Finding finer functions for partially characterized proteins by protein-protein interaction networks

Based on high-throughput data, numerous algorithms have been designed to find functions of novel proteins. However, the effectiveness of such algorithms is currently limited by some fundamental factors, including (1) the low a-priori probability of novel proteins participating in a detailed function; (2) the huge false data present in high-throughput datasets; (3) the incomplete data coverage of functional classes; (4) the abundant but heterogeneous negative samples for training the algorithms; and (5) the lack of detailed functional knowledge for training algorithms. Here, for partially characterized proteins, we suggest an approach to finding their finer functions based on protein interaction sub-networks or gene expression patterns, defined in function-specific subspaces. The proposed approach can lessen the above-mentioned problems by properly defining the prediction range and functionally filtering the noisy data, and thus can efficiently find proteins’ novel functions. For thousands of yeast and human proteins partially characterized, it is able to reliably find their finer functions (e.g., the translational functions) with more than 90% precision. The predicted finer functions are highly valuable both for guiding the follow-up wet-lab validation and for providing the necessary data for training algorithms to learn other proteins.     

透湿过程中织物的润湿和散湿作用

采用蒸发和吸湿法测量多种织物的透湿速率，并且仔细研究用蒸发法时，织物润湿程度在透湿过程中的变化，发现织物在透湿过程中的润湿和放湿，以及织物的表面性状是影响其放湿速率的非常重要的因素。     

电磁相分离法制备自生表层复合材料

采用电磁相分离法制备出以初生富铁相（AlSiFeMn复杂金属间化合物）为增强相，表层硬度为HB62．25，基体硬度为HB59．00的Al-11.70%Si-1.20?-1.50%Mn合金自生表层复合材料，增强相的显微硬度为HV 842。87，大小为20－80μm，该表层复合材料同基体材料相比，耐磨性提高了57．41％，所用方法工艺过程简单，成本低，为解决材料在服役环境中不同部位，不同性能的问题提供了新途径。     

并行仿真计算的任务划分问题研究

本文首先分析总结了并行仿真计算任务的三类任务划分方法：算术运算级划分、程序方程级划分和状态变量级划分，然后重点讨论状态变量级的最优划分问题。文中针对同构型的多处理机系统和多计算机系统，分别建立了仿真计算的性能模型，并求出了系统的最优划分粒度。     

Fe_3Al的抗高温氧化和耐热腐蚀性能

在７００℃与８５０℃的高温下，Ｆｅ＿３Ａｌ金属间化合物表面形成了Ａｌ＿２Ｏ＿３保护膜，使其抗氧化性能远优于不妨钢，２％Ｃｒ（原子百分比）加入Ｆｅ＿３Ａｌ会导致氧化过程初期氧化速率的增高，在熔融的硫酸盐和高压锅炉的烟气中，Ｆｅ＿３Ａｌ的耐热腐蚀性能优于高温合金ＧＨ１３２．     

输出/输入比值优势与DEA有效

进一步讨论了多目标规划模型 ( vp)中的 Pareto有效与 DEA有效的关系 ,得到两个重要结论 ,藉此无须求解 DEA模型就能判断某些 Pareto有效 DMU的 DEA有效性。     

现代意义下作战模型的研究

本文阐述了现代战争的特点，构造了现代意义下的作战模型，通过求解与分析，指明信息在现代战争中的重要作用和对未来战争的指导意义。     

Abnormal dielectric characteristics of PMN-32%PT single crystal under dc bias

It has been reported that the single crystal of relaxor ferroelectrics (1-x)Pb(Mg1/3Nb2/3)O3-xPbTiO3 (PMN-xPT) with the compositions near the morphotropic phase boundary (MPB, 0.28相似文献   

论思辨与创造想象互补的科学创造之基本思维形式--兼评几种流行的成对思维形式互补的方法论模式

思辨援引高层观念作为创造思维的出发点和孕育新思想的观念母体，并紧紧依靠逻辑的拐杖；创造想象为观念(高层观念、创造观念、创生观念)与经验事实的结合提供形象推理模型，二者互补构成科学创造思维的实质程序和基本思维形式。左脑思维与右脑思维互补、收敛思维与发散思维互补、纵向思维与横向思维互补等等不足以成为创造的基本思维形式，而只能算是某种思维方法或创造技法，原因在于它们是彼此分离的历时互补，在于它们不关注创造内容之运动。     

一些特殊树的对偶带宽

图G的对偶带宽是指图G中相邻两点最小标号差的最大值。确定了一些特殊树的对偶带宽，主要结果如下：(1)如果树T有n个顶点，并且其最大度△(T)不小于[n/2]，那么树T的对偶带宽等于n一△(T)的充要条件为T是双层星且其内星的中心为最大度顶点；(2)完全二叉树T2,k的对偶带宽等于2^k-1；(3)等高单毛虫树Pm,n的对偶带宽为[mn/2]。