Characteristics of the binding features of Nelin with F-actin and screening Nelin interactive proteins

The interaction of nelin, a cardiac-specific expressed protein of human novel gene nelin, with F-actin was studied by both F-actin cosedimentation in vitro and colocalization assays. The results showed that nelin is a new F-actin binding protein and is colocolized with F-actin in cytoplasm of cells. Three new nelin binding proteins, filamin C subtype, titin N2B subtype and inter-alpha trypsin inhibitor heavy chain precursor (ITIH), were identified from human heart cDNA library using yeast two-hybrid screening. The binding activity of filamin C with nelin was confirmed by coimmunoprecipitation. Filamin C binds to nelin through its C-terminal region. It is indicated that nelin is a cytoskeleton associated protein and acts as a membrane-cytoskeleton associated protein involved in the formation of focal adhesions.     

国防科研中有关项目选题的探讨

在国防科研领域中 ,项目从选题、投资到研究开发都应遵循内在的科学规律。在分析国防项目主题发展一般规律的基础上 ,就科研项目选题原则和切入点问题展开讨论。引入“两头大象”理论 ,形象地揭示选题的内在依据。最后以一个由师生组成的典型科研小组为背景 ,就工程和基础理论两类研究的投入时机和权重问题建立决策模型 ,并给出了模型的数值结果及一些结论。     

Spontaneous breaking of time-reversal symmetry in the pseudogap state of a high-Tc superconductor

A change in 'symmetry' is often observed when matter undergoes a phase transition-the symmetry is said to be spontaneously broken. The transition made by underdoped high-transition-temperature (high-Tc) superconductors is unusual, in that it is not a mean-field transition as seen in other superconductors. Rather, there is a region in the phase diagram above the superconducting transition temperature Tc (where phase coherence and superconductivity begin) but below a characteristic temperature T* where a 'pseudogap' appears in the spectrum of electronic excitations. It is therefore important to establish if T* is just a cross-over temperature arising from fluctuations in the order parameter that will establish superconductivity at Tc (refs 3, 4), or if it marks a phase transition where symmetry is spontaneously broken. Here we report that, for a material in the pseudogap state, left-circularly polarized photons give a different photocurrent from right-circularly polarized photons. This shows that time-reversal symmetry is spontaneously broken below T*, which therefore corresponds to a phase transition.     

基于个体的两凿岩机械手合作任务规划

文章在分析凿岩机械手的机构结构的基础上,求出机械手在工作面上的最大最小工作区间,然后运用模糊理论的相关知识将两凿岩机械手的工作区间进行合理分区,确定两钻臂在这些区域产生碰撞的模糊隶属度,从而引入"区域避碰”理论进行合作任务规划.在考虑两机械手工作进度产生一定变化和机械手在运动中所有关节变化量最小的基础上,引入双向A*算法搜寻最优路径.通过仿真研究证明,文章提出的方法计算简单,规划的路径在一定程度上可满足实际工作的需要.     

国际互联网技术与旅游业企业过程重组

信息技术、互联网、通讯技术的发展引起了整个旅游业的一场革命,正在深刻地改变着旅游业的经营、管理和运作模式。网络技术的出现则恰好给旅游业的加速发展、企业过程重组带来了新的机遇。文章集中分析了旅游业的信息特征、信息技术、互联网技术引起的旅游业的经营环境变化,提出了旅游服务供应链管理的概念。在此基础上,结合英特网技术在旅游业的功能,提出了旅游业的企业过程重组,建立虚拟旅游公司模式。     

TVOD系统设计

VOD即"按需服务电视".介绍了国外的相关研究工作,指出电视系统不应停留在数字化技术上,而应以此为基础向智能化与Web集成的方向发展.从电视业务级别的划分入手,定义了TVOD的概念,并区别了TVOD与VOD的技术思路和应用范畴.详细讨论了TVOD概念系统的结构和关键技术.     

共轨蓄压式电控泵喷嘴系统的实验研究

研究共轨蓄压式电控泵喷吡系统的喷射特性,取代传统的泵－油管－喷嘴系统,利用研制的实验装置对共轨蓄压式电控泵喷嘴的流量特性、喷油压力特性及喷油定时进行实验,由此分析影响喷射特性的各种因素,实验结果表明,共轨蓄压式电控泵喷嘴的特性不仅受共轨压力、增压时间的影响,转速对其也有一定的影响,而在喷射特性调节的灵活性方面,共轨蓄压式电控泵喷嘴较传统的泵－油管－喷嘴系统有明显改善。     

啤酒酵母对水中Cr（VI）的吸附研究

采用啤酒酵母作吸附剂吸附水中Cr(VI),考察了吸附时间、吸附剂用量、pH值和初始浓度对吸附效果的影响.研究发现,吸附效果受pH值影响最大,当pH值为2~3时Cr(VI)的去除效果最好.啤酒酵母对Cr(VI)的吸附遵循Langmuir和Freundlich等温线方程,符合拟二级动力学模型,实验结果表明啤酒酵母是一种有效去除废水中Cr(VI)的生物吸附剂.     

一种改进的局部对比度图像增强算法

基于加权自适应直方图均衡法,本文提出了一种局部对比度增强算法.它既考虑了图像细节的增强,也考虑了噪声的抑制.针对图像中不同区域存在对比度差异的情况,通过参数设置使高对比度的区域细节增强较少,而低对比度的区域则加大增强细节的力度,从而改善图像视觉效果.由于在图像的增强处理过程中,忽略了对应于原图像中梯度小于某一域值ε的像素的计算,从而减少了图像增强需要的计算量.实验表明算法是有效的.