Interaction of SynaptotagminⅠ with Phospholipid Membrane: A Monolayer Study

IntroductionSynaptotagmin is a family of vesicletransmembrane proteins present in synapticvesicles and large secretary granules of neuronsand endocrine cells[1 ] .It is a major constituent ofsynaptic vesicle membranes,comprising7% 8%of the total vesicle protein,characterized by ashort intravesiclar N-terminus,a singletransmembrane region,and a long plasmicdomain.　The best-charaterized form of synaptotagmin,syt ,is found abundantly in rostrol brain.Syt was first described in 1 981 [2 ] ,and i…     

传统：排斥与融合的变奏

任何一个民族的"大传统"都包含着许多"小传统",它们之间的相互隔绝相互排斥,以及相互沟通相互融合,推进着人类思想文化传统的演进。在我们身边,对待传统有两种极端的态度,对传统的迷恋崇拜,与激烈地反对传统。对于这些态度,我们需要作仔细的分析。     

A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules

Assembly of class I major histocompatibility complex (MHC) molecules involves the interaction of two distinct polypeptides (the heavy and light chains) with peptide antigen. Cell lines synthesizing both chains but expressing low levels of MHC class I molecules on their surface as a result of a failure in assembly and transport have been identified. We now report that although the apparent steady-state distribution in these cells of class I molecules is in the endoplasmic reticulum (ER), the molecules in fact are recycled between the ER and Golgi, rather than retained in the ER. This explains the failure of class I molecules to negotiate the secretory pathway. Class I molecules do not seem to be modified by Golgi enzymes, suggesting that the proteins do not reach the Golgi apparatus during recycling. But morphological and subcellular fractionation evidence indicates that they pass through the cis Golgi or a Golgi-associated organelle, which we postulate to be the recycling organelle. This compartment, which we call the 'cis-Golgi network', would thereby be a sorting organelle that selects proteins for return to the ER.     

微机扭矩仪与苹果机的联机通信

介绍了苹果机与微机扭矩仪之间联机通信的方法，同时阐述了ＢＡＳＩＣ语言与汇编语言混合编程的技巧。     

流变学中的十大难题

本文在论述流变学的过去与现状后,提出了现今存在的十个困难问题。从而,表明发展流变学的关键研究方向。     

一类无理数的推广

1984年Bundschuh[2]证明了:设整数g≥2,则 a_h(g)=0.(g~0)_h(g~1)_h(g~2)_h……是无理数。这里(g~n)_h是幂g~n在h进制中写出的数字。他所用的方法既复杂又牵涉更高深的p-adic理论。我们发现这个定理可以推广到具有正的上密率的数列上去,而且证明方法只用到一些较初等知识就行了。     

《孙子兵法》在体育教学中的运用

《孙子兵法》虽为古代兵书，但它所蕴含的军事、哲学、管理等思想也适用于体育教学，对于体育教师的教学有很好的借鉴和指导作用。从“五事七计”的内容论述教学之道，以计为首；体育教师要具备的基本素质是智、信、仁、勇、严；备课要做到“知彼知己、百战不殆”；教学管理体现“令之以，齐之以武”的原则；利用“造势”来创造良好的课堂教学气氛。     

谈企业文化的经济效益

对企业文化的清晰解读就是经济效益。科学的企业文化是实用的,经济利益的持续健康增长是企业文化建设的根本目的。即企业通过对内的整合达到对外部竞争环境的适应,提高组织运作效率,塑造整体形象,提高企业核心竞争能力,实现转换。     

化学振荡速率常数的研究

根据振荡反应中存在着活性中心的观点．在大量实验数据的基础上，推导出振荡反应速率常数的计算公式。