Anti-nociceptive role of neuropeptide Y in the nucleus accumbens in rats with inflammation, an effect modulated by mu- and kappa-opioid receptors

Recent study in our laboratory showed that neuropeptide Y (NPY) plays an antinociceptive role in the nucleus accumbens (NAc) in intact rats. The present study was performed to further investigate the effect of NPY in nociceptive modulation in the NAc of rats with inflammation, and the possible interaction between NPY and the opioid systems. Experimental inflammation was induced by subcutaneous injection of carrageenan into the left hindpaw of rats. Intra-NAc administration of NPY induced a dose-dependent increase of hindpaw withdrawal latencies (HWLs) to thermal and mechanical stimulations in rats with inflammation. The anti-nociceptive effect of NPY was significantly blocked by subsequent intra-NAc injection of the Y1 receptor antagonist NPY28-36, suggesting an involvement of Y1 receptor in the NPY-induced anti-nociception. Furthermore, intra-NAc administration of the opioid antagonist naloxone significantly antagonized the increased HWLs induced by preceding intra-NAc injection of NPY, suggesting an involvement of the endogenous opioid system in the NPY-induced anti-nociception in the NAc during inflammation. Moreover, the NPY-induced anti-nociception was attenuated by following intra-NAc injection of the μ-opioid antagonist β-funaltrexamine (β-FNA), and κ-opioid antagonist nor-binaltorphimine (nor-BNI), but not by δ-opioid antagonist naltrindole, indicating that μ- and κ-opioid receptors, not δ-opioid receptor, are involved in the NPY-induced anti-nociception in the NAc in rats with inflammation.     

Numerical simulation of the sensitivity of the Pacific subtropical-tropical meridional cell to global warming

Sensitivity of the Pacific subtropical-tropical meridional cell to global warming is examined by using a global ocean-atmosphere coupled model developed at LASG/IAP. Results indicate that associated with the increasing of atmospheric carbon dioxide, the most prominent signals of global warming locate at high latitudes, and the change of middle and low latitudes, in particular the surface wind, is relatively weak, which leads to a weak response of the Pacific subtropical-tropical meridional cell. At the time of atmospheric carbon dioxide doubling, the change of the meridional cell strength is smaller than the amplitude of natural variability.     

款冬花色素的提取与稳定性研究

研究了款冬花色素的热稳定性、氧化还原稳定性和pH值稳定性，并对常用的几种食品添加剂对款冬花色素的稳定性进行了探讨，结果表明：款冬花色素易溶于丙酮。属于脂溶性色素；在ph=3～9时，款冬花色素的稳定性较好，氧化还原剂及食品添加剂对其稳定性影响不大，Fe^3＋金属离子对其影响显著，Na^＋有增色作用，水浴温度在60℃以下色素的热稳定性较好。     

一种基于Cross-Product与HashTree的IP分类算法

在Cross-Product算法的基础上，结合哈希树（HashTree）数据结构，综合二者的优点，提出了一种新的IP分类算法CPHTIT（Cross-Product and HashTree with index table）。仿真结果表明CPHTIT在时间和空间上都达到了高速IP分类的要求，与现有经典算法Grid of Tries和Modular比较，其综合性能有所改进。     

基于MSP430单片机的以太网供电设备的软件设计

网络供电是EPA的关键技术之一，简要介绍了IEEE8．02．3af标准，系统分析了以太网供电设备的功能需求和总体设计，选用MSP430F148单片机和TPS2383A以太网供电电源管理器，基于I^2C-BUS通信规范，开发了符合IEEE802．3af标准的以太网供电设备，着重论述了该以太网供电设备的软件实现过程，最后给出了该供电设备在EPA系统中的应用实例，具有良好的使用效果。     

成语"骄奢淫逸"的语源及其形成过程

成语"骄奢淫逸"源于《左传》,经历了单音词单独运用、近义词两两连用阶段,最后四字连文定型为今成语,其词义古今也有所不同.     

轧制工艺对CSP线热轧汽车用高强钢板组织特征的影响

研究了薄板坯连铸连轧(CSP)工艺生产高强度汽车用大梁板的工艺控制参数与力学性能和显微组织间的关系.根据柔性工艺控制的指导思想,在珠钢电炉CSP流程下实现了生产不同级别高强度钢板的柔性轧制工艺.利用扫描电镜和透射电镜研究了其组织和强度差异产生的原因.研究表明,钢板最终组织为多边形铁素体和少量珠光体组成,平均铁索体晶粒尺寸约为3.7～5.6μm;当降低卷取温度,部分渗碳体已破碎成细小的碳化物粒子分布于铁素体基体上,钢板中有少量贝氏体出现.     

钎焊-热轧法制备高速公路不锈钢复合护栏

针对当前高速公路热镀锌护栏存在的主要问题,提出采用不锈钢/碳钢复合板作为新型高速公路护栏材料.研究了钎焊-热轧法制备不锈钢复合护栏的工艺,技术路线为通过炉中钎焊实现不锈钢/碳钢的初结合,对钎焊复合板进行热轧进一步提高结合强度.研究结果表明:采用自制的Ag质量分数为15%的钎料可以实现不锈钢/碳钢有效的钎焊结合,钎焊温度720~730℃,钎焊时间3~4 min是较理想的工艺条件.对钎焊复合板热轧可以显著提高不锈钢/钎料界面的结合强度,压下率低于30%时,轧后钎料层未出现断裂、分层.热轧后,不锈钢复合护栏剪切强度可达338.4 MPa.     

金翅中脑峡核的组织学研究

分析与讨论了峡核和视觉功能关系,为进一步研究峡核的功能提供形态学资料.制备冰冻切片,用美蓝染色和HE染色观察了鸣禽——金翅(Carduelis sinica)中脑峡核的位置、形态和细胞组成.结果表明:峡核中Imc和Ipc中的细胞存在明显的形态学差异;Imc中的细胞多梨形、椭圆形,胞体较大,平均为16~33μm,有多个树突分技;Ipc中细胞胞体相对较小,平均为10~20μm,有较少树突分枝,多为圆形胞体.     

一种基于过滤器的无线传感器网络复杂查询优化算法

无线传感器网络节点无法获得持久的能量供应,因此高效地利用有限的能量,尽可能多地延长节点工作时间,是无线传感器网络中的重要研究点.介绍了一种基于过滤器的无线传感器网络复杂查询优化算法FbUA.其基本思想是为每一个无线传感器网络节点设置一个过滤器.过滤器本质上是一个由样本值确定的取值区间.当节点采集到新数据时,根据本地的过滤规则决定是否向上提交.这样可以屏蔽某些无用通信,节省节点能量,延长其工作时间.FbUA可以完成Top-k,k-NN等复杂查询.模拟实验结果表明,在多数情况下,FbUA可以节约通信量50%~70%.