多不饱和脂肪酸对谷氨酸诱导的大鼠海马神经细胞损伤的双重影响

通过测定原代培养的谷氨酸诱导的受损海马神经的细胞存活率,谷胱甘肽过氧化物酶活性,以及谷胱甘肽和一氧化氮的水平,研究多不饱和脂肪酸,如二十二碳六烯酸(docosahexaenoic acid,DHA)、花生四烯酸(arachidonic acid,AA),对大鼠海马神经细胞损伤的影响.海马神经元用神经特异性烯醇化酶进行鉴定.研究发现:(1)DHA 5～50 mg/L能有效的对抗谷氨酸诱导的海马神经细胞的损害作用.表现在细胞存活率、谷胱甘肽过氧化物酶的活性较谷氨酸处理组明显提高,NO水平降低,谷胱甘肽含量与对照组相比变化不大.(2)5 mg/LAA对损伤没有影响,而30和50 mg/LAA对损伤具有加重作用,其细胞存活率、GSH-Px活性、GSH水平较谷氨酸处理组明显降低.结果表明,多不饱和脂肪酸对谷氨酸诱导的神经细胞损伤具有双重作用.     

二十二碳六烯酸乙酯对沙土鼠缺血再灌注脑损伤及水肿作用的研究

研究二十二碳六烯酸乙酯(E-DHA)对沙土鼠缺血再灌注脑损伤及其脑水肿的影响.选用雄性断奶沙土鼠灌胃给予二十二碳六烯酸乙酯(150 mg/(kg·d))或等体积溶媒10周,阻断沙土鼠双侧颈总动脉血流10 min,造成缺血再灌注模型;测定再灌注后脑组织中丙二醛(MDA)水平,还原型谷胱甘肽(GSH)含量,超歧化氧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)和钾、钠-ATP酶(Na ,K -ATPase)活性,脑水含量,钠、钾离子浓度及海马CA1区神经细胞存活百分数.结果表明:E-DHA预处理显著降低缺血再灌注沙土鼠脑组织MDA水平,阻止GSH含量、GSH-PX和Na ,K -ATPase活性下降,而对SOD的活性未表现出明显作用;E-DHA亦调节缺血再灌注沙土鼠脑组织钠、钾离子浓度,减轻缺血再灌注所致的脑水肿和神经细胞死亡.提示E-DHA对脑缺血再灌注脑损伤有显著保护作用,机制可能其与抗氧化作用有关.     

JANSIM:基于Java的主动网络仿真模块

原有的主动网络仿真模块对于现有主动网系统的支持度较低，使得开发成本和学习成本都很高。基于Java的主动网络仿真模块JANSIM，实现了在ANTS上开发的主动协议可以无需重新在仿真环境下重新编写即可利用仿真环境的网络仿真功能对其进行仿真测试，从而大幅度的降低了主动网协议开发者的学习成本和移植成本。JANSIM包括ANTS-ESIB的适配嚣包、ANTS协议转换器和ANTS脚本转换器。ANTS-ESIB适配器可以使得基于JANSIM新开发的ANTS应用直接运行在仿真系统上，两个转换器则可以使得原先开发的ANTS协议和脚本自动转换为基于JANSIM的协议，从而在仿真环境下运行。     

对中小煤矿矿工的若干思考

中小煤矿是我国煤炭产业的重要组成部分,同时也是煤矿事故的多发领域,中小煤矿矿工就成了煤矿事故的直接受害者。煤矿的安全生产是通过矿工直接实现的,对矿工的研究构成了减少中小煤矿事故的重要手段。对吕梁中部某小煤矿矿工进行了调查,通过对收集数据的分析,初步总结了中小煤矿中矿工自身素质、工种差异、煤矿事故发生的相关关系等方面的规律,并且导入社会学的相关概念,为实现中小煤矿“以矿工为本”的生产理念,减少煤矿事故的发生提出了建议。     

基于SNMP协议的全局网络流量分析系统的设计与实现

针对传统的网络流量检测方法的不足,设计了一种基于SNMP协议的流量分析的网络流量监测系统. 该系统通过SNMP协议收集不同网络设备数据,并用这些数据掌握了一系列图表直观的体现网络设备间的流量和整个网络的负载状况.     

单片机仿真实验的探讨与研究

本文介绍了传统的单片机实验方法和利用Proteus（http：／／www．labcenter.co．uk）软件进行单片机仿真实验。包括从元器件的选择、电路的连结、源程序的输入及调试、仿真结果的输出，并比较了各自的特点。     

Development of the CAS-IBB single-particle microbeam for localized irradiation of living cells

A single-particle microbeam facility has been constructed at the Key Laboratory of Ion Beam Bioengineering (LIBB), Chinese Academy of Sciences (CAS). The system was designed to deliver a defined numbers of hydrogen ions, produced by a van de Graaff accelerator, in an energy range of 2.0-3.0 MeV, into an area smaller than that of the nucleus of an individual living cell. The beam is collimated by a borosilicate glass capillary that forms the beam-line exit. An integrated computer program recognizes the cells and locates them one by one over the microbeam exit for irradiation. We present technical details of the CAS-LIBB microbeam facility, particularly on the collimator, hardware, control program, as well as cell irradiation protocols available. Various factors contributing to the targeting and positioning precision are discussed along with accuracy measurement results.     

P-RC APMP PULPING OF THE TRIPLOID OF POPULUS TOMENTOSA

The technology parameters of P-RC APMP process of the triploid of populus tomentosa and the the comparison of P-RC APMP with one and two stage f pretreatment were investigated in this paper. The results showed that in the chemical pretreatment the s that affected the pulp qualities. The charge of NaOH,y in the first stage of chemical pretreatment,was related to pulp strength. The charge of H2O2 tant pulp.In addition, the ratio of NaOH to H2O2 and the on of chemicals in the first and second stage of impregnation also affected the pulp qualities. The and two-stage P-RC APMP pulp illustrated that the ulp had better brightness and breaking length, lower light scatting coefficient and opacity.     

WATER-BASED BINDERS USED IN PROCESS FORMAKING AUTOMOBLE FILTER PAPER

INTRODUTIONThe paper used as the filtration medium for automotbile filters has been traditionally treated with alcohol solution of phenolic resins. This has been done to improve the paper's strength properties and allow it to be pleated in an accordion-like shape and to hold the shape when the paper composite is cured.[1]With the onset of greater concern for environmental quality, the filter manufactures have requested paper suppliers to provide a free or lower formaldehyde-containing impr…     

BIOCHEMICAL PULPING OF REED PRETREATED BY WHITE ROT FUNGI

INTRODUCTIONThe origin of biological pulping is natural degradation of lignin by microorganism, such as white rot fungi. Many researches have been carried out, on the biological degradation of the lignin in raw materials, mostly on woods. Those researches were mainly focused on microorganism pretreatment as a prior proceeding of the mechanical pulping, for the rare possibility of pulping directly with the pretreatment by a microorganism. A series of reports showed that microorganism pretr…