Human infection by genetically diverse SIVSM-related HIV-2 in west Africa.

Our understanding of the biology and origins of human immunodeficiency virus type 2 (HIV-2) derives from studies of cultured isolates from urban populations experiencing epidemic infection and disease. To test the hypothesis that such isolates might represent only a subset of a larger, genetically more diverse group of viruses, we used nested polymerase chain reactions to characterize HIV-2 sequences in uncultured mononuclear blood cells of two healthy Liberian agricultural workers, from whom virus isolation was repeatedly unsuccessful, and from a culture-positive symptomatic urban dweller. Analysis of pol, env and long terminal repeat regions revealed the presence of three highly divergent HIV-2 strains, one of which (from one of the healthy subjects) was significantly more closely related to simian immunodeficiency viruses infecting sooty mangabeys and rhesus macaques (SIVSM/SIVMAC) than to any virus of human derivation. This subject also harboured multiply defective viral genotypes that resulted from hypermutation of G to A bases. Our results indicate that HIV-2, SIVSM and SIVMAC comprise a single, highly diverse group of lentiviruses which cannot be separated into distinct phylogenetic lineages according to species of origin.     

求解具有终端约束两点边值问题的一种迭代法

本文提出了一个用反向延拓法求解两点边值问题的一种迭代法。由系统的动态方程,导出了边界变量所满足的微分方程,而且又由终端约束导出了边界变量偏导数的表达式。有了边界变量偏导数的终端值以及它们适合的微分方程,就可以由终端反向积分这些微分方程求解出这些变量来。利用上述想法,构成了一种求解两点边值问题的迭代法。     

水资源永续支持区域经济发展的理论与实践

从基本概念入手，界定了水资源、区域经济可持续发展、水资源永续支持的新内涵，提出了水资源永续支持区域经济发展的理论，包括区域经济可持续发展理论、水资源永续利用理论、水资源支持经济发展理论和水资源永续支持协调决策理论。在此基础上构建了水资源永续支持区域经济发展模型，并以陕北能源基地为实例，对理论和模型进行了验证。     

Ramsey数的下界

本文由构造循环图得到 Ramsey 数 r(3,q)的下界渐近公式,并且在 Ramsey 循环图的基础上构图,改进了 Ramsey 数 r(3,10)和 r(3,12)的下界。     

一类高阶多变量的非线性伪双曲方程组的周期边值问题与初值问题

本文利用能量积分估计Leray—Schauder不动点证明了一类高阶多变量的非线性伪双曲方程组的周期边值问题和初值问题广义解的存在性与唯一性.     

节水洗衣机的最优运行模型

在不考虑时间、温度情况下,我们讨论了洗衣机用水量与洗涤次数的关系,得出了解析式,并给出了总用水量最小值的每次加水量一定条件下成立的定理,并据解析式,列出了数据表格、讨论给出了最佳节水洗涤方案,分析了实验数据Ｕ、ＶｇＱ对结果影响,在推广中讨论了Ｖｇ的其它确定方式及自动控制洗涤次数的方案。     

Nonlinear phenomena of three-dimensional liquid sloshing in microgravity environment

In astronautic engineering, propellant sloshing, i.e. the oscillatory motion of a liquid propellant in a mov- ing container, is a subject of great importance[1―17]. Sloshing has an unfavorable influence on spacecraft stability and may disturb the flight …     

黄芪、川芎嗪治疗原发性肾病综合征临床分析

对原发性肾病综合征在肾上腺皮质激素治疗过程中辅以黄芪、川芎嗪治疗,结果表明治疗组总有效率83.4％,对照组总有效率56.7％,提示黄芪、川芎嗪联合激素治疗原发性肾病综合征,在提高血浆白蛋白、降低尿蛋白、降血脂、改善血液高凝状态等方面明显优于单用激素治疗组,可迅速缓解临床症状,减少激素用量,提高激素的疗效.