A collimated, high-speed outflow from the dying star V Hydrae

Stars with masses in the range 1-8 solar masses (M(\circ)) live ordinary lives for approximately 10(9)-10(10) years, but die extraordinary deaths. First, during their death throes as asymptotic giant branch (AGB) stars they eject, over 10(4)-10(5) years, half or more of their mass in slowly expanding, spherical winds, and then, in a short (a few 100-1,000 years) and poorly understood phase, they are transformed into aspherical planetary nebula. Recent studies support the idea that high-speed, jet-like flows play a crucial role in this transformation. Evidence for such outflows is indirect, however; this phase is so short that few nearby stars are likely to be caught in the act. Here we report the discovery of a newly launched, high-speed jet-like outflow in the nearby AGB star, V Hydrae. We have detected both proper motions and ongoing evolution in the jet. These results support a model in which the jet is driven by an accretion disk around an unseen, compact companion. We also find a central, dense equatorial disk-like structure which may enable and/or enhance the formation of the accretion disk.     

The causes of Charcot-Marie-Tooth disease

Charcot-Marie-Tooth (CMT) disease serves as the summary term for the most frequent forms of inherited peripheral neuropathies that affect motor and sensory nerves. In the last 12 years, 14 genes have been identified that cause different CMT subforms. The genes found initially are predominantly responsible for demyelinating and dysmyelinating neuropathies. Genes affected in axonal and rare forms of CMT have only recently been identified. In this review, we will focus on the currently known genes that are associated with CMT syndromes with regards to their genetics and function.Received 5 April 2003; received after revision 20 May 2003; accepted 23 May 2003     

Management Philosophy and Practices of Habitat Conservation for Jiuzhaigou Nature Reserve, Sichuan, China

Starting from the pressure on habitat of Jiuzhaigou Nature Reserve brought about by traveling activity, this paper puts forward such philosophy of community co-management of conservation-based tourism development for Jiuzhaigou Nature Reserve, According to this philosophy, emphasis is laid on the analysis of the mission of habitat protection, functional division, habitat maintenance, community construction, scientific study and management organization system. The study shows that the close relation and significance of rights and interests shared between nature reserve and resi-dents in community, as well as the value of community comanagement philosophy of conservation-based tourism development in sustainable management of nature reserve, have set an exemplary example for other nature reserves.     

河南鸡公山自然保护区蛇类资源调查

从2000年至2003年对鸡公山自然保护区的蛇类资源进行了调查，共发现蛇类25种．其中有毒蛇5种．无毒蛇20种．调查结果表明．鸡公山境内的蛇类种类和种群数量有增加的趋势。     

信息资源共享的现状和展望

介绍了信息资源共享现状,探讨了信息资源共享系统的评价方法,展望了信息资源共享的发展趋势。     

Distal residues in the oxygen binding site of haemoglobin studied by protein engineering

The geometries of the Fe-O2 and Fe-CO bonds in myoglobin and haemoglobin differ significantly from those in free porphyrin model compounds. It has been suggested that steric hindrance by Val-E11 and His-E7 and a hydrogen bond between His-E7 and oxygen affect the geometry and electronic state of the Fe-ligand bond, and that these interactions may be important in controlling oxygen affinity. We have produced mutant haemoglobins in E. coli having Val(67 beta)E11 replaced by Ala, Met, Leu or Ile and His(58 beta)E7 by Gln, Val or Gly. We have studied the effect of these mutations on the equilibrium and kinetics of ligand binding. The conformation of the new side chains and their effect on the protein structure have been examined by X-ray crystallography, and the vibrational properties of the Fe-CO bond observed by resonance Raman spectroscopy. We found that the steric hindrance of ligand binding by the E11 residue and the polarity of the E7 residue in the beta subunit are critical for fine-tuning ligand affinity.     

Plant genetics: gene transfer from parasitic to host plants

Plant mitochondrial genes are transmitted horizontally across mating barriers with surprising frequency, but the mechanism of transfer is unclear. Here we describe two new cases of horizontal gene transfer, from parasitic flowering plants to their host flowering plants, and present phylogenetic and biogeographic evidence that this occurred as a result of direct physical contact between the two. Our findings complement the discovery that genes can be transferred in the opposite direction, from host to parasite plant.