Lymphopenia and lymphocyte transformation in alcoholics

Summary The basis of peripheral blood lymphopenia observed in patients with chronic alcoholism and liver disease was investigated by examining the effect of sera of these patients on in vitro transformation of normal human peripheral blood lymphocytes. A positive correlation was demonstrated between the serum inhibition of phytohaemagglutinin- and pokeweed mitogen-induced transformation and the degree of lymphopenia. Thus serum factors may contribute to the observed lymphopenia by inhibiting lymphocyte production in vivo.This study was supported by grants from the National Health and Medical Research Council of Australia, Royal Australasian College of Physicians and Alfred Hospital Henry Laurie Scholarship Fund.     

Variance intervention

Variance intervention is a simple state-space approach to handling sharp discontinuities of level or slope in the states or parameters of models for non-stationary time-series. It derives from earlier procedures used in the 1960s for the design of self-adaptive, state variable feedback control systems. In the alternative state-space forecasting context considered in the present paper, it is particularly useful when applied to structural time series models. The paper compares the variance intervention procedure with the related ‘subjective intervention’ approach proposed by West and Harrison in a recent issue of the Journal of Forecasting, and demonstrates it efficacy by application to various time-series data, including those used by West and Harrison.     

Fungitoxicity ofm-fluorophenylalanine-containing peptides towardsPythium ultimum

Summary The tripeptide L-m-fluorophenylalanyl-L-alanyl-L-alanine was much more fungitoxic towardsPythium ultimum than the dipeptide L-m-fluorophenylalanyl-L-alanine orm-fluorophenylalanine. The fungitoxicity of the tripeptide was reduced by L-alanyl peptides and phenylalanine, but not by other amino acids. In contrast, the fungitoxicity ofm-fluorophenylalanine was unaffected by peptides, and was antagonized by several amino acids. These results suggest the effective delivery ofm-fluorophenylalanine into the cell by a tripeptide carrier.     

辐射源个体识别中分类器应用

随着电磁辐射源个体之间差异的减小,传统的模板比对法已经难以完成对辐射源的个体识别任务。为了更好的识别个体之间的微小差异,提高复杂电磁环境中辐射源个体识别的成功率,从工程应用角度出发,提出先使用Fisher判别率进行特征预选,再使用主成份分析进行降维,最后使用支持向量机进行训练识别的辐射源个体识别方法,构建了可以识别辐射源威胁差异的分类器。仿真结果表明:该方法可以兼顾工程应用中识别正确率和识别速度的要求,对辐射源个体识别具有较好的应用价值。     

知识图谱概念获取研究进展

随着Web技术的不断更新与发展,知识图谱以其强大的语义处理能力与开放互联能力吸引了各行各业的关注。各行各业都在纷纷构建所属领域的知识图谱,如何从不同数据源抽取构建知识图谱所需概念,成为知识图谱构建的关键技术,概念抽取得越完整,所构建的知识图谱越全面,利用价值越高。本文对不同数据源抽取知识图谱概念进行阐述说明,以期引导学者选择合理的方法进行学术分析,提升知识图谱应用水平。