基于动态流量矩阵的网络链路权值调整方法

对基于动态流量矩阵的流量均衡问题进行建模,以最小化最大链路利用率为目标分别建立了期望值模型和机会约束模型,并且采用基于流分析的方法计算链路的权值增量,使部分流不再经过利用率最大的链路.仿真实验结果表明:无论是针对期望值模型还是机会约束模型,在已知动态流量矩阵统计特性的情况下,基于流分析的链路权值调整方法都能在只改变利用率最大的链路的权值时,依然保证网络失效后流量基本均衡.     

Act in contravention: a non-planar coupled electrode design utilizing "tip effect" for ultra-high areal capacity,long cycle life zinc-based batteries

Aqueous zinc-based batteries (ZBBs) have great potential as commercial energy storage devices.However,the poor cycling stability of zinc anode under high areal ...     

桉树叶中黄酮类化合物的提取工艺研究

讨论了影响黄酮类化合物提取率的主要因素,并确定了较好的提取工艺,结果表明:以φ=65%的乙醇、粒度为30目的桉树叶粉按m料∶V乙醇=1∶12的比例,浸泡24 h,然后在70℃下提取2 h,可得到质量含量为3.41%的总黄酮.     

闽南地区农村住宅安全性现状及防灾建议

在对厦门市海沧区近9 000栋农村住宅的安全性和耐久性现状普查基础上,分析该地区农村住宅的结构类型分布特点和不同类型房屋的安全性等级分布.针对该地区农村住宅存在的安全性和耐久性问题,提出该地区农村住宅防御自然灾害,特别是防御地震灾害的相关建议.     

Differentiated cells are more efficient than adult stem cells for cloning by somatic cell nuclear transfer

Since the creation of Dolly via somatic cell nuclear transfer (SCNT), more than a dozen species of mammals have been cloned using this technology. One hypothesis for the limited success of cloning via SCNT (1%-5%) is that the clones are likely to be derived from adult stem cells. Support for this hypothesis comes from the findings that the reproductive cloning efficiency for embryonic stem cells is five to ten times higher than that for somatic cells as donors and that cloned pups cannot be produced directly from cloned embryos derived from differentiated B and T cells or neuronal cells. The question remains as to whether SCNT-derived animal clones can be derived from truly differentiated somatic cells. We tested this hypothesis with mouse hematopoietic cells at different differentiation stages: hematopoietic stem cells, progenitor cells and granulocytes. We found that cloning efficiency increases over the differentiation hierarchy, and terminally differentiated postmitotic granulocytes yield cloned pups with the greatest cloning efficiency.     

基于城市公交探测车数据的分析和处理方法

将智能公交系统的智能车辆作为交通移动采集的一种方式,详细分析了智能公交系统的数据流程及公交车作为交通探测车的可行性,随后本文根据公交探测车GPS数据的时域图和“时间—距离”图分析了公交车的运行状态,并详细推导了基于公交探测车数据的行程时间估计算法。     

多元合金的电子、原子层次理论计算及应用

本文是在电子、原子层次上进行多元合金设计的一个初步探索。利用量子化学从头计算方法或者第一性原理赝势平面波方法,构建了多元合金的原子间相互作用势。研究表明,由原子间相互作用势计算确定合适的基体成分,选择尝试的合金总成分,通过经验公式计算碳化物体积分数,以相平衡热力学计算取得与合适的相结构对应的合金总成分．由试验检验设计的合理性。这样的一种思路是可行的。     

The Pristionchus pacificus genome provides a unique perspective on nematode lifestyle and parasitism

Here we present a draft genome sequence of the nematode Pristionchus pacificus, a species that is associated with beetles and is used as a model system in evolutionary biology. With 169 Mb and 23,500 predicted protein-coding genes, the P. pacificus genome is larger than those of Caenorhabditis elegans and the human parasite Brugia malayi. Compared to C. elegans, the P. pacificus genome has more genes encoding cytochrome P450 enzymes, glucosyltransferases, sulfotransferases and ABC transporters, many of which were experimentally validated. The P. pacificus genome contains genes encoding cellulase and diapausin, and cellulase activity is found in P. pacificus secretions, indicating that cellulases can be found in nematodes beyond plant parasites. The relatively higher number of detoxification and degradation enzymes in P. pacificus is consistent with its necromenic lifestyle and might represent a preadaptation for parasitism. Thus, comparative genomics analysis of three ecologically distinct nematodes offers a unique opportunity to investigate the association between genome structure and lifestyle.     

A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration

Epithelial organs, including the lung, are known to possess regenerative abilities through activation of endogenous stem cell populations, but the molecular pathways regulating stem cell expansion and regeneration are not well understood. Here we show that Gata6 regulates the temporal appearance and number of bronchioalveolar stem cells (BASCs) in the lung, its absence in Gata6-null lung epithelium leading to the precocious appearance of BASCs and concurrent loss in epithelial differentiation. This expansion of BASCs was the result of a pronounced increase in canonical Wnt signaling in lung epithelium upon loss of Gata6. Expression of the noncanonical Wnt receptor Fzd2 was downregulated in Gata6 mutants and increased Fzd2 or decreased beta-catenin expression rescued, in part, the lung epithelial defects in Gata6 mutants. During lung epithelial regeneration, canonical Wnt signaling was activated in the niche containing BASCs and forced activation of Wnt signaling led to a large increase in BASC numbers. Moreover, Gata6 was required for proper lung epithelial regeneration, and postnatal loss of Gata6 led to increased BASC expansion and decreased differentiation. Together, these data demonstrate that Gata6-regulated Wnt signaling controls the balance between progenitor expansion and epithelial differentiation required for both lung development and regeneration.     

基于加权最小二乘拟蒙特卡罗的美式期权定价

美式期权定价具有后向迭代搜索特征, 在最小二乘拟蒙特卡罗模拟(least-squares quasi-Monte Carlo, LSM)方法的基础上, 本文通过随机Faure序列以及对偶变数法增加抽样数目, 达到减小模拟方差的目的,用其计算标的资产价格, 然后用加权最小二乘法进行回归, 得到了加权最小二乘拟蒙特卡罗(weighted least-squares quasi-Monte Carlo, WLSQM)方法. 从期权价值、标准差、运行时间几个方面比较方法的优劣, 得出WLSQM 方法比LSM 方法估计效果更优的结果, 验证了WLSQM方法在美式期权定价上的有效性.