The Difference of the Pulmonary-Artery Pressure of the Migrants from Difference Elevation at the 4636 - 4907 m Altitude

Study Objective： To compare and analyze the changes of the pulmonary-artery pressure of the migrants coming from different elevation in the hypoxic environment of 4636 - 4907 m extreme altitude. To explore the susceptibility to hypoxic pulmonary-artery hypertension （PH） in the subjects from different altitude and profession. Methods： By using Color Doppler Ultmsonography （CDU）, measuring the pulmonary-artery pressure of 207 healthy men, who had continuously being lived and worked at the extreme altitude for more than six months, and then were divided into three groups according to their profession and the altitude of original living place. Results： There was a significant difference in the outcomes of pulmonary-artery pressure from the 3 groups. Conclusions： Altitude of original living place, labor intensity are some of factors that impact the pulmonary-artery pressure of the people who exposure to a hypoxic environment. The pulmonary- artery pressure of person without strenuously physical work experience was more sensitive to hypoxic surroundings than that of labor workers. It was not always the fact at an extreme altitude that the moderate altitude mountaineers were superior to other migrants from a lower altitude or plain. The higher PH was found in the groups of the moderate altitude mountaineers and labor workers. It is unlikely certain that one with PH would surfer from HAPE.     

Therapeutic applications of bone marrow-derived stem cells in liver transplantation for end-stage liver diseases

Today, liver transplantation (LT) is the only established treatment for end-stage liver diseases. The de- velopment of LT, including OLT, cadaveric LT, split LT, living donor LT (LDLT), brings hopes to patients with these diseases. However, increasing donor shortage, rejection and life-long immunosuppression with its side effects are the major limitations of this therapy strategy. Bone marrow-derived stem cells (BMDSCs) are capable of differentiating into hepatocyte-like cells and contribute to liver injury repair. The microenvironment of liver injury caused by rejection, ischemia/reperfusion, loss of liver mass, recurrence of HCV and "small-for-size syndrome" after LT can attract a variety of bone marrow-derived stem cell population to the peripheral circulation and then migration to the injury liver to promote the hepatic function restoration. Additionally, BMDSCs can also take part in the functional regeneration of living donor liver after LDLT. This participation in liver regeneration may be associated to the interac- tion between SDF-1and its receptor CXCR4, involving HGF, IL-8, MMP9, and VEGF/VEGFR-2. BMDSC with its bio-characteristics could maintain the allograft tolerance from different angles and in different ways. In conclusion, BMDSCs transplantation, as a new assistant therapeutic method for LT, will ex- pand the space of LT, and provide more survival opportunities for the patients suffering liver diseases in the future.     

我国烟草业的几大发展战略研究进展

为了搞清楚我国烟草业的发展趋势,本文总结分析了目前比较有代表性的几个观点,得出结论:我国烟草由于受经营特殊性的制约,经营机制、体制都不完善,与国外烟草企业相比还存在比较大的差距;但是,整个行业的发展要求我国烟草走国际化、多元化的发展之路。因此,我们必须加强烟草业的体制改革,加强我国烟草品牌的品牌建设,加大烟草业人才开发建设力度,加强烟草行业科研,与国际烟草企业展开竞争。     

四川红层分布区地下水水化学若干问题探讨——以自贡市为例

利用钻孔试验分析了自贡红层分布区地下水水化学的水平及垂直分布特征,探讨了该区地下水的水化学特征及形成原因,进而探讨红层水资源开采等引起的咸淡水混合、水质变化等相关环境问题.     

核磁共振跟踪反应法研究5—O—乙酰基—2.3-双脱氧-D.L-呋喃戊糖基氯的合成

以乙酸四氢呋喃甲酯为原料,通过自由基氯化反应,合成双脱氧核苷类抗艾滋病药物的重要中间体化合物5—0—乙酰基—2.3—双脱氧—D.L—吹喃戊糖基氯.对于此种不稳定的中间体化合物,用~1HNMR跟踪监测反应物的方法,研究了改变反应时间、反应温度和反应物摩尔比对反应产物的影响,获得了最佳的反应条件,使其收率从10％提高到50％左右.     

气囊式蓄能器在煤矿采掘机械上应用的研究

本文探讨了气囊式蓄能器的工作原理和特性.并就蓄能器在煤矿采掘机械上的应用作了研究和探讨     

环氧乙烷四氢呋喃共聚醚[P(E-CO-T)]的研制

研究了环氧乙烷与四氢呋喃的共聚.使用BF_3络合物为催化剂,1,4-丁二醇为共催化剂.找到了溶液聚合和本体聚合适宜的工艺条件.在此条件下,环齐聚物的生成量为8％左右.找到了方便易行的纯化方法,通过纯化可把聚醚的环齐聚物含量降到1％以下,有效地提高了产品的质量。     

Mn_2O_3超微粒子的制备及其光学非线性

本文合成了表面修饰的Mn2O3，超微粒子（UFP）有机溶胶，并采用简并的四波混频（DFWM）手段研究了Mn2O3有机溶胶的三阶非线性光学特性，得到了较大的非线性极化率X3．最后讨论了Mn2O3超微粒子的三阶非线性产生机制．     

试论大学生卫生保健工作的信息管理

从系统论的观点来看，学生的卫生保健工作可作为教育系统的一个子系统。本文利用系统、信息庥和控制论的方法，首先试图分析该子系统的功能和各种相互依赖作用的关系，然后提出建立学生卫生保健工作信息管理的初步方案，高等教育的总目标就是培养德、智、体全面发展的高级人才，当然卫生保健工作的优化目标必须从属于该总目标。