CFRP加固钢绞线-钢筋混凝土剪力墙性能

为了探讨采用碳纤维布加固塑性铰区对钢绞线-钢筋混凝土剪力墙抗震性能的影响，制作了2个钢绞线-钢筋混凝土剪力墙试件，通过拟静力加载试验，研究了碳纤维布加固塑性铰区的钢绞线-钢筋混凝土剪力墙的抗震性能及其可恢复性能。研究结果表明：采用碳纤维布加固剪力墙塑性铰区可以有效提高钢绞线-剪力墙的承载能力和侧向变形能力，而且在高轴压比作用下对提高其承载能力效果更好，滞回环更加饱满，耗能能力有一定的提高，但对其残余变形没有明显影响。     

Reliability Analysis Based on a Nonlinear Fatigue Damage Accumulation Model

A modified nonlinear fatigue damage accumulation model based on the Manson-Halford theory was presented,and the new model was developed for fatigue life prediction under constant and variable amplitude loading, which took the effects of the load interactions and the phenomenon of material＇s strength degradation into account. The experimental data of the 30 Cr Mn Si A and the LY-12 cz from literature were used to verify the proposed model. And from the good agreement between the experimental data and predicted results,we can see it clear that the proposed method can be applied to predicting fatigue life under different loadings.     

GLP-1R agonists therapy for type 2 diabetes

Glucagon-like peptide-1 receptor （GLP-1R） agonists are widely used for treating type 2 diabetes mellitus （T2DM） be- cause of their glucose-lowering and weight-losing effects, and low risk of hypoglycemia. Hence, there is considerable interest in understanding the mechanism underlying the beneficial effects of GLP-I and developing stable and effective GLP-1R agonists. Here, we summarize the presently known mechanism of GLP-I actions, which are mainly through regulating cAMP-PKA signaling pathway; the latest developments in novel clinical GLP-1R agonists are also introduced, which are characterized with multiple properties, such as extended half-life, reduced side-effects, lower production costs and more convenient drug dosing mode. The potential risk of GLP-I-based therapeutics, an often-ignored fact, is also discussed.     

平顺移动模式下考虑加工时间与调整时间可分离的多目标流水车间批量调度

对平行顺序移动模式下考虑加工时间与调整时间可分离的多目标流水车间批量调度问题展开研究.构建以加工制造设备总停机次数、批量工件生产周期以及搬运批量工件的总次数为决策目标的基于分层序列法的多目标决策模型,利用该模型可确定批量工件的最优加工排序方案.建立平行顺序移动模式的加工与调整时间模型,该模型是求解生产周期的基础,也是为批量工件的最优调度方案制定生产作业计划的依据.提出并设计平行顺序移动模式下考虑加工时间与调整时间可分离的禁忌搜索算法对问题进行求解.研究结果表明:本研究可为平顺移动模式下考虑加工时间与调整时间可分离的批量生产流水车间选出批量工件的最优调度方案,同时可为批量工件的加工和加工制造设备的调整制定精确的生产作业计划.     

影响螺纹副轴向力分布均匀性的关键因素分析

通过对螺纹连接结构承载分布问题的理论分析与数值模拟,探索影响螺纹副轴向力分布均匀性的关键因素.首先对螺纹副轴向承载分布进行理论分析,提出依据螺纹副截面上单位长度荷载F与螺纹牙相对变形u的关系曲线确定轴向力分布的解析方法.理论分析表明,当F-u关系曲线呈屈服形状时,螺纹副轴向承载力分布更加均匀.其次,对施必牢螺纹副进行分析,发现其F-u关系曲线呈现出屈服特征;从牙型设计、材料塑性和螺纹错动三方面进行分析,阐明施必牢螺纹副承载分布均匀性好的力学机制;最后,详细分析了螺纹副径向尺寸系数、摩擦因数和材料特性等因素对螺纹上轴向力分布的影响规律.     

Risk reduction in a project portfolio

The positive impacts of managing projects as a portfolio are quantified by comparing the value of the integrated risk of a project portfolio and the aggregation of single project risks implemented separately. Firstly, the integrated risk is defined by proposing risky events based on set theory. Secondly, as projects interact with each other in a project portfolio, the integrated risk is evaluated by using a Bayesian network structure learning algorithm to construct an interdependent network of risks. Finally, the integrated risk of a practical case is assessed using this method, and the results show that the proposed method is an effective tool for calculating the extent of risk reduction of implementing a project portfolio and identifying the most risky project, so as to assist companies in making comprehensive decisions in the phase of portfolio selection and portfolio controlling.     

三氯乙酸催化合成β-烯胺酮类化合物

在三氯乙酸催化剂的作用下,以乙醇为溶剂,将芳香胺类化合物和β-二酮一锅反应合成β-烯胺酮类化合物.此法高效、安全,操作便捷,且产率高.     

“美丽中国”视阈下的大学生“美丽人生”思想政治教育内容及路径探索

党的十八大提出了建设“美丽中国”新理念。“美丽中国”的建设离不开人的美丽，“美丽人生”是“美丽中国”的人文基础，而“美丽人生”离不开大学生这个特殊群体的人生的美丽，“美丽人生”的获得离不开大学生思想政治教育。为此，高校要强化主导制、导师制、人文制和协同制，让“美丽中国”因为有大学生人生的美丽而蕴含人文的光彩。     

基于办学特色的公安院校文献资源建设研究——以南京森林警察学院为例

阐述了南京森林警察学院的办学特色和文献资源建设现状,探讨了公安院校文献资源建设目前面临的问题,提出了基于特色办学的公安院校文献资源建设途径与措施。