Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting.

Interleukin-2 (IL-2) is a lymphocytotropic hormone which is thought to have a key role in the immune response of mammalian cells. It is produced by a subpopulation of activated T-lymphocytes and acts in vitro as the principal auto- and paracrine T-cell growth factor (for reviews see refs 1-3). IL-2 is, however, not the sole T-cell growth factor, nor does it act exclusively on T cells, also promoting growth of NK cells and differentiation of B cells. A role for IL-2 in T-cell development has been postulated but remains controversial. Here we test the requirement for IL-2 in vivo using IL-2-deficient mice generated by targeted recombination. We find that mice homozygous for the IL-2 gene mutation are normal with regard to thymocyte and peripheral T-cell subset composition, but that a dysregulation of the immune system is manifested by reduced polyclonal in vitro T-cell responses and by dramatic changes in the isotype levels of serum immunoglobulins.     

基于强跟踪滤波器估计的最优融合方法

在分布式雷达数据处理模式中 ,数据融合是获得较精确的目标轨迹的主要环节。为克服卡尔曼滤波器对初始值敏感、鲁棒性差和对机动目标跟踪性能差的缺陷 ,通过利用各传感器的观测数据 ,采用强跟踪滤波器对目标进行跟踪 ,以改善目标状态估计的精度。对判定源于同一目标的状态估计值 ,给出了一种估计状态线进行性组合的最优融合准则。得出了实际数据的实验结果。     

可编程控制器调速器

本文以联合研制成功的水电站可编程控制调速器为对象，详细介绍其硬件与软件构成及工作原理。同时，对多种调节模式等方面也进行了一些探索。     

高含固量聚苯乙烯－聚丙烯酸酯复合乳胶的合成及表征

本文采用种子乳液聚合技术，合成聚苯乙烯－聚丙烯酸酯复合乳液，用ＴＥＭ电镜观察其乳液的形态，用ＧＰＣ方法测定了乳胶聚合物的化学组成。     

AC=BD在微分方程中的应用

利用AC＝BD的思想，将变系数广义KdV方程约化成常微分方程，求出了KdV方程的Lax对。     

A small GTP-binding protein dissociates from synaptic vesicles during exocytosis.

Low-molecular-weight GTP-binding proteins are strong candidates for regulators of membrane traffic. In yeast, mutations in the sec4 or ypt1 genes encoding small GTP-binding proteins inhibit constitutive membrane flow at the plasma membrane or Golgi complex, respectively. It has been suggested that membrane fusion-fission events are regulated by cycling of small GTP-binding proteins between a membrane-bound and free state, but although most of these small proteins are found in both soluble and tightly membrane-bound forms, there is no direct evidence to support such cycling. In rat brain a small GTP-binding protein, rab3A, is exclusively associated with synaptic vesicles, the secretory organelles of nerve terminals. Here we use isolated nerve terminals to study the fate of rab3A during synaptic vesicle exocytosis. We find that rab3A dissociates quantitatively from the vesicle membrane after Ca2(+)-dependent exocytosis and that this dissociation is partially reversible during recovery after stimulation. These results are direct evidence for an association-dissociation cycle of a small GTP-binding protein during traffic of its host membrane.     

实验选课系统的设计及实现

在实行学分制的情况下,配合校级中心实验室的管理模式和实验室管理软件进行设计和开发的实验选课系统,既适应了学分制的要求,完善了实验室的管理机制,也提高了管理水平和工作效率。     

井冈山斗争时期党政组织综述

井冈山斗争时期共产党的政权组织主要有湘赣边秋收起义前委、红四军军委、湘赣边特委等11个;苏维埃政府主要有茶陵县工农兵苏维埃政府、遂川县工农兵苏维埃政府、湘赣边界工农兵苏维埃政府等7个。     

岩石扩容现象与超声横波特征参数相互关系研究评述

介绍了岩石扩容现象与超声皮特征参数相互关系相关专业领域研究的现状及其应用，在用横波速度最大值（Vsmax）来分析岩石微裂纹初始扩展时的应力值（应力门槛值）新方法的基础上，建议利用主动的人工横波震源，应力门槛值、Vsmax后的横波速度值与岩石裂纹加速发展的同步减小特性，更深入地进入地震破裂丛集及前兆特征的研究，有可能建立地震和地质灾害性预报的新方法，并提出利用利用传统方法研究岩石扩容机理，应力门槛值，泊松比等的同时，进行岩石扩容现象，声发射和超声波横波等特性参相互关系研究的新思路。     

基于IP多播的机房信息管理系统的设计与实现

提出了一种基于IP多播技术的解决方案并加以实现,满足了对上机学生按系或班级分组进行管理与各类统计的需要,实现了传统C/S结构所能实现的全部功能,解决了传统机房信息管理系统使用带来的问题。