鄂东大别山生物多样性研究

对鄂东大别山区的生物多样性进行了研究.目前已知该区有维管植物195科663属1 461种,占湖北省总种数的24.27%和全国总种数的5.25%,属国家特有、珍稀濒危或重点保护的植物有34种,有苔藓植物30科64属143种.已知该区有陆生脊椎动物26目65科208种,占湖北省总种数的31.04%和全国总种数的8.09%,其中有27种国家重点保护野生动物和61种湖北省级重点保护动物.该区自然植被类型有10个植被型,52个群系.该区不仅动植物区系成分多样性复杂,而且经济类型多样.     

虚拟极化增强雷达目标信号接收的原理和实现

利用双正交偶极子接收雷达回波信号,在天线的正交双通道中进行虚拟极化处理来增强信号、抑制杂波是改善目标信噪比的有效方法.文中介绍了虚拟接收变极化的原理,并运用虚拟极化实现了目标极化增强和杂波抑制,通过matlab仿真得到了直观的信噪比增强效果.     

WDR34 is a novel TAK1-associated suppressor of the IL-1R/TLR3/TLR4-induced NF-κB activation pathway

Toll-like receptors (TLRs) act as sensors of microbial components and elicit innate immune responses. All TLR signaling pathways activate the nuclear factor-kappaB (NF-κB), which controls the expression of inflammatory cytokine genes. Transforming growth factor-β-activated kinase 1 (TAK1) is a serine/threonine protein kinase that is critically involved in the activation of NF-κB by tumor necrosis factor (TNFα), interleukin-1β (IL-1β) and TLR ligands. In this study, we identified a novel protein, WD40 domain repeat protein 34 (WDR34) as a TAK1-interacting protein in yeast two-hybrid screens. WDR34 interacted with TAK1, TAK1-binding protein 2 (TAB2), TAK1-binding protein 3 (TAB3) and tumor necrosis factor receptor-associated factor 6 (TRAF6) in overexpression and under physiological conditions. Overexpression of WDR34 inhibited IL-1β-, polyI:C- and lipopolysaccharide (LPS)-induced but not TNFα-induced NF-κB activation, whereas knockdown of WDR34 by a RNA-interference construct potentiated NF-κB activation by these ligands. Our findings suggest that WDR34 is a TAK1-associated inhibitor of the IL-1R/TLR3/TLR4-induced NF-κB activation pathway. D. Gao and R. Wang contributed equally to this work.     

Molecular mechanisms of BK channel activation

Large conductance, Ca²⁺-activated potassium (BK) channels are widely expressed throughout the animal kingdom and play important roles in many physiological processes, such as muscle contraction, neural transmission and hearing. These physiological roles derive from the ability of BK channels to be synergistically activated by membrane voltage, intracellular Ca²⁺ and other ligands. Similar to voltage-gated K⁺ channels, BK channels possess a pore-gate domain (S5–S6 transmembrane segments) and a voltage-sensor domain (S1–S4). In addition, BK channels contain a large cytoplasmic C-terminal domain that serves as the primary ligand sensor. The voltage sensor and the ligand sensor allosterically control K⁺ flux through the pore-gate domain in response to various stimuli, thereby linking cellular metabolism and membrane excitability. This review summarizes the current understanding of these structural domains and their mutual interactions in voltage-, Ca²⁺ - and Mg²⁺ -dependent activation of the channel. Received 25 September 2008; received after revision 23 October 2008; accepted 24 October 2008     

基于Kramers-Kronig关系的油纸绝缘直流电导计算方法

针对区分介电谱中电导和极化过程的方法较为缺乏,等效模型中表征电导的参数唯一性计算方法不足的问题.以油纸绝缘介质的电导过程为研究对象,在实验条件下制备不同水分含量的油纸绝缘样品,并测量频域响应谱线.基于Kramers-Kronig关系对测量复极化率实部谱线进行数值积分,获得弛豫损耗谱线,进而得到电导损耗谱线;并使用最小二...     

发动机支架安装凸台的断裂故障诊断分析

针对发动机发电机支架安装凸台及连接螺栓常出现的断裂失效问题,提出一种仿真分析与实验结合的诊断方法.首先建立了包含发电机和空压机模型的支架有限元模型,并进行了约束模态分析,进而针对缸体局部和电机支架进行了螺栓预紧应力分析.最后,对发电机和空压机进行了动平衡测试.仿真与试验结果表明:发动机运行期间,连接区域松脱可能是造成失效的重要原因.采用该诊断方法解决了失效问题.     

冰箱回热毛细管计算模型

在分析现有的冰箱毛细管主要计算模型的基础上,针对冰箱毛细管实际应用情况,建立了冰箱回热毛细管六段流阻模型.该模型充分考虑了回气管与毛细管回热长度以及毛细管进出口截面突变的影响,并对冰箱回热毛细管在三种不同工况下的性能进行了模拟,研究了冷凝温度、蒸发温度、以及毛细管相对位置对毛细管工作性能的影响,结果显示冷凝温度对回热毛细管内的制冷剂流动特性影响最大.     

光学编码成像术中光源稳定性研究

针对光学编码成像的光源强度随时间波动对编码成像结果的影响,研究了编码机制对光源光强变化响应的表现,发现了阿达玛变换光学系统对光源强度波动的特异敏感性规律:像元强度改变量与光源光强波动量成比例;一个编码周期内光源光强的多次波动导致像元强度改变量按次累加但并不导致发散;各次源强度波动对像场强度改变量的分布具有循环性.采用数值模拟方法计算了与1×7阵列像场对应的7阶S矩阵编码成像,结果表明光源光强随时间的变化对编码成像质量有严重影响.指出了在编码成像系统中所用的光源的不稳定性应该受到的限制.     

DEM最优线性生成技术——MADEM

讨论了DEM生成方法和高精度、高保真问题.指出评价生成方法的误差必须顾及内插模型的截断误差,并把它作为主要部分;给出了新型的地图代数DEM生成方法--MADEM(map algebra DEM),它是定义在最速下降线水平投影上的线性插值方法,通过赋值点线间的加权Voronoi的递归内插过程实现.它在同样条件下,具有远高于Delaunay构网下三角形上的线性插值方法精度,并具有高保真特性.分析和实例比较表明它是目前DEM最优的线性内插方法.     

Hadamard变换光学编码探测中的定位精度研究

针对Hadamard光学成像的编码定位精度波动对编码成像结果的影响,研究了编码机制对定位偏差响应的表现,发现了阿达玛变换光学系统对定位精度波动的敏感性规律:像元强度改变量与定位偏差量成比例;一个编码周期内定位偏差的多次波动导致像元强度改变量按次累加;各次波动对像场强度改变量分布具有循环性.采用63阶码板实验以及数值模拟方法计算63阶、255阶和511阶S矩阵编码成像,结果表明定位精度的变化对编码成像质量有重要影响.给出了在编码成像中所应用的编码矩阵折叠形式与定位精度的相关关系,为编码成像系统的精度设计给出了理论基础.