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392.
以金霉素产生菌H-502作为出发菌株,采用紫外线加氯化锂作为复合诱变剂,通过生物技术手段获得了F-303变株。投产结果表明,该复株具有孢子萌发率高,发酵周期短,发酵单位高和放罐体积大的特点,发酵指数超过国际先进水平。 相似文献
393.
本文分析了本世纪八十年代金衢盆地的气候变化趋势。与前三个年代(五十、六十、七十年代)比较,八十年代具有变冷,少光,洪涝灾害频繁的趋势特征。同时,春季“三寒”(倒春寒、种田寒、5月寒),晚春初夏异常高温危害,夏凉,冬暖等异常现象突出。着重分析了气候变化及灾害演变对农林环境的不利影响,讨论了九十年代气候变异趋势及其对策。 相似文献
394.
资本市场中的头羊-从羊模型 总被引:8,自引:1,他引:7
针对目前中国证券市场中普遍存在着个人投资者对机构投资者的羊群行为这一特殊现象 ,建立了一个头羊 -从羊模型 .通过一定的参数假设和计算 ,定量地指出这种羊群行为增加了资产价格的波动 ,并且在大多数情况下头羊的收益大于从羊的收益 .但是随着头羊数量的增加和头羊收到的信息中的噪声增加 ,头羊 -从羊的收益之差减少 .最后从模型结论引申出稳定市场、改善市场结构、增加信息效率的建议. 相似文献
395.
本文描述了永磁非对称轴向二极场的结构和形态,这种磁场用于替代同轴线圈提供微波ECR等离子体CVD系统所需的磁场;简要分析了磁场对等离子体特性的影响。 相似文献
396.
介绍一种新型大功率氧化物导电陶瓷.该陶瓷是以六角密堆(HCP)结构的ZnO为主要原料,添加少量杂质,采用电子陶瓷工艺研制而成.研究了陶瓷材料的差热分析(DTA)及扫描电子显微结构.测量了瓷体的电阻率. 相似文献
397.
采用有限元方法分析了激光清洗过程中基片表面的温度分布,研究了激光清洗过程中清洗阈值和损伤阈值存在的原因,推导出使用波长为308nm,脉宽为28ns的准分子激光清洗硅片表面油脂的清洗阈值和损伤阈值,并进行了实验验证,其理论清洗阈值与实验结果是符合的 相似文献
398.
What’s new in the renin-angiotensin system? 总被引:6,自引:0,他引:6
Chai SY Fernando R Peck G Ye SY Mendelsohn FA Jenkins TA Albiston AL 《Cellular and molecular life sciences : CMLS》2004,61(21):2728-2737
The angiotensin AT(4) receptor was originally defined as the specific, high-affinity binding site for the hexapeptide angiotensin IV (Ang IV). Subsequently, the peptide LVV-hemorphin 7 was also demonstrated to be a bioactive ligand of the AT(4) receptor. Central administration of Ang IV, its analogues or LVV-hemorphin 7 markedly enhance learning and memory in normal rodents and reverse memory deficits observed in animal models of amnesia. The AT(4) receptor has a broad distribution and is found in a range of tissues, including the adrenal gland, kidney, lung and heart. In the kidney Ang IV increases renal cortical blood flow and decreases Na(+) transport in isolated renal proximal tubules. The AT(4) receptor has recently been identified as the transmembrane enzyme, insulin-regulated membrane aminopeptidase (IRAP). IRAP is a type II integral membrane spanning protein belonging to the M1 family of aminopeptidases and is predominantly found in GLUT4 vesicles in insulin-responsive cells. Three hypotheses for the memory-potentiating effects of the AT(4) receptor/IRAP ligands, Ang IV and LVV-hemorphin 7, are proposed: (i) acting as potent inhibitors of IRAP, they may prolong the action of endogenous promnestic peptides; (ii) they may modulate glucose uptake by modulating trafficking of GLUT4; (iii) IRAP may act as a receptor, transducing the signal initiated by ligand binding to its C-terminal domain to the intracellular domain that interacts with several cytoplasmic proteins. 相似文献
399.
Telomere length in humans is partly controlled by a feedback mechanism in which telomere elongation by telomerase is limited by the accumulation of the TRF1 complex at chromosome ends. TRF1 itself can be inhibited by the poly(ADP-ribose) polymerase (PARP) activity of its interacting partner tankyrase 1, which abolishes its DNA binding activity in vitro and removes the TRF1 complex from telomeres in vivo. Here we report that the inhibition of TRF1 by tankyrase is in turn controlled by a second TRF1-interacting factor, TIN2 (ref. 6). Partial knockdown of TIN2 by small hairpin RNA in a telomerase-positive cell line resulted in telomere elongation, which is typical of reduced TRF1 function. Transient inhibition of TIN2 with small interfering RNA led to diminished telomeric TRF1 signals. This effect could be reversed with the PARP inhibitor 3-aminobenzamide and did not occur in cells overexpressing a PARP-dead mutant of tankyrase 1. TIN2 formed a ternary complex with TRF1 and tankyrase 1 and stabilized their interaction, an effect also observed with the PARP-dead mutant of tankyrase 1. In vitro, TIN2 protected TRF1 from poly(ADP-ribosyl)ation by tankyrase 1 without affecting tankyrase 1 automodification. These data identify TIN2 as a PARP modulator in the TRF1 complex and can explain how TIN2 contributes to the regulation of telomere length. 相似文献
400.
End-to-end TCP (transmission control protocol) congestion control can cause unfairness among multiple TCP connections with different RTT (Round Trip Time). The throughput of TCP connection is inversely proportional to its RTT. To resolve this problem, researchers have proposed many methods. The existing proposals for RTT-aware conditioner work well when congestion level is low. However, they over-protect long RTT flows and starve short RTT flows when congestion level is high. Due to this reason, an improved method based on adaptive thought is proposed. According to the congestion level of networks, the mechanism can adaptively adjust the degree of the protection to long RTT flows. Extensive simulation experiments showed that the proposed mechanism can guarantee the bandwidth fairness of TCP flows effectively and outperforms the existing methods. 相似文献