suggesting their potential involvement in the etiology of ankylosing spondylitis.     

短消息在交通信息发布系统中的应用与研究

为满足出行者对实时交通信息的需求,在已获得交通信息的基础上,结合出行者需求的个性化、多样化等特点,研究了实时交通信息的短消息动态发布模式。以通用SMIP协议为承载,采用自定义的应用层协议;设计伺服和推送两种发布服务方式,达到更好的手机终端与交通信息平台之间的信息协同效果。最后,以Java开源软件为平台开发交通信息的短消息动态发布子系统,使已有交通信息发布系统的基本功能得到进一步的拓展。     

喀斯特山地不同退化植被下烟管荚蒾氮同位素组成的季节变化

为探讨喀斯特灌木丛优势树种烟管荚蒾(Viburnum utile)叶片稳定氮同位素组成的季节变异特征及其影响因素,以喀斯特高原贵州省清镇市王家寨峰丛洼地小流域为例,选取流域内稀疏灌草丛、草灌丛、灌丛3种植被类型下的常绿树种烟管荚蒾为具体研究对象,分别在4月(生长初期)、7月(生长旺盛期)、9月(生长晚期)和12月(生长停滞期)对其叶片稳定氮同位素组成和N、P、K、Ca、Mg、Fe、Mn、Cu、Zn元素含量进行测定分析。结果表明:研究区烟管荚蒾叶片的δ~(15)N在不同群落间和不同坡位间均无显著差异(P0.05),群落间的变化趋势为灌丛稀疏灌草丛草灌丛,坡位间的变化趋势为中坡下坡上坡,变化范围为-3.28‰～-0.59‰,平均值为-2.22‰;烟管荚蒾叶片δ~(15)N值在不同群落中均表现出9月最负而12月最正的特征,变化趋势均为9月7月12月,但仅在草灌丛群落中的7月与12月间和9月与12月间有显著差异(P0.05),在其他群落中各月份间的差异均不显著(P0.05),同一生长期内不同群落间、不同坡位间的差异也不显著;研究区植被类型、坡位和季节对烟管荚蒾叶片δ~(15)N的交互影响均不显著,说明烟管荚蒾对生境恶劣的喀斯特环境具有特殊的适应能力;烟管荚蒾叶片的δ~(15)N与Fe、Mn含量密切相关,同时受N、P、K、Fe、Mn、Cu、Zn元素化学计量比的影响,说明其叶片δ~(15)N值的变化主要受自身氮生理代谢过程的控制;研究区9月温暖湿润和12月干旱寒冷的气候特征可能是导致烟管荚蒾叶片δ~(15)N在9月最负和12月最正的主要原因。     

论城市商业中心的旅游空间营造——以重庆市沙坪坝区三峡广场为例

旅游空间的规划设计对商业中心的可持续发展具有十分重要的推动作用,但对商业中心旅游空间的研究并不多.从分析重庆市沙坪坝区三峡广场旅游空间的现状及生存问题出发,采用借空间的思想,发挥空间思维的想象力;接着在图底理论、联系理论、场所理论3大理论基石的基础上营造三峡广场的旅游空间;最后从物质性空间与非物质性空间的角度深入解剖了广场旅游空间营造的相关因子及营造体系.通过对三峡广场旅游空间的营造,不仅有利于增加当地居民的游憩与休闲场所,也扩大了旅游者购物、娱乐的内容,对三峡广场的多样化、可持续发展有十分重要的意义;同时对其他类似商业中心的生产发展也具有十分重要的借鉴作用.     

Synthesis and luminescence properties of Mn4+-dopant Ca14Zn6Ga10−xAlxO35 solid solution

Mn~(4+)-activated oxide phosphors,owing to their desirable spectral features,eco-friendly and low cost,are emerging as a new class of non-rare-earth red phosphors for warm white LEDs.However,these phosphors possess low photoluminescence quantum efficiency excited by blue chip currently.Herein we report an isostructural solid solution of Ca_(14)Zn_6Ga_(10-x)Al_xO_(35):0.15Mn~(4+)(0≤x≤10)synthesized by a traditional solidstate reaction route.The microstructure and luminescent performance of this red-emitting phosphor are investigated in detail with the aids of X-ray diffraction,diffuse reflection spectra,photoluminescence spectra/decay/QE,and temperature-dependent PL/QE measurements.Blue shift of energy peaks of~4A_2→~4T_1and~4A_2→~4T_2transition is illustrated by the Tanabe–Sugano diagram and the configurational coordinate diagram.The crystal field strength(Dq)and the Racah parameters(B and C)are carefully calculated to estimate the nephelauxetic effectβrespectively.Particularly we achieve external and internal quantum efficiencies as high as26.1%and 40.3%for Ca_(14)Zn_6Ga_6Al_4O_(35):0.15Mn~(4+)excited by 466 nm,the highest one ever reported in Mn~(4+)activated oxide phosphors under the similar condition.     

浅谈声乐教育中的心理因素

本文认为,心理在声乐教学中的地位非常重要,在声乐教育中应该注意对学生心理情感的培养.     

煤矿瓦斯事故的原因及遏制对策探讨

在煤矿矿井中,瓦斯灾害主要表现为瓦斯爆炸(瓦斯煤尘爆炸)和煤与瓦斯突出事故.瓦斯事故的发生,不仅使国家的生命财产遭受重大损失,而且影响煤炭生产正常进行,如何控制和防止瓦斯爆炸事故是搞好当前煤矿安全一项重要任务.