Null controllability of some degenerate wave equations

This paper is devoted to a study of the null controllability problems for one-dimensional linear degenerate wave equations through a boundary controller. First, the well-posedness of linear degenerate wave equations is discussed. Then the null controllability of some degenerate wave equations is established, when a control acts on the non-degenerate boundary. Different from the known controllability results in the case that a control acts on the degenerate boundary, any initial value in state space is controllable in this case. Also, an explicit expression for the controllability time is given. Furthermore, a counterexample on the controllability is given for some other degenerate wave equations.     

“文革”时期高校科技期刊与其科学史研究

"文革"时期的期刊传播由于时代的特殊性而呈现与前后截然不同的传播范式,而在"文革"时期"如火如荼"的科学史研究,尤其是中国古代科学技术史的研究,是这个时代的"副产品"。虽然处于政治高压之下,"批林批孔"、批儒尊法是主要目的,但这一时期的科学史研究承上启下,为之后中国第二次科学史研究高潮的出现作了重要铺垫。     

气体扩散层亲疏水特性对流体分布的预测

采用伪势两相格子玻尔兹曼方法（LBM）研究了非增湿条件下碳纸和碳布气体扩散层（GDL）的流体流动状态。通过随机方法和X射线扫描法构建了气体扩散层样本。为确保模型中表面张力和接触角计算的准确性，采用玻璃微珠模型进行验证，随后通过调整气体扩散层的亲疏水特性，分析流体在气体扩散层中流动的实时状态，得到了亲疏水特性对孔隙结构内水饱和度的影响规律。结果表明：疏水性气体扩散层中的水分布与亲水性气体扩散层中的水分布明显不同，较大的疏水性更有利于气体扩散层内水的排出；疏水性更强的气体扩散层显著提高了液态水进入气体扩散层的入口压力，导致催化剂层（CL）更容易受到水渗透的影响。     

New rapid transfer alignment method for SINS of airborne weapon systems

Transfer alignment is an effective alignment method for the strapdown inertial navigation system （SINS） of airborne weapon systems. The traditional transfer alignment methods for large misalignment angles alignment use nonlinear transfer align- ment models and incorporate nonlinear filtering. A rapid transfer alignment method with linear models and linear filtering for ar- bitrary misalignment angles is presented. Through the attitude quaternion decomposition, the purpose of transfer alignment is converted to estimate a constant quaternion. Employing special manipulations on measurement equation, velocity and attitude linear measurement equations are derived. Then the linear trans- fer alignment model for arbitrary misalignment angles is built. An adaptive Kalman filter is developed to handle modeling errors of the measurement noise statistics. Simulation results show feasibili- ty and effectiveness of the proposed method, which provides an alternative rapid transfer alignment method for airborne weapons.     

Single cell biology beyond the era of antibodies: relevance,challenges, and promises in biomedical research

Research of the past two decades has proved the relevance of single cell biology in basic research and translational medicine. Successful detection and isolation of specific subsets is the key to understand their functional heterogeneity. Antibodies are conventionally used for this purpose, but their relevance in certain contexts is limited. In this review, we discuss some of these contexts, posing bottle neck for different fields of biology including biomedical research. With the advancement of chemistry, several methods have been introduced to overcome these problems. Even though microfluidics and microraft array are newer techniques exploited for single cell biology, fluorescence-activated cell sorting (FACS) remains the gold standard technique for isolation of cells for many biomedical applications, like stem cell therapy. Here, we present a comprehensive and comparative account of some of the probes that are useful in FACS. Further, we illustrate how these techniques could be applied in biomedical research. It is postulated that intracellular molecular markers like nucleostemin (GNL3), alkaline phosphatase (ALPL) and HIRA can be used for improving the outcome of cardiac as well as bone regeneration. Another field that could utilize intracellular markers is diagnostics, and we propose the use of specific peptide nucleic acid probes (PNPs) against certain miRNAs for cancer surgical margin prediction. The newer techniques for single cell biology, based on intracellular molecules, will immensely enhance the repertoire of possible markers for the isolation of cell types useful in biomedical research.     

2002-2012年中国林学基础研究热点分析——基于国家自然科学基金申请项目和资助项目关键词的研究

本文通过对2002-2012年国家自然科学基金委员会林学学科申请和资助项目的关键词进行共词分析,剖析了各关键词之间的关系,并借助对高频关键词的聚类分析和多维尺度分析,揭示了这11年来林学学科基础研究的热点及其内涵,探讨了目前被科学家忽视的重要科学问题.这一分析将为做好林学学科布局,促进学科均衡持续发展提供帮助.     

Routes and machinery of primary cilium biogenesis

Primary cilia are solitary, microtubule-based protrusions of the cell surface that play fundamental roles as photosensors, mechanosensors and biochemical sensors. Primary cilia dysfunction results in a long list of developmental and degenerative disorders that combine to give rise to a large spectrum of human diseases affecting almost any major body organ. Depending on the cell type, primary ciliogenesis is initiated intracellularly, as in fibroblasts, or at the cell surface, as in renal polarized epithelial cells. In this review, we have focused on the routes of primary ciliogenesis placing particular emphasis on the recently described pathway in renal polarized epithelial cells by which the midbody remnant resulting from a previous cell division event enables the centrosome for initiation of primary cilium assembly. The protein machinery implicated in primary cilium formation in epithelial cells, including the machinery best known for its involvement in establishing cell polarity and polarized membrane trafficking, is also discussed.     

Backstepping approach to the adaptive regulator design for a one-dimensional wave equation with general input harmonic disturbance

This paper considers the parameter estimation and stabilization of an unstable one-dimensional wave equation with matched general harmonic disturbance at the controlled end. The backstepping method for infinite-dimensional system is adopted in the design of the adaptive regulator. It is shown that the resulting closed-loop system is asymptotically stable. Meanwhile, the estimated parameter is shown to be convergent to the unknown parameter as time goes to infinity.