复方舒心胶囊中绿原酸在家兔胃肠吸收试验

对两组家兔的胃肠道分别进行在体提取液单向灌流，并定时收集胃肠灌流液，运用紫外分光光度法建立标准曲线，以绿原酸的浓度为指标测算吸收情况。结果表明，提取液中的绿原酸在家兔胃肠道部分均有明显吸收，且小肠段的吸收程度高于胃部。     

Spatial dependence model with feature difference

This paper presents a new spatial dependence model with an adjustment of feature difference. The model accounts for the spatial autocorrelation in both the outcome variables and residuals. The feature difference adjustment in the model helps to emphasize feature changes across neighboring units, while suppressing unobserved covariates that are present in the same neighborhood. The prediction at a given unit incorporates components that depend on the differences between the values of its main features and those of its neighboring units. In contrast to conventional spatial regression models, our model does not require a comprehensive list of global covariates necessary to estimate the outcome variable at the unit, as common macro-level covariates are differenced away in the regression analysis. Using the real estate market data in Hong Kong, we applied Gibbs sampling to determine the posterior distribution of each model parameter. The result of our empirical analysis confirms that the adjustment of feature difference with an inclusion of the spatial error autocorrelation produces better out-of-sample prediction performance than other conventional spatial dependence models. In addition, our empirical analysis can identify components with more significant contributions.     

半胱氨酸亚金铵的合成、理化性质及电镀金应用

以半胱氨酸为配体合成一种新型亚金配合物NH4Au(Cys)2,对该配合物进行元素分析、红外光谱、紫外光谱、热失重分析和导电性测量等理化性质研究;以该亚金配合物为金源开展相关的电镀金工艺探索,并通过四因素三水平的正交试验获得其最佳条件参数;采用扫描电子显微镜(SEM)和X线衍射(XRD)对镀金层的表面质量进行探讨。研究结果表明:该目标产物的分子式为NH4Au(Cys)2·2H2O,该配合物中以半胱氨酸的巯基和金配位为成健特征,在170℃以下热稳定性较好,该亚金配合物是一个典型的离子化合物。在电流密度为200~300 A/m2,p H为10.5~12.0,温度为35~45℃,金质量浓度为15~25 g/L的电镀工艺条件下,得到粒度为0.5~1.0μm的单质金,且主要沿着(111)面进行生长。     

白洋淀轮虫群落结构及富营养化评价

于2018年5月(春)、8月(夏)和10月(秋)对白洋淀26个采样点轮虫物种组成和群落结构进行了系统调查,测定了水温(WT)、溶解氧(DO)、pH值、水深(WD)、透明度(Tr)、总氮(TN)、总磷(TP)、叶绿素a(Chla)等环境因子,分析了轮虫群落参数与环境因子的关系,综合评价了白洋淀水体富营养化程度.共鉴定出轮虫21属61种,以耐污性种类为主,角突臂尾轮虫、萼花臂尾轮虫和小多肢轮虫为优势种.各采样点轮虫种数差异较大,最多为20种(聚龙淀),最少仅为6种(大麦淀).轮虫平均丰度和生物量呈现明显的季节变化,秋季最高(3 372 ind./L,0.90 mg/L),夏季其次(1 240 ind./L,0.88 mg/L),春季最低(210 ind./L,0.22 mg/L);轮虫最高丰度为6 930 ind./L(三角淀,秋季),最低仅为2 ind./L(平阳淀,夏季).Shannon-Wiener多样性指数(H')和Pielou均匀度指数(J)夏季最高(分别为2.30和0.86).经相关性分析发现,轮虫丰度与DO、WD、Chla、TP呈显著正相关,而与Tr显著负相关;轮虫种数与WD显著正相关,与WT显著负相关.与历史资料相比,白洋淀水质在一定程度有所好转,但仍处于富营养化状态.     

大思政教育背景下软件工程课程思政教学改革探索与实践

为更好地将专业教育与思政教育有机融合,充分发挥专业课程的育人功能,各学校积极开展课程思政教学改革试点工作,逐步形成"大思政"教育体系。以专业主干课程软件工程为例,在分析教学内容和目标基础上,从科学素养培养、创新意识强化、生活处事哲理灌输等方面阐述了该课程开展课程思政的着眼点,并分别从教学内容设计、教学方法改革和教学评价改进等方面详细分享了开展课程思政的经验和做法。实践表明,上述措施切实加强了学生科学素养、法治素养、民族自信和创新意识的培养,达到了课程思政教育的目的,取得了较为满意的效果。     

Processing and characterization of the microstructure and mechanical properties of Al6061–TiB2 composite

In the present research, aluminum metal matrix composites were processed by the stir casting technique. The effects of TiB2 rein-forcement particles, severe plastic deformation through accumulative roll bonding (ARB), and aging treatment on the microstructural charac-teristics and mechanical properties were also evaluated. Uniaxial tensile tests and microhardness measurements were conducted, and the micro-structural characteristics were investigated. Notably, the important problems associated with cast samples, including nonuniformity of the rein-forcement particles and high porosity content, were solved through the ARB process. At the initial stage, particle-free zones, as well as particle clusters, were observed on the microstructure of the composite. However, after the ARB process, fracturing phenomena occurred in brittle ceramic particles, followed by breaking down of the fragments into fine particles as the number of rolling cycles increased. Subsequently, com-posites with a uniform distribution of particles were produced. Moreover, the tensile strength and microhardness of the ARB-processed com-posites increased with the increase in the reinforcement mass fraction. However, their ductility exhibited a different trend. With post-deforma-tion aging treatment (T6), the mechanical properties of composites were improved because of the formation of fine Mg2Si precipitates.     

Research Articles¶Naturally occurring 2′-O-methylpurine nucleosides with hypotensive properties

2′-O-Methylinosine (1) has been isolated for the first time and shown to be an intrinsic hypotensive principle. Its probable in vivo precursor, 2′-O-methyladenosine (3), showed stronger and even orally potent hypotensive activity. Resistance of the methyladenosine (3) against adenosine deaminase is thought to contribute to its long-lasting activity. The effect of both nucleosides (1 and 3) was not accompanied with any significant change in heart rate, which is often observed with adenosine. Received 2 October 1997; accepted 28 October 1997     

高方盒末次拉深中角部壁间距的优化计算

本文从主同盒形件末次拉深的变形分析出发,建立数学模型,对末次拉深中角部壁间距δ进行了优化计算,对工艺设计具有指导意义。     

工艺条件对 BGA 焊点电性能的影响

研究不同的焊接温度及焊接时间对ＢＧＡ焊点电性能和疲劳特性的影响．测试了不同焊接条件和热处理下焊点的电阻及其与温度的关系,并比较了不同样品在热冲击前后的电性能．实验发现在２３０℃下保温３００ｓ,焊接的焊点具有良好的电性能和疲劳特性,且在ｌ００℃下热处理ｌ５ｍｉｎ后样品的电性能和疲劳特性都有较大提高．     

准噶尔盆地南缘油页岩特征及控矿条件

准噶尔盆地南缘油页岩资源储量巨大且发现已久,详细研究该区油页岩特征和控矿条件是明确其油页岩成矿特征与成矿规律的重要基础,为进一步指导勘探与有利区预测提供理论支撑。通过野外地质调查和地球化学实验分析等方法相结合,认为准噶尔盆地南缘2个油页岩群分别发育于中二叠统芦草沟组一、二段,以位于一段下亚段第一油页岩群的工业意义最大;油页岩以低品级为主,体积分数达77.19%,属于高灰分油页岩;滨浅湖和深湖形成的油页岩类型以深灰-棕灰色泥岩与夹白云岩薄层的页岩为主,泥灰岩次之且常与灰质粉砂岩或灰岩呈伴生关系,物缘区母岩类型是控制油页岩化学成分的重要因素之一;火山事件对油页岩区物源的控制大于其对成矿终止的控制。